Micromachined adjustable hydrogel stamper for soft printing of biomolecules with adjustable-feature dimensions.

We report on the development of a hydrogel stamper with built-in reservoirs for soft-printing of biomolecules with adjustable feature dimensions. The stamper consists of potassium hydroxide (KOH)-etched silicon cavities onto which biomolecule-soaked low cross-linked density hydrogel with large pores...

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Main Authors:	Wan Salim, Wan Wardatul Amani, Ding, Zenwen, Ziaie, Babak
Format:	Article
Language:	English English English
Published:	American Chemical Society 2009
Subjects:	Q Science (General)
Online Access:	http://irep.iium.edu.my/44326/ http://irep.iium.edu.my/44326/ http://irep.iium.edu.my/44326/ http://irep.iium.edu.my/44326/1/salim2009.pdf http://irep.iium.edu.my/44326/7/44326_Micromachined%20hydrogel%20_scopus.pdf http://irep.iium.edu.my/44326/8/44326_Micromachined%20hydrogel%20_wos.pdf

id	iium-44326
recordtype	eprints
spelling	iium-443262017-10-02T07:56:57Z http://irep.iium.edu.my/44326/ Micromachined adjustable hydrogel stamper for soft printing of biomolecules with adjustable-feature dimensions. Wan Salim, Wan Wardatul Amani Ding, Zenwen Ziaie, Babak Q Science (General) We report on the development of a hydrogel stamper with built-in reservoirs for soft-printing of biomolecules with adjustable feature dimensions. The stamper consists of potassium hydroxide (KOH)-etched silicon cavities onto which biomolecule-soaked low cross-linked density hydrogel with large pores and low mechanical strength is loaded. Application of weight to the top surface allows for a controllable protrusion of hydrogel from the opposite nozzles. Such protrusion combined with a suitable spacer between the stamper and a substrate provides a means for printing features with dimensions depending on the applied weight. Utilizing the above method, we successfully stamped bovine serum albumin conjugated with fluorescein isothiocyanate (BSA-FITC) model proteins on hydrophilic silicon substrates with a feature dimension ratio of 20:1 using a single stamper. American Chemical Society 2009-06 Article PeerReviewed application/pdf en http://irep.iium.edu.my/44326/1/salim2009.pdf application/pdf en http://irep.iium.edu.my/44326/7/44326_Micromachined%20hydrogel%20_scopus.pdf application/pdf en http://irep.iium.edu.my/44326/8/44326_Micromachined%20hydrogel%20_wos.pdf Wan Salim, Wan Wardatul Amani and Ding, Zenwen and Ziaie, Babak (2009) Micromachined adjustable hydrogel stamper for soft printing of biomolecules with adjustable-feature dimensions. Analytical Chemistry, 81 (11). pp. 4551-4554. ISSN 0003-2700 E-ISSN 1520-6882 http://pubs.acs.org/journal/ancham 10.1021/ac900169k
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English English
topic	Q Science (General)
spellingShingle	Q Science (General) Wan Salim, Wan Wardatul Amani Ding, Zenwen Ziaie, Babak Micromachined adjustable hydrogel stamper for soft printing of biomolecules with adjustable-feature dimensions.
description	We report on the development of a hydrogel stamper with built-in reservoirs for soft-printing of biomolecules with adjustable feature dimensions. The stamper consists of potassium hydroxide (KOH)-etched silicon cavities onto which biomolecule-soaked low cross-linked density hydrogel with large pores and low mechanical strength is loaded. Application of weight to the top surface allows for a controllable protrusion of hydrogel from the opposite nozzles. Such protrusion combined with a suitable spacer between the stamper and a substrate provides a means for printing features with dimensions depending on the applied weight. Utilizing the above method, we successfully stamped bovine serum albumin conjugated with fluorescein isothiocyanate (BSA-FITC) model proteins on hydrophilic silicon substrates with a feature dimension ratio of 20:1 using a single stamper.
format	Article
author	Wan Salim, Wan Wardatul Amani Ding, Zenwen Ziaie, Babak
author_facet	Wan Salim, Wan Wardatul Amani Ding, Zenwen Ziaie, Babak
author_sort	Wan Salim, Wan Wardatul Amani
title	Micromachined adjustable hydrogel stamper for soft printing of biomolecules with adjustable-feature dimensions.
title_short	Micromachined adjustable hydrogel stamper for soft printing of biomolecules with adjustable-feature dimensions.
title_full	Micromachined adjustable hydrogel stamper for soft printing of biomolecules with adjustable-feature dimensions.
title_fullStr	Micromachined adjustable hydrogel stamper for soft printing of biomolecules with adjustable-feature dimensions.
title_full_unstemmed	Micromachined adjustable hydrogel stamper for soft printing of biomolecules with adjustable-feature dimensions.
title_sort	micromachined adjustable hydrogel stamper for soft printing of biomolecules with adjustable-feature dimensions.
publisher	American Chemical Society
publishDate	2009
url	http://irep.iium.edu.my/44326/ http://irep.iium.edu.my/44326/ http://irep.iium.edu.my/44326/ http://irep.iium.edu.my/44326/1/salim2009.pdf http://irep.iium.edu.my/44326/7/44326_Micromachined%20hydrogel%20_scopus.pdf http://irep.iium.edu.my/44326/8/44326_Micromachined%20hydrogel%20_wos.pdf
first_indexed	2023-09-18T21:03:02Z
last_indexed	2023-09-18T21:03:02Z
_version_	1777410750814355456

Micromachined adjustable hydrogel stamper for soft printing of biomolecules with adjustable-feature dimensions.

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