Effects of oil palm (elais guineensis) fruit extracts on glucose uptake activity of muscle, adipose and liver cells

The effect of oil palm (Elaeis guineensis) fruit aqueous extract (OPF) on glucose uptake activity of three different cell lines was investigated. The cell lines were incubated with different concentrations of OPF to evaluate the stimulatory effect of OPF towards glucose uptake activity of L6 myotube...

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Main Authors:	Sharif, Faez, Hamid, Muhajir, Ismail, Amin, Adam, Zainah
Format:	Article
Language:	English
Published:	Universiti Putra Malaysia Press 2014
Subjects:	QH301 Biology
Online Access:	http://irep.iium.edu.my/42573/ http://irep.iium.edu.my/42573/1/Contents_AJSTD_31%282%29_2014.pdf

id	iium-42573
recordtype	eprints
spelling	iium-425732016-02-02T04:42:00Z http://irep.iium.edu.my/42573/ Effects of oil palm (elais guineensis) fruit extracts on glucose uptake activity of muscle, adipose and liver cells Sharif, Faez Hamid, Muhajir Ismail, Amin Adam, Zainah QH301 Biology The effect of oil palm (Elaeis guineensis) fruit aqueous extract (OPF) on glucose uptake activity of three different cell lines was investigated. The cell lines were incubated with different concentrations of OPF to evaluate the stimulatory effect of OPF towards glucose uptake activity of L6 myotubes, 3T3F442A adipocytes and Chang liver cell line. The glucose uptake activities of all tested cells were enhanced in the presence of OPF extract (basal condition). Nevertheless in combination of OPF extract and 100 nM insulin, the glucose uptake activity was only significantly enhanced in L6 myotubes and 3T3F442A adipocytes cell lines. The extracts enhanced the glucose uptake into cells through either insulin-mimetic or insulin-sensitizing property or combination of these two properties. It can be suggested that the OPF extract exerts its antihyperglycemic action partly by mediated glucose uptake into the glucose-responsive disposal cells, muscle, adipose and liver. Universiti Putra Malaysia Press 2014 Article PeerReviewed application/pdf en http://irep.iium.edu.my/42573/1/Contents_AJSTD_31%282%29_2014.pdf Sharif, Faez and Hamid, Muhajir and Ismail, Amin and Adam, Zainah (2014) Effects of oil palm (elais guineensis) fruit extracts on glucose uptake activity of muscle, adipose and liver cells. ASEAN Journal on Science and Technology for Development, 31 (2). pp. 83-89. ISSN 0217-5460
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QH301 Biology
spellingShingle	QH301 Biology Sharif, Faez Hamid, Muhajir Ismail, Amin Adam, Zainah Effects of oil palm (elais guineensis) fruit extracts on glucose uptake activity of muscle, adipose and liver cells
description	The effect of oil palm (Elaeis guineensis) fruit aqueous extract (OPF) on glucose uptake activity of three different cell lines was investigated. The cell lines were incubated with different concentrations of OPF to evaluate the stimulatory effect of OPF towards glucose uptake activity of L6 myotubes, 3T3F442A adipocytes and Chang liver cell line. The glucose uptake activities of all tested cells were enhanced in the presence of OPF extract (basal condition). Nevertheless in combination of OPF extract and 100 nM insulin, the glucose uptake activity was only significantly enhanced in L6 myotubes and 3T3F442A adipocytes cell lines. The extracts enhanced the glucose uptake into cells through either insulin-mimetic or insulin-sensitizing property or combination of these two properties. It can be suggested that the OPF extract exerts its antihyperglycemic action partly by mediated glucose uptake into the glucose-responsive disposal cells, muscle, adipose and liver.
format	Article
author	Sharif, Faez Hamid, Muhajir Ismail, Amin Adam, Zainah
author_facet	Sharif, Faez Hamid, Muhajir Ismail, Amin Adam, Zainah
author_sort	Sharif, Faez
title	Effects of oil palm (elais guineensis) fruit extracts on glucose uptake activity of muscle, adipose and liver cells
title_short	Effects of oil palm (elais guineensis) fruit extracts on glucose uptake activity of muscle, adipose and liver cells
title_full	Effects of oil palm (elais guineensis) fruit extracts on glucose uptake activity of muscle, adipose and liver cells
title_fullStr	Effects of oil palm (elais guineensis) fruit extracts on glucose uptake activity of muscle, adipose and liver cells
title_full_unstemmed	Effects of oil palm (elais guineensis) fruit extracts on glucose uptake activity of muscle, adipose and liver cells
title_sort	effects of oil palm (elais guineensis) fruit extracts on glucose uptake activity of muscle, adipose and liver cells
publisher	Universiti Putra Malaysia Press
publishDate	2014
url	http://irep.iium.edu.my/42573/ http://irep.iium.edu.my/42573/1/Contents_AJSTD_31%282%29_2014.pdf
first_indexed	2023-09-18T21:00:39Z
last_indexed	2023-09-18T21:00:39Z
_version_	1777410600827092992

Effects of oil palm (elais guineensis) fruit extracts on glucose uptake activity of muscle, adipose and liver cells

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