Antimicrobial activity of mangrove plant (Lumnitzera littorea)

Objective To investigate the antimicrobial activities of n-hexane, ethyl acetate and methanol extracts of the leaves of Lumnitzera littorea (L. littorea) against six human pathogenic microbes. Methods The antimicrobial activity was evaluated using disc diffusion and microdilution methods. Re...

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Main Authors:	Saad, Shahbudin, Bakhtiar, M. Taher, Darnis, Deny Susanti, Qaralleh, Haitham, Abdul Rahim, Nurul Afifah
Format:	Article
Language:	English
Published:	Elsevier 2011
Subjects:	RS Pharmacy and materia medica
Online Access:	http://irep.iium.edu.my/4339/ http://irep.iium.edu.my/4339/ http://irep.iium.edu.my/4339/2/Asian_pac_trop_med.pdf

id	iium-4339
recordtype	eprints
spelling	iium-43392011-12-12T06:39:05Z http://irep.iium.edu.my/4339/ Antimicrobial activity of mangrove plant (Lumnitzera littorea) Saad, Shahbudin Bakhtiar, M. Taher Darnis, Deny Susanti Qaralleh, Haitham Abdul Rahim, Nurul Afifah RS Pharmacy and materia medica Objective To investigate the antimicrobial activities of n-hexane, ethyl acetate and methanol extracts of the leaves of Lumnitzera littorea (L. littorea) against six human pathogenic microbes. Methods The antimicrobial activity was evaluated using disc diffusion and microdilution methods. Results The antimicrobial activities of the crude extracts were increased with increasing the concentration. It is clear that n-hexane extract was the most effective extract. Additionally, Gram positive Bacillus cereus (B. cereus) appear to be the most sensitive strain while Pseudomonas aeruginosa (P. aeruginosa) and the yeast strains (Candida albicans (C. albicans) and Cryptococcus neoformans (C. neoformans)) appear to be resistance to the tested concentrations since no inhibition zone was observed. The inhibition of microbial growth at concentration as low as 0.04 mg/mL indicated the potent antimicrobial activity of L. littorea extracts. Conclusions The obtained results are considered sufficient for further study to isolate the compounds responsible for the activity and suggesting the possibility of finding potent antibacterial agents from L. littorea extracts. Elsevier 2011-07 Article PeerReviewed application/pdf en http://irep.iium.edu.my/4339/2/Asian_pac_trop_med.pdf Saad, Shahbudin and Bakhtiar, M. Taher and Darnis, Deny Susanti and Qaralleh, Haitham and Abdul Rahim, Nurul Afifah (2011) Antimicrobial activity of mangrove plant (Lumnitzera littorea). Asian Pacific Journal of Tropical Medicine, 4 (7). pp. 523-525. ISSN 1995-7645 http://www.sciencedirect.com/science/journal/19957645
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RS Pharmacy and materia medica
spellingShingle	RS Pharmacy and materia medica Saad, Shahbudin Bakhtiar, M. Taher Darnis, Deny Susanti Qaralleh, Haitham Abdul Rahim, Nurul Afifah Antimicrobial activity of mangrove plant (Lumnitzera littorea)
description	Objective To investigate the antimicrobial activities of n-hexane, ethyl acetate and methanol extracts of the leaves of Lumnitzera littorea (L. littorea) against six human pathogenic microbes. Methods The antimicrobial activity was evaluated using disc diffusion and microdilution methods. Results The antimicrobial activities of the crude extracts were increased with increasing the concentration. It is clear that n-hexane extract was the most effective extract. Additionally, Gram positive Bacillus cereus (B. cereus) appear to be the most sensitive strain while Pseudomonas aeruginosa (P. aeruginosa) and the yeast strains (Candida albicans (C. albicans) and Cryptococcus neoformans (C. neoformans)) appear to be resistance to the tested concentrations since no inhibition zone was observed. The inhibition of microbial growth at concentration as low as 0.04 mg/mL indicated the potent antimicrobial activity of L. littorea extracts. Conclusions The obtained results are considered sufficient for further study to isolate the compounds responsible for the activity and suggesting the possibility of finding potent antibacterial agents from L. littorea extracts.
format	Article
author	Saad, Shahbudin Bakhtiar, M. Taher Darnis, Deny Susanti Qaralleh, Haitham Abdul Rahim, Nurul Afifah
author_facet	Saad, Shahbudin Bakhtiar, M. Taher Darnis, Deny Susanti Qaralleh, Haitham Abdul Rahim, Nurul Afifah
author_sort	Saad, Shahbudin
title	Antimicrobial activity of mangrove plant (Lumnitzera littorea)
title_short	Antimicrobial activity of mangrove plant (Lumnitzera littorea)
title_full	Antimicrobial activity of mangrove plant (Lumnitzera littorea)
title_fullStr	Antimicrobial activity of mangrove plant (Lumnitzera littorea)
title_full_unstemmed	Antimicrobial activity of mangrove plant (Lumnitzera littorea)
title_sort	antimicrobial activity of mangrove plant (lumnitzera littorea)
publisher	Elsevier
publishDate	2011
url	http://irep.iium.edu.my/4339/ http://irep.iium.edu.my/4339/ http://irep.iium.edu.my/4339/2/Asian_pac_trop_med.pdf
first_indexed	2023-09-18T20:12:31Z
last_indexed	2023-09-18T20:12:31Z
_version_	1777407571931430912

Antimicrobial activity of mangrove plant (Lumnitzera littorea)

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