The BLISS study: Beta-Lactam infusion in severe sepsis-randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis in a Malaysian ICU setting
Background: This study aims to determine if continuous infusion (CI) of beta-lactam antibiotics achieves the pharmacokinetic/pharmacodynamic (PK/PD) targets for time-dependent bacterial killing and/or are associated with improved clinical outcomes compared to intermittent bolus (IB) dosing in critic...
Main Authors: | Abdul Aziz, Mohd. Hafiz, Sulaiman, Helmi, Mat Nor, Mohd. Basri, Rai, Vineya, Wong, K., Hasan , Mohd Shahnaz, Wallis, Steven C, Lipman, Jeffrey, Staatz, Christine E., Roberts, Jason A. |
---|---|
Format: | Conference or Workshop Item |
Language: | English English |
Published: |
2015
|
Subjects: | |
Online Access: | http://irep.iium.edu.my/44991/ http://irep.iium.edu.my/44991/ http://irep.iium.edu.my/44991/1/BLISS_ICAACv4.pdf http://irep.iium.edu.my/44991/6/44991.pdf |
Similar Items
-
Beta-Lactam Infusion in Severe Sepsis (BLISS): a prospective, two-centre, open-labelled randomised controlled trial of continuous versus intermittent beta-lactam infusion in critically ill patients with severe sepsis
by: Abdul Aziz, Mohd. Hafiz, et al.
Published: (2016) -
Continuous versus intermittent beta-lactam infusion in severe sepsis: a meta-analysis of individual patient data from randomized trials
by: Roberts, Jason A., et al.
Published: (2016) -
Continuous infusion vs. bolus dosing: Implications for beta-lactam antibiotics
by: Abdul Aziz, Mohd. Hafiz, et al.
Published: (2012) -
Continuous beta-lactam infusion in critically ill patients: the clinical evidence
by: Abdul Aziz, Mohd. Hafiz, et al.
Published: (2012) -
Identifying “at-risk” patients for sub-optimal beta-lactam exposure in critically ill patients with severe infections
by: Abdul Aziz, Mohd. Hafiz, et al.
Published: (2017)