Preliminary characterization of plga scaffold for interverterbral discs tissue engineering

Poly(lactic-co-glycolic acid) or (PLGA) has attracted considerable interest for biomedical applications due to its biodegradability and approval for clinical use. This study aimed to characterize PLGA in terms of swelling capacity, compression test and scanning electron microscopy (SEM). The PLGA sc...

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Main Authors:	Mohamad, Mohd Yusof, Md Nazir, Noorhidayah, Abdul Rahman, Rozlin, Mohamad Syukri, Norhamiza, Ahmad Radzi, Muhammad Aa'zamuddin, Zulkifly, Ahmad Hafiz, Sha'ban, Munirah
Format:	Article
Language:	English
Published:	Tissue Engineering and Regenerative Medicine Society of Malaysia 2014
Subjects:	R Medicine (General)
Online Access:	http://irep.iium.edu.my/41427/ http://irep.iium.edu.my/41427/ http://irep.iium.edu.my/41427/1/RR-181114-089.pdf

id	iium-41427
recordtype	eprints
spelling	iium-414272015-02-12T06:57:30Z http://irep.iium.edu.my/41427/ Preliminary characterization of plga scaffold for interverterbral discs tissue engineering Mohamad, Mohd Yusof Md Nazir, Noorhidayah Abdul Rahman, Rozlin Mohamad Syukri, Norhamiza Ahmad Radzi, Muhammad Aa'zamuddin Zulkifly, Ahmad Hafiz Sha'ban, Munirah R Medicine (General) Poly(lactic-co-glycolic acid) or (PLGA) has attracted considerable interest for biomedical applications due to its biodegradability and approval for clinical use. This study aimed to characterize PLGA in terms of swelling capacity, compression test and scanning electron microscopy (SEM). The PLGA scaffold was fabricated using the solvent casting, salt leaching technique. For swelling test, the scaffolds were subjected to soaking in water for 48 hours. Compression test was performed using Instron E300 Machine. Results indicated that PLGA had swelling ability more than 100% [201.82%±48.51]. Compressive strength of PLGA showed average load of 84.01N±39.33. SEM demonstrated interconnected pores in the scaffold. Further tests need be done to characterize PLGA and its combination with other materials in terms of degradation and thermal properties. Tissue Engineering and Regenerative Medicine Society of Malaysia 2014 Article PeerReviewed application/pdf en http://irep.iium.edu.my/41427/1/RR-181114-089.pdf Mohamad, Mohd Yusof and Md Nazir, Noorhidayah and Abdul Rahman, Rozlin and Mohamad Syukri, Norhamiza and Ahmad Radzi, Muhammad Aa'zamuddin and Zulkifly, Ahmad Hafiz and Sha'ban, Munirah (2014) Preliminary characterization of plga scaffold for interverterbral discs tissue engineering. Regenerative Research, 3 (2). pp. 160-162. ISSN 2232-0822 (Online) http://regres.tesma.org.my/pdf/RR-181114-089.pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	R Medicine (General)
spellingShingle	R Medicine (General) Mohamad, Mohd Yusof Md Nazir, Noorhidayah Abdul Rahman, Rozlin Mohamad Syukri, Norhamiza Ahmad Radzi, Muhammad Aa'zamuddin Zulkifly, Ahmad Hafiz Sha'ban, Munirah Preliminary characterization of plga scaffold for interverterbral discs tissue engineering
description	Poly(lactic-co-glycolic acid) or (PLGA) has attracted considerable interest for biomedical applications due to its biodegradability and approval for clinical use. This study aimed to characterize PLGA in terms of swelling capacity, compression test and scanning electron microscopy (SEM). The PLGA scaffold was fabricated using the solvent casting, salt leaching technique. For swelling test, the scaffolds were subjected to soaking in water for 48 hours. Compression test was performed using Instron E300 Machine. Results indicated that PLGA had swelling ability more than 100% [201.82%±48.51]. Compressive strength of PLGA showed average load of 84.01N±39.33. SEM demonstrated interconnected pores in the scaffold. Further tests need be done to characterize PLGA and its combination with other materials in terms of degradation and thermal properties.
format	Article
author	Mohamad, Mohd Yusof Md Nazir, Noorhidayah Abdul Rahman, Rozlin Mohamad Syukri, Norhamiza Ahmad Radzi, Muhammad Aa'zamuddin Zulkifly, Ahmad Hafiz Sha'ban, Munirah
author_facet	Mohamad, Mohd Yusof Md Nazir, Noorhidayah Abdul Rahman, Rozlin Mohamad Syukri, Norhamiza Ahmad Radzi, Muhammad Aa'zamuddin Zulkifly, Ahmad Hafiz Sha'ban, Munirah
author_sort	Mohamad, Mohd Yusof
title	Preliminary characterization of plga scaffold for interverterbral discs tissue engineering
title_short	Preliminary characterization of plga scaffold for interverterbral discs tissue engineering
title_full	Preliminary characterization of plga scaffold for interverterbral discs tissue engineering
title_fullStr	Preliminary characterization of plga scaffold for interverterbral discs tissue engineering
title_full_unstemmed	Preliminary characterization of plga scaffold for interverterbral discs tissue engineering
title_sort	preliminary characterization of plga scaffold for interverterbral discs tissue engineering
publisher	Tissue Engineering and Regenerative Medicine Society of Malaysia
publishDate	2014
url	http://irep.iium.edu.my/41427/ http://irep.iium.edu.my/41427/ http://irep.iium.edu.my/41427/1/RR-181114-089.pdf
first_indexed	2023-09-18T20:59:20Z
last_indexed	2023-09-18T20:59:20Z
_version_	1777410518111223808

Preliminary characterization of plga scaffold for interverterbral discs tissue engineering

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