The effect of renal stones on serum adenosine aminohydrolase and AMP-aminohydrolase in Malaysia

Objective To verify possible associations between adenosine aminohydrolase (ADA) and AMP-aminohydrolase (AMPDA) to E3 SUMO-protein ligase NSE2 (NSMCE2) in patients with renal stones. And to isolate, purify and characterize ADA in patients with renal stones and healthy group. Methods A total...

Full description

Bibliographic Details
Main Authors:	Yusof, Faridah, Mehde, Atheer Awad, Ghazali, Hamid, Abd Rahman, Azlina
Format:	Article
Language:	English English
Published:	Elsevier 2015
Subjects:	R Medicine (General)
Online Access:	http://irep.iium.edu.my/44462/ http://irep.iium.edu.my/44462/ http://irep.iium.edu.my/44462/ http://irep.iium.edu.my/44462/1/P_62.pdf http://irep.iium.edu.my/44462/4/44462_The%20effect%20of%20renal%20stones%20on%20serum%20adenosine%20aminohydrolase%20and%20AMP-aminohydrolase%20in%20Malaysia_SCOPUS.pdf

id	iium-44462
recordtype	eprints
spelling	iium-444622017-11-17T07:44:03Z http://irep.iium.edu.my/44462/ The effect of renal stones on serum adenosine aminohydrolase and AMP-aminohydrolase in Malaysia Yusof, Faridah Mehde, Atheer Awad Ghazali, Hamid Abd Rahman, Azlina R Medicine (General) Objective To verify possible associations between adenosine aminohydrolase (ADA) and AMP-aminohydrolase (AMPDA) to E3 SUMO-protein ligase NSE2 (NSMCE2) in patients with renal stones. And to isolate, purify and characterize ADA in patients with renal stones and healthy group. Methods A total of 60 renal stones patients and 50 control were enrolled in a case–control study. The blood urea, creatinine, uric acid, protein, albumin, ADA and AMPDA were measured by colorimetric tests. The serum NSMCE2 was measured by ELISA. Results Serum ADA, AMPDA and specific activity of enzymes showed significant decrease (P < 0.05) in patients with renal stones compared to control group, mean levels of sera NSMCE2 and uric acid had a significant increase (P < 0.01 and P < 0.05, respectively) in patients compared to control group. Conclusions The present study suggests that ADA, AMP deaminase and NSMCE2 can be used as a indicator to monitor the DNA damage and inflammation disorders in the patients with kidney stones. Elsevier 2015-06 Article PeerReviewed application/pdf en http://irep.iium.edu.my/44462/1/P_62.pdf application/pdf en http://irep.iium.edu.my/44462/4/44462_The%20effect%20of%20renal%20stones%20on%20serum%20adenosine%20aminohydrolase%20and%20AMP-aminohydrolase%20in%20Malaysia_SCOPUS.pdf Yusof, Faridah and Mehde, Atheer Awad and Ghazali, Hamid and Abd Rahman, Azlina (2015) The effect of renal stones on serum adenosine aminohydrolase and AMP-aminohydrolase in Malaysia. Asian Pacific Journal of Tropical Biomedicine, 5 (6). pp. 478-484. ISSN 2221 1691 http://www.sciencedirect.com/science/article/pii/S2221169115000738 10.1016/j.apjtb.2015.04.003
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	R Medicine (General)
spellingShingle	R Medicine (General) Yusof, Faridah Mehde, Atheer Awad Ghazali, Hamid Abd Rahman, Azlina The effect of renal stones on serum adenosine aminohydrolase and AMP-aminohydrolase in Malaysia
description	Objective To verify possible associations between adenosine aminohydrolase (ADA) and AMP-aminohydrolase (AMPDA) to E3 SUMO-protein ligase NSE2 (NSMCE2) in patients with renal stones. And to isolate, purify and characterize ADA in patients with renal stones and healthy group. Methods A total of 60 renal stones patients and 50 control were enrolled in a case–control study. The blood urea, creatinine, uric acid, protein, albumin, ADA and AMPDA were measured by colorimetric tests. The serum NSMCE2 was measured by ELISA. Results Serum ADA, AMPDA and specific activity of enzymes showed significant decrease (P < 0.05) in patients with renal stones compared to control group, mean levels of sera NSMCE2 and uric acid had a significant increase (P < 0.01 and P < 0.05, respectively) in patients compared to control group. Conclusions The present study suggests that ADA, AMP deaminase and NSMCE2 can be used as a indicator to monitor the DNA damage and inflammation disorders in the patients with kidney stones.
format	Article
author	Yusof, Faridah Mehde, Atheer Awad Ghazali, Hamid Abd Rahman, Azlina
author_facet	Yusof, Faridah Mehde, Atheer Awad Ghazali, Hamid Abd Rahman, Azlina
author_sort	Yusof, Faridah
title	The effect of renal stones on serum adenosine aminohydrolase and AMP-aminohydrolase in Malaysia
title_short	The effect of renal stones on serum adenosine aminohydrolase and AMP-aminohydrolase in Malaysia
title_full	The effect of renal stones on serum adenosine aminohydrolase and AMP-aminohydrolase in Malaysia
title_fullStr	The effect of renal stones on serum adenosine aminohydrolase and AMP-aminohydrolase in Malaysia
title_full_unstemmed	The effect of renal stones on serum adenosine aminohydrolase and AMP-aminohydrolase in Malaysia
title_sort	effect of renal stones on serum adenosine aminohydrolase and amp-aminohydrolase in malaysia
publisher	Elsevier
publishDate	2015
url	http://irep.iium.edu.my/44462/ http://irep.iium.edu.my/44462/ http://irep.iium.edu.my/44462/ http://irep.iium.edu.my/44462/1/P_62.pdf http://irep.iium.edu.my/44462/4/44462_The%20effect%20of%20renal%20stones%20on%20serum%20adenosine%20aminohydrolase%20and%20AMP-aminohydrolase%20in%20Malaysia_SCOPUS.pdf
first_indexed	2023-09-18T21:03:13Z
last_indexed	2023-09-18T21:03:13Z
_version_	1777410761691234304

The effect of renal stones on serum adenosine aminohydrolase and AMP-aminohydrolase in Malaysia

Similar Items