$The in vivo studies of injection moulded 316l stainless steel fracture fixation plate$

The in vivo studies of injection moulded 316l stainless steel fracture fixation plate

INTRODUCTION: Metal Injection Moulding (MIM) is a revolutionary new class of medical implant fabrication in orthopaedics. This technology employs natural resources and holds great promises in producing large quantities of metallic parts for prosthetic implant at minimum outlay without compromising i...

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Main Authors:	Mohd Jan, Nurul Hafiza, Sha'ban, Munirah, Zulkifly, Ahmad Hafiz, Buyong, Zunariah, Omar, Mohd Afian
Format:	Conference or Workshop Item
Language:	English
Published:	2014
Subjects:	R Medicine (General)
Online Access:	http://irep.iium.edu.my/41796/ http://irep.iium.edu.my/41796/1/KAHS_RW2014_NURUL.pdf

id	iium-41796
recordtype	eprints
spelling	iium-417962015-02-18T04:55:15Z http://irep.iium.edu.my/41796/ The in vivo studies of injection moulded 316l stainless steel fracture fixation plate Mohd Jan, Nurul Hafiza Sha'ban, Munirah Zulkifly, Ahmad Hafiz Buyong, Zunariah Omar, Mohd Afian R Medicine (General) INTRODUCTION: Metal Injection Moulding (MIM) is a revolutionary new class of medical implant fabrication in orthopaedics. This technology employs natural resources and holds great promises in producing large quantities of metallic parts for prosthetic implant at minimum outlay without compromising its quality. MATERIALS AND METHODS: This present study was conducted to compare potential effects of MIM plate for internal fixation in fracture healing in New Zealand White rabbits with conventional machining plate (Synthes®) as control. Following research approval by IIUM Ethics Committee (IIUM/305/20/4/10), forty rabbits were used as model and randomly divided into two groups. All rabbits underwent single transverse mid-shaft tibial fracture surgery and fixation under anaesthesia. The fractures were fixated with either the MIM plate or conventional plate (Synthes®). The monitoring of fracture healing was carried out at week 3, 6, 9, 12 and 26 according to ISO10993-1&2:2006 Standards. The status of bony union was examined by means of plain radiographic assessment, macroscopic observation and, histological evaluation. RESULTS AND DISCUSSION: There were callus formations in both groups. Bony union was starting at week 6 post-operatively, whilst bone remodelling was completed at week 26 with evidenced by plain radiograph assessment followed by macroscopic evaluation. Histological assessment showed that both groups possessed mild to moderate callus bridging at week 3 and week 6, respectively. Complete remodelling of cortical bone was evidenced at week 26. There was no plate broke or bent during the study. CONCLUSION: These findings indicate that the MIM plate has equal potential to hold the fracture as conventional plate. Therefore, locally manufactured the MIM plate is potential to be used as an alternative internal fixator for fracture management in orthopaedic considering conservation value in economic appraisals of natural resources. 2014 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/41796/1/KAHS_RW2014_NURUL.pdf Mohd Jan, Nurul Hafiza and Sha'ban, Munirah and Zulkifly, Ahmad Hafiz and Buyong, Zunariah and Omar, Mohd Afian (2014) The in vivo studies of injection moulded 316l stainless steel fracture fixation plate. In: K.A.H.S. Research Week 2014, 17th-21st November 2014, Kulliyyah of Allied Health Sciences, IIUM. (Unpublished)
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	R Medicine (General)
spellingShingle	R Medicine (General) Mohd Jan, Nurul Hafiza Sha'ban, Munirah Zulkifly, Ahmad Hafiz Buyong, Zunariah Omar, Mohd Afian The in vivo studies of injection moulded 316l stainless steel fracture fixation plate
description	INTRODUCTION: Metal Injection Moulding (MIM) is a revolutionary new class of medical implant fabrication in orthopaedics. This technology employs natural resources and holds great promises in producing large quantities of metallic parts for prosthetic implant at minimum outlay without compromising its quality. MATERIALS AND METHODS: This present study was conducted to compare potential effects of MIM plate for internal fixation in fracture healing in New Zealand White rabbits with conventional machining plate (Synthes®) as control. Following research approval by IIUM Ethics Committee (IIUM/305/20/4/10), forty rabbits were used as model and randomly divided into two groups. All rabbits underwent single transverse mid-shaft tibial fracture surgery and fixation under anaesthesia. The fractures were fixated with either the MIM plate or conventional plate (Synthes®). The monitoring of fracture healing was carried out at week 3, 6, 9, 12 and 26 according to ISO10993-1&2:2006 Standards. The status of bony union was examined by means of plain radiographic assessment, macroscopic observation and, histological evaluation. RESULTS AND DISCUSSION: There were callus formations in both groups. Bony union was starting at week 6 post-operatively, whilst bone remodelling was completed at week 26 with evidenced by plain radiograph assessment followed by macroscopic evaluation. Histological assessment showed that both groups possessed mild to moderate callus bridging at week 3 and week 6, respectively. Complete remodelling of cortical bone was evidenced at week 26. There was no plate broke or bent during the study. CONCLUSION: These findings indicate that the MIM plate has equal potential to hold the fracture as conventional plate. Therefore, locally manufactured the MIM plate is potential to be used as an alternative internal fixator for fracture management in orthopaedic considering conservation value in economic appraisals of natural resources.
format	Conference or Workshop Item
author	Mohd Jan, Nurul Hafiza Sha'ban, Munirah Zulkifly, Ahmad Hafiz Buyong, Zunariah Omar, Mohd Afian
author_facet	Mohd Jan, Nurul Hafiza Sha'ban, Munirah Zulkifly, Ahmad Hafiz Buyong, Zunariah Omar, Mohd Afian
author_sort	Mohd Jan, Nurul Hafiza
title	The in vivo studies of injection moulded 316l stainless steel fracture fixation plate
title_short	The in vivo studies of injection moulded 316l stainless steel fracture fixation plate
title_full	The in vivo studies of injection moulded 316l stainless steel fracture fixation plate
title_fullStr	The in vivo studies of injection moulded 316l stainless steel fracture fixation plate
title_full_unstemmed	The in vivo studies of injection moulded 316l stainless steel fracture fixation plate
title_sort	in vivo studies of injection moulded 316l stainless steel fracture fixation plate
publishDate	2014
url	http://irep.iium.edu.my/41796/ http://irep.iium.edu.my/41796/1/KAHS_RW2014_NURUL.pdf
first_indexed	2023-09-18T20:59:44Z
last_indexed	2023-09-18T20:59:44Z
_version_	1777410543161704448

The in vivo studies of injection moulded 316l stainless steel fracture fixation plate

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