Synthesis, Characterization and Antioxidant Activity of 2-Halobenzoyl Thiourea Bearing α- and β-alanine

Six new 2-halobenzoylthiourea compounds bearing α- and β-alanine have been successfully synthesized and characterized using CHNS microelemental analysis and spectroscopic methods including FTIR, UV-Vis and NMR. Microelemental analysis data of the compounds were in agreement with the theoretical valu...

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Main Authors:	Ngah, Nurziana, Mohamed, Nor Azanita, Darnis, Deny Susanti
Format:	Article
Language:	English English English
Published:	Chiang Mai University 2016
Subjects:	QD Chemistry
Online Access:	http://irep.iium.edu.my/46121/ http://irep.iium.edu.my/46121/ http://irep.iium.edu.my/46121/4/16-03-22-d490d.pdf http://irep.iium.edu.my/46121/7/46121_Synthesis%2C%20Characterization%20and%20Antioxidant%20Activity%20of%202-Halobenzoyl_Scopus.pdf http://irep.iium.edu.my/46121/13/46121_Synthesis%2C%20characterization%20and%20antioxidant%20activity_wos.pdf

id	iium-46121
recordtype	eprints
spelling	iium-461212017-10-12T05:22:53Z http://irep.iium.edu.my/46121/ Synthesis, Characterization and Antioxidant Activity of 2-Halobenzoyl Thiourea Bearing α- and β-alanine Ngah, Nurziana Mohamed, Nor Azanita Darnis, Deny Susanti QD Chemistry Six new 2-halobenzoylthiourea compounds bearing α- and β-alanine have been successfully synthesized and characterized using CHNS microelemental analysis and spectroscopic methods including FTIR, UV-Vis and NMR. Microelemental analysis data of the compounds were in agreement with the theoretical values. The FTIR spectra showed the presence of important bands of the compounds while the 1 H-NMR and 13C-NMR exhibited the expected chemical shifts. The compounds exerted weak antioxidant activity in DPPH scavenging test and moderate to good activity in β-carotene bleaching test. The inclusion of halogen atoms has facilitated the released of hydrogen atoms and introduction of α- and β-alanine have increased the β-carotene bleaching and DPPH scavenging activities of the compounds. Chiang Mai University 2016 Article PeerReviewed application/pdf en http://irep.iium.edu.my/46121/4/16-03-22-d490d.pdf application/pdf en http://irep.iium.edu.my/46121/7/46121_Synthesis%2C%20Characterization%20and%20Antioxidant%20Activity%20of%202-Halobenzoyl_Scopus.pdf application/pdf en http://irep.iium.edu.my/46121/13/46121_Synthesis%2C%20characterization%20and%20antioxidant%20activity_wos.pdf Ngah, Nurziana and Mohamed, Nor Azanita and Darnis, Deny Susanti (2016) Synthesis, Characterization and Antioxidant Activity of 2-Halobenzoyl Thiourea Bearing α- and β-alanine. Chiang Mai Journal of Science, 43 (3). pp. 577-583. ISSN 0125-2526 http://it.science.cmu.ac.th/ejournal/journalDetail.php?journal_id=6816
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English English
topic	QD Chemistry
spellingShingle	QD Chemistry Ngah, Nurziana Mohamed, Nor Azanita Darnis, Deny Susanti Synthesis, Characterization and Antioxidant Activity of 2-Halobenzoyl Thiourea Bearing α- and β-alanine
description	Six new 2-halobenzoylthiourea compounds bearing α- and β-alanine have been successfully synthesized and characterized using CHNS microelemental analysis and spectroscopic methods including FTIR, UV-Vis and NMR. Microelemental analysis data of the compounds were in agreement with the theoretical values. The FTIR spectra showed the presence of important bands of the compounds while the 1 H-NMR and 13C-NMR exhibited the expected chemical shifts. The compounds exerted weak antioxidant activity in DPPH scavenging test and moderate to good activity in β-carotene bleaching test. The inclusion of halogen atoms has facilitated the released of hydrogen atoms and introduction of α- and β-alanine have increased the β-carotene bleaching and DPPH scavenging activities of the compounds.
format	Article
author	Ngah, Nurziana Mohamed, Nor Azanita Darnis, Deny Susanti
author_facet	Ngah, Nurziana Mohamed, Nor Azanita Darnis, Deny Susanti
author_sort	Ngah, Nurziana
title	Synthesis, Characterization and Antioxidant Activity of 2-Halobenzoyl Thiourea Bearing α- and β-alanine
title_short	Synthesis, Characterization and Antioxidant Activity of 2-Halobenzoyl Thiourea Bearing α- and β-alanine
title_full	Synthesis, Characterization and Antioxidant Activity of 2-Halobenzoyl Thiourea Bearing α- and β-alanine
title_fullStr	Synthesis, Characterization and Antioxidant Activity of 2-Halobenzoyl Thiourea Bearing α- and β-alanine
title_full_unstemmed	Synthesis, Characterization and Antioxidant Activity of 2-Halobenzoyl Thiourea Bearing α- and β-alanine
title_sort	synthesis, characterization and antioxidant activity of 2-halobenzoyl thiourea bearing α- and β-alanine
publisher	Chiang Mai University
publishDate	2016
url	http://irep.iium.edu.my/46121/ http://irep.iium.edu.my/46121/ http://irep.iium.edu.my/46121/4/16-03-22-d490d.pdf http://irep.iium.edu.my/46121/7/46121_Synthesis%2C%20Characterization%20and%20Antioxidant%20Activity%20of%202-Halobenzoyl_Scopus.pdf http://irep.iium.edu.my/46121/13/46121_Synthesis%2C%20characterization%20and%20antioxidant%20activity_wos.pdf
first_indexed	2023-09-18T21:05:40Z
last_indexed	2023-09-18T21:05:40Z
_version_	1777410915783671808

Synthesis, Characterization and Antioxidant Activity of 2-Halobenzoyl Thiourea Bearing α- and β-alanine

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