The mode of antimicrobial action of Cinnamomum burmannii’s essential oil & cinnamaldehyde

The incidence of antibiotic resistance and its side effect have urged scientist to search for new antimicrobial substances. Cinnamons are rich in essential oils which mainly consist of cinnamaldehyde as its bioactive compounds. The present study was designed to postulate the mode of antimicrobial ac...

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Main Authors:	Darnis, Deny Susanti, Awang, Anis Fadhlina Izyani, Bakhtiar, M. Taher
Format:	Conference or Workshop Item
Language:	English
Published:	2015
Subjects:	QD Chemistry
Online Access:	http://irep.iium.edu.my/44303/ http://irep.iium.edu.my/44303/ http://irep.iium.edu.my/44303/1/44303.pdf

id	iium-44303
recordtype	eprints
spelling	iium-443032017-02-02T06:42:40Z http://irep.iium.edu.my/44303/ The mode of antimicrobial action of Cinnamomum burmannii’s essential oil & cinnamaldehyde Darnis, Deny Susanti Awang, Anis Fadhlina Izyani Bakhtiar, M. Taher QD Chemistry The incidence of antibiotic resistance and its side effect have urged scientist to search for new antimicrobial substances. Cinnamons are rich in essential oils which mainly consist of cinnamaldehyde as its bioactive compounds. The present study was designed to postulate the mode of antimicrobial actions of both essential oil and cinnamaldehyde against E. coli, S. aureus and C. albicans. The essential oil was extracted by steam distillation. Column chromatography was carried out in order to isolate cinnamaldehyde from the essential oil. Spectroscopic technique was used to characterize the isolated compound, cinnamaldehyde. There were four modes of action tested which included time-killing assay, salt tolerance assay, crystal violet assay and leakage of cellular metabolites. All of the tests were done in triplicate. The antimicrobial effect on the cell membrane was dose-dependent whereby stronger antimicrobial action was observed by cinnamaldehyde at concentration equal to 4×MIC (1.33 mg/mL) as compared to the essential oil. The potential of cinnamaldehyde as a potent antimicrobial compound of the cinnamon essential oil was discovered and proven to act on the cell membrane of microorganisms tested particularly against C. albicans. 2015-08 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/44303/1/44303.pdf Darnis, Deny Susanti and Awang, Anis Fadhlina Izyani and Bakhtiar, M. Taher (2015) The mode of antimicrobial action of Cinnamomum burmannii’s essential oil & cinnamaldehyde. In: 5th International Conference on Advancement in Science and Technology (iCAST 2015), 10th-12th August 2015, Impiana Resort Cherating, Kuantan, Pahang. (Unpublished) http://www.iium.edu.my/icast
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QD Chemistry
spellingShingle	QD Chemistry Darnis, Deny Susanti Awang, Anis Fadhlina Izyani Bakhtiar, M. Taher The mode of antimicrobial action of Cinnamomum burmannii’s essential oil & cinnamaldehyde
description	The incidence of antibiotic resistance and its side effect have urged scientist to search for new antimicrobial substances. Cinnamons are rich in essential oils which mainly consist of cinnamaldehyde as its bioactive compounds. The present study was designed to postulate the mode of antimicrobial actions of both essential oil and cinnamaldehyde against E. coli, S. aureus and C. albicans. The essential oil was extracted by steam distillation. Column chromatography was carried out in order to isolate cinnamaldehyde from the essential oil. Spectroscopic technique was used to characterize the isolated compound, cinnamaldehyde. There were four modes of action tested which included time-killing assay, salt tolerance assay, crystal violet assay and leakage of cellular metabolites. All of the tests were done in triplicate. The antimicrobial effect on the cell membrane was dose-dependent whereby stronger antimicrobial action was observed by cinnamaldehyde at concentration equal to 4×MIC (1.33 mg/mL) as compared to the essential oil. The potential of cinnamaldehyde as a potent antimicrobial compound of the cinnamon essential oil was discovered and proven to act on the cell membrane of microorganisms tested particularly against C. albicans.
format	Conference or Workshop Item
author	Darnis, Deny Susanti Awang, Anis Fadhlina Izyani Bakhtiar, M. Taher
author_facet	Darnis, Deny Susanti Awang, Anis Fadhlina Izyani Bakhtiar, M. Taher
author_sort	Darnis, Deny Susanti
title	The mode of antimicrobial action of Cinnamomum burmannii’s essential oil & cinnamaldehyde
title_short	The mode of antimicrobial action of Cinnamomum burmannii’s essential oil & cinnamaldehyde
title_full	The mode of antimicrobial action of Cinnamomum burmannii’s essential oil & cinnamaldehyde
title_fullStr	The mode of antimicrobial action of Cinnamomum burmannii’s essential oil & cinnamaldehyde
title_full_unstemmed	The mode of antimicrobial action of Cinnamomum burmannii’s essential oil & cinnamaldehyde
title_sort	mode of antimicrobial action of cinnamomum burmannii’s essential oil & cinnamaldehyde
publishDate	2015
url	http://irep.iium.edu.my/44303/ http://irep.iium.edu.my/44303/ http://irep.iium.edu.my/44303/1/44303.pdf
first_indexed	2023-09-18T21:03:00Z
last_indexed	2023-09-18T21:03:00Z
_version_	1777410748322938880

The mode of antimicrobial action of Cinnamomum burmannii’s essential oil & cinnamaldehyde

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