Cytotoxic study of Linum usitatissimum and Salvia officinallis extracts on MCF-7 cell line (comparative study)

Salvia officinallis and linum usitatissimum are two natural extracts that have been studied before and resulted to have many beneficial values, the research experiment we have done was to investigate weather both of the extracts possess anticancer activities on breast cancer MCF-7 cell line. The MCF...

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Main Authors: Shaban, Sama, Ichwan, Solachuddin J. A., Mustafa Al-Ahmad, Basma Ezzat, Kashmola, Muhanad Ali Hamdon, Mustafa, Nazih Shaban, Taher, Muhammad
Format: Conference or Workshop Item
Language:English
English
Published: 2015
Subjects:
Online Access:http://irep.iium.edu.my/44448/
http://irep.iium.edu.my/44448/
http://irep.iium.edu.my/44448/3/ICAST_PROGRAMME_BOOK_2015.pdf
http://irep.iium.edu.my/44448/4/MED-MEP21..pdf
id iium-44448
recordtype eprints
spelling iium-444482018-05-21T07:03:16Z http://irep.iium.edu.my/44448/ Cytotoxic study of Linum usitatissimum and Salvia officinallis extracts on MCF-7 cell line (comparative study) Shaban, Sama Ichwan, Solachuddin J. A. Mustafa Al-Ahmad, Basma Ezzat Kashmola, Muhanad Ali Hamdon Mustafa, Nazih Shaban Taher, Muhammad Q Science (General) RK Dentistry Salvia officinallis and linum usitatissimum are two natural extracts that have been studied before and resulted to have many beneficial values, the research experiment we have done was to investigate weather both of the extracts possess anticancer activities on breast cancer MCF-7 cell line. The MCF.7 cell line was maintained in Dulbecco’s Minimum Essential Medium (DMEM), supplemented with 10% fetal bovine serum (FBS) and 1% of penicillin and grown in 6 cm2 tissue culture dishes. A colorimetric MTT (3-(4,5-dimethythiazol-2-yl)-2,5-diphenyl tetrazolium bromide) assay was used to indicate the cell viability. The MTT test results have shown a slight gradual distraction of breast cancer cells by salvia officinallis oil and water extracts, for linum usitatissimum both oil and water extract have shown little to no growth constriction to MCF-7 breast cancer cells. In this experiment linum usitatissimum showed no cytotoxicity effects on MCF-7 in its both water and oil forms. As for Salvia officinallis there was a little growth constriction effects by its both water and oil extracts on MCF-7 cell line. 2015 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/44448/3/ICAST_PROGRAMME_BOOK_2015.pdf application/pdf en http://irep.iium.edu.my/44448/4/MED-MEP21..pdf Shaban, Sama and Ichwan, Solachuddin J. A. and Mustafa Al-Ahmad, Basma Ezzat and Kashmola, Muhanad Ali Hamdon and Mustafa, Nazih Shaban and Taher, Muhammad (2015) Cytotoxic study of Linum usitatissimum and Salvia officinallis extracts on MCF-7 cell line (comparative study). In: International Conference on Advancement in Science and Technology (iCAST 2015) - ‘Frontiers in Biotechnology’, 10-12 Aug 2015, Impiana Resort Cherating, Pahang, Malaysia. (Unpublished) http://www.iium.edu.my/icast/
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
English
topic Q Science (General)
RK Dentistry
spellingShingle Q Science (General)
RK Dentistry
Shaban, Sama
Ichwan, Solachuddin J. A.
Mustafa Al-Ahmad, Basma Ezzat
Kashmola, Muhanad Ali Hamdon
Mustafa, Nazih Shaban
Taher, Muhammad
Cytotoxic study of Linum usitatissimum and Salvia officinallis extracts on MCF-7 cell line (comparative study)
description Salvia officinallis and linum usitatissimum are two natural extracts that have been studied before and resulted to have many beneficial values, the research experiment we have done was to investigate weather both of the extracts possess anticancer activities on breast cancer MCF-7 cell line. The MCF.7 cell line was maintained in Dulbecco’s Minimum Essential Medium (DMEM), supplemented with 10% fetal bovine serum (FBS) and 1% of penicillin and grown in 6 cm2 tissue culture dishes. A colorimetric MTT (3-(4,5-dimethythiazol-2-yl)-2,5-diphenyl tetrazolium bromide) assay was used to indicate the cell viability. The MTT test results have shown a slight gradual distraction of breast cancer cells by salvia officinallis oil and water extracts, for linum usitatissimum both oil and water extract have shown little to no growth constriction to MCF-7 breast cancer cells. In this experiment linum usitatissimum showed no cytotoxicity effects on MCF-7 in its both water and oil forms. As for Salvia officinallis there was a little growth constriction effects by its both water and oil extracts on MCF-7 cell line.
format Conference or Workshop Item
author Shaban, Sama
Ichwan, Solachuddin J. A.
Mustafa Al-Ahmad, Basma Ezzat
Kashmola, Muhanad Ali Hamdon
Mustafa, Nazih Shaban
Taher, Muhammad
author_facet Shaban, Sama
Ichwan, Solachuddin J. A.
Mustafa Al-Ahmad, Basma Ezzat
Kashmola, Muhanad Ali Hamdon
Mustafa, Nazih Shaban
Taher, Muhammad
author_sort Shaban, Sama
title Cytotoxic study of Linum usitatissimum and Salvia officinallis extracts on MCF-7 cell line (comparative study)
title_short Cytotoxic study of Linum usitatissimum and Salvia officinallis extracts on MCF-7 cell line (comparative study)
title_full Cytotoxic study of Linum usitatissimum and Salvia officinallis extracts on MCF-7 cell line (comparative study)
title_fullStr Cytotoxic study of Linum usitatissimum and Salvia officinallis extracts on MCF-7 cell line (comparative study)
title_full_unstemmed Cytotoxic study of Linum usitatissimum and Salvia officinallis extracts on MCF-7 cell line (comparative study)
title_sort cytotoxic study of linum usitatissimum and salvia officinallis extracts on mcf-7 cell line (comparative study)
publishDate 2015
url http://irep.iium.edu.my/44448/
http://irep.iium.edu.my/44448/
http://irep.iium.edu.my/44448/3/ICAST_PROGRAMME_BOOK_2015.pdf
http://irep.iium.edu.my/44448/4/MED-MEP21..pdf
first_indexed 2023-09-18T21:03:11Z
last_indexed 2023-09-18T21:03:11Z
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