Comparison of diabetic and non-diabetic patients undergoing endovascular revascularization for peripheral arterial disease

Peripheral arterial disease (PAD) is associated with poor outcomes. We assessed the clinical outcomes of diabetic versus non-diabetic patients with PAD who underwent peripheral transluminal angioplasty (PTA). The outcomes of 239 consecutive patients with symptomatic PAD who underwent PTA were anal...

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Main Authors:	Michael, S. Lee, Seung, Woon Rha, Seung, Kyu Han, Byoung, Geol Choi, Choi, Se Yeon, Ali, Jabar, Xu, Shaopeng, Ngow, Harris Abdullah, et al.
Format:	Article
Language:	English English
Published:	HMP Communications 2015
Subjects:	RC Internal medicine
Online Access:	http://irep.iium.edu.my/42712/ http://irep.iium.edu.my/42712/ http://irep.iium.edu.my/42712/1/Comparison_of_diabetic_and_non-diabetic_patients_undergoing_endovascular_revascularization_for_peripheral_arterial_disease.pdf http://irep.iium.edu.my/42712/3/42712_Comparison%20of%20diabetic%20and%20non-diabetic%20patients_SCOPUS.pdf

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spelling	iium-427122017-11-17T03:56:32Z http://irep.iium.edu.my/42712/ Comparison of diabetic and non-diabetic patients undergoing endovascular revascularization for peripheral arterial disease Michael, S. Lee Seung, Woon Rha Seung, Kyu Han Byoung, Geol Choi Choi, Se Yeon Ali, Jabar Xu, Shaopeng Ngow, Harris Abdullah et al., RC Internal medicine Peripheral arterial disease (PAD) is associated with poor outcomes. We assessed the clinical outcomes of diabetic versus non-diabetic patients with PAD who underwent peripheral transluminal angioplasty (PTA). The outcomes of 239 consecutive patients with symptomatic PAD who underwent PTA were analyzed. Restenosis and clinical outcomes were assessed at a follow-up of 2 years. Diabetic patients had a higher percentage of wound as the initial diagnosis for PTA (72.7% vs 14.2%; P<.001), chronic kidney disease (26.7% vs 6.3%; P<.01), need for dialysis (19.3% vs 3.1%; P<.01), and coronary artery disease (67.6% vs 50.7%; P=.02). Infrapopliteal PTA was more commonly performed in the diabetic group (70.4% vs 25.3%; P<.001). Diabetic patients had lower rates of angiographic follow-up at 8 months (38.6% vs 60.3%; P<.01). Diabetic patients had higher binary restenosis (54.4% vs 31.5%; P=.02) and had a trend toward a higher incidence of total occlusion (34.0% vs 19.5%; P=.08). At 2-year follow-up, the amputation rate was higher in the diabetic group (24.4% vs 1.5%; P<.001) despite PTA. Diabetic patients more frequently presented with critical limb ischemia compared with non-diabetic patients and had higher rates of restenosis and amputation at 2 years following standard PTA. Improved therapies are needed for this high-risk group of patients. HMP Communications 2015 Article PeerReviewed application/pdf en http://irep.iium.edu.my/42712/1/Comparison_of_diabetic_and_non-diabetic_patients_undergoing_endovascular_revascularization_for_peripheral_arterial_disease.pdf application/pdf en http://irep.iium.edu.my/42712/3/42712_Comparison%20of%20diabetic%20and%20non-diabetic%20patients_SCOPUS.pdf Michael, S. Lee and Seung, Woon Rha and Seung, Kyu Han and Byoung, Geol Choi and Choi, Se Yeon and Ali, Jabar and Xu, Shaopeng and Ngow, Harris Abdullah and et al., (2015) Comparison of diabetic and non-diabetic patients undergoing endovascular revascularization for peripheral arterial disease. The Journal of Invasive Cardiology, 27 (3). pp. 167-171. ISSN 1042-3931 http://www.invasivecardiology.com/articles/comparison-diabetic-and-non-diabetic-patients-undergoing-endovascular-revascularization
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	RC Internal medicine
spellingShingle	RC Internal medicine Michael, S. Lee Seung, Woon Rha Seung, Kyu Han Byoung, Geol Choi Choi, Se Yeon Ali, Jabar Xu, Shaopeng Ngow, Harris Abdullah et al., Comparison of diabetic and non-diabetic patients undergoing endovascular revascularization for peripheral arterial disease
description	Peripheral arterial disease (PAD) is associated with poor outcomes. We assessed the clinical outcomes of diabetic versus non-diabetic patients with PAD who underwent peripheral transluminal angioplasty (PTA). The outcomes of 239 consecutive patients with symptomatic PAD who underwent PTA were analyzed. Restenosis and clinical outcomes were assessed at a follow-up of 2 years. Diabetic patients had a higher percentage of wound as the initial diagnosis for PTA (72.7% vs 14.2%; P<.001), chronic kidney disease (26.7% vs 6.3%; P<.01), need for dialysis (19.3% vs 3.1%; P<.01), and coronary artery disease (67.6% vs 50.7%; P=.02). Infrapopliteal PTA was more commonly performed in the diabetic group (70.4% vs 25.3%; P<.001). Diabetic patients had lower rates of angiographic follow-up at 8 months (38.6% vs 60.3%; P<.01). Diabetic patients had higher binary restenosis (54.4% vs 31.5%; P=.02) and had a trend toward a higher incidence of total occlusion (34.0% vs 19.5%; P=.08). At 2-year follow-up, the amputation rate was higher in the diabetic group (24.4% vs 1.5%; P<.001) despite PTA. Diabetic patients more frequently presented with critical limb ischemia compared with non-diabetic patients and had higher rates of restenosis and amputation at 2 years following standard PTA. Improved therapies are needed for this high-risk group of patients.
format	Article
author	Michael, S. Lee Seung, Woon Rha Seung, Kyu Han Byoung, Geol Choi Choi, Se Yeon Ali, Jabar Xu, Shaopeng Ngow, Harris Abdullah et al.,
author_facet	Michael, S. Lee Seung, Woon Rha Seung, Kyu Han Byoung, Geol Choi Choi, Se Yeon Ali, Jabar Xu, Shaopeng Ngow, Harris Abdullah et al.,
author_sort	Michael, S. Lee
title	Comparison of diabetic and non-diabetic patients undergoing endovascular revascularization for peripheral arterial disease
title_short	Comparison of diabetic and non-diabetic patients undergoing endovascular revascularization for peripheral arterial disease
title_full	Comparison of diabetic and non-diabetic patients undergoing endovascular revascularization for peripheral arterial disease
title_fullStr	Comparison of diabetic and non-diabetic patients undergoing endovascular revascularization for peripheral arterial disease
title_full_unstemmed	Comparison of diabetic and non-diabetic patients undergoing endovascular revascularization for peripheral arterial disease
title_sort	comparison of diabetic and non-diabetic patients undergoing endovascular revascularization for peripheral arterial disease
publisher	HMP Communications
publishDate	2015
url	http://irep.iium.edu.my/42712/ http://irep.iium.edu.my/42712/ http://irep.iium.edu.my/42712/1/Comparison_of_diabetic_and_non-diabetic_patients_undergoing_endovascular_revascularization_for_peripheral_arterial_disease.pdf http://irep.iium.edu.my/42712/3/42712_Comparison%20of%20diabetic%20and%20non-diabetic%20patients_SCOPUS.pdf
first_indexed	2023-09-18T21:00:52Z
last_indexed	2023-09-18T21:00:52Z
_version_	1777410613803220992

Comparison of diabetic and non-diabetic patients undergoing endovascular revascularization for peripheral arterial disease

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