Distribution pattern of hepatitis C virus in eastern peninsular Malaysia for the past decade

Introduction: Analysis of the Hepatitis C Virus (HCV) genotype spread in a particular area has a crucial impact on public health. Genotyping is essential before initiating treatment. Methods: This is a hospital-based cohort of 133 chronic hepatitis C patients, collected prospectively among subje...

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Main Authors:	Hasmoni, Mohamed Hadzri, Jaafar, Khairul Azhar, Che Aun, Azlida, Tee, Hoi Poh
Format:	Article
Language:	English
Published:	Wiley Publishing Asia Pty Ltd 2015
Subjects:	RC Internal medicine
Online Access:	http://irep.iium.edu.my/47476/ http://irep.iium.edu.my/47476/ http://irep.iium.edu.my/47476/2/2015-Journal_of_Gastroenterology_and_Hepatology.pdf

id	iium-47476
recordtype	eprints
spelling	iium-474762016-12-06T08:54:54Z http://irep.iium.edu.my/47476/ Distribution pattern of hepatitis C virus in eastern peninsular Malaysia for the past decade Hasmoni, Mohamed Hadzri Jaafar, Khairul Azhar Che Aun, Azlida Tee, Hoi Poh RC Internal medicine Introduction: Analysis of the Hepatitis C Virus (HCV) genotype spread in a particular area has a crucial impact on public health. Genotyping is essential before initiating treatment. Methods: This is a hospital-based cohort of 133 chronic hepatitis C patients, collected prospectively among subjects attending Hospital Tengku Ampuan Afzan, Kuantan, within an area of eastern Peninsular Malaysia. We assessed the rate and distribution of HCV genotypes during two consecutive periods, from 2005 to 2006 and from 2013 to 2014, according to age, gender, race and risk factors. Results: Genotypes 3 and 1 were predominant followed by genotype 4 and 6. Statistical evaluation of the demographic of HCV patients stratified by genotypes did not revealed any significant difference between the two periods. There was no association between the risk factors analyzed and the acquisition of different HCV genotypes. However, there was significant difference for the treatment received in the second cohort (p<0.005). Wiley Publishing Asia Pty Ltd 2015-12 Article PeerReviewed application/pdf en cc_public_domain http://irep.iium.edu.my/47476/2/2015-Journal_of_Gastroenterology_and_Hepatology.pdf Hasmoni, Mohamed Hadzri and Jaafar, Khairul Azhar and Che Aun, Azlida and Tee, Hoi Poh (2015) Distribution pattern of hepatitis C virus in eastern peninsular Malaysia for the past decade. Journal of Gastroenterology and Hepatology, 30 (S4). p. 375. ISSN 0815-9319 http://wileyonlinelibrary.com/journal/jgh
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RC Internal medicine
spellingShingle	RC Internal medicine Hasmoni, Mohamed Hadzri Jaafar, Khairul Azhar Che Aun, Azlida Tee, Hoi Poh Distribution pattern of hepatitis C virus in eastern peninsular Malaysia for the past decade
description	Introduction: Analysis of the Hepatitis C Virus (HCV) genotype spread in a particular area has a crucial impact on public health. Genotyping is essential before initiating treatment. Methods: This is a hospital-based cohort of 133 chronic hepatitis C patients, collected prospectively among subjects attending Hospital Tengku Ampuan Afzan, Kuantan, within an area of eastern Peninsular Malaysia. We assessed the rate and distribution of HCV genotypes during two consecutive periods, from 2005 to 2006 and from 2013 to 2014, according to age, gender, race and risk factors. Results: Genotypes 3 and 1 were predominant followed by genotype 4 and 6. Statistical evaluation of the demographic of HCV patients stratified by genotypes did not revealed any significant difference between the two periods. There was no association between the risk factors analyzed and the acquisition of different HCV genotypes. However, there was significant difference for the treatment received in the second cohort (p<0.005).
format	Article
author	Hasmoni, Mohamed Hadzri Jaafar, Khairul Azhar Che Aun, Azlida Tee, Hoi Poh
author_facet	Hasmoni, Mohamed Hadzri Jaafar, Khairul Azhar Che Aun, Azlida Tee, Hoi Poh
author_sort	Hasmoni, Mohamed Hadzri
title	Distribution pattern of hepatitis C virus in eastern peninsular Malaysia for the past decade
title_short	Distribution pattern of hepatitis C virus in eastern peninsular Malaysia for the past decade
title_full	Distribution pattern of hepatitis C virus in eastern peninsular Malaysia for the past decade
title_fullStr	Distribution pattern of hepatitis C virus in eastern peninsular Malaysia for the past decade
title_full_unstemmed	Distribution pattern of hepatitis C virus in eastern peninsular Malaysia for the past decade
title_sort	distribution pattern of hepatitis c virus in eastern peninsular malaysia for the past decade
publisher	Wiley Publishing Asia Pty Ltd
publishDate	2015
url	http://irep.iium.edu.my/47476/ http://irep.iium.edu.my/47476/ http://irep.iium.edu.my/47476/2/2015-Journal_of_Gastroenterology_and_Hepatology.pdf
first_indexed	2023-09-18T21:07:33Z
last_indexed	2023-09-18T21:07:33Z
_version_	1777411034979500032

Distribution pattern of hepatitis C virus in eastern peninsular Malaysia for the past decade

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