Nanoparticle preparation of Mefenamic acid by electrospray drying

Nanoparticles preparation of Mefenamic acid (MA) by using an electrospray drying method was conducted in this study. Electrospray drying is a process that uses electrostatic force to disperse a conductive liquid stream into fine charged droplets through the coulomb fission of charges in the liquid...

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Main Authors:	Zolkepali, Nurul Karimah, Abu Bakar, Noor Fitrah, Naim, Mohd Nazli, Anuar, Nornizar, Abu Bakar, Mohd Rushdi
Format:	Conference or Workshop Item
Language:	English English
Published:	American Institute of Physics 2014
Subjects:	TP155 Chemical engineering
Online Access:	http://irep.iium.edu.my/48672/ http://irep.iium.edu.my/48672/ http://irep.iium.edu.my/48672/ http://irep.iium.edu.my/48672/1/48672_Nanoparticle%20preparation_complete.pdf http://irep.iium.edu.my/48672/2/48672_Nanoparticle%20preparation_scopus.pdf

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recordtype	eprints
spelling	iium-486722017-09-21T10:42:45Z http://irep.iium.edu.my/48672/ Nanoparticle preparation of Mefenamic acid by electrospray drying Zolkepali, Nurul Karimah Abu Bakar, Noor Fitrah Naim, Mohd Nazli Anuar, Nornizar Abu Bakar, Mohd Rushdi TP155 Chemical engineering Nanoparticles preparation of Mefenamic acid (MA) by using an electrospray drying method was conducted in this study. Electrospray drying is a process that uses electrostatic force to disperse a conductive liquid stream into fine charged droplets through the coulomb fission of charges in the liquid and finally dry into fine particles. Electrospray drying modes operation usually in Taylor cone jet, and it was formed by controlling applied voltage and liquid flow rate. A conductive liquid (2.77- 8.55μScm-1) which is MA solution was prepared by using acetone with concentration 0.041 and 0.055 M before pumping at a flow rate of 3-6ml/h. By applying the applied voltage at 1.3-1.5 kV, Taylor cone jet mode was formed prior to the electrospray. During electrospray drying process, solvent evaporation from the droplet was occurring that leads to coulomb disruption and may generate to nanoparticles. The dried nanoparticles were collected on a grounded substrate that was placed at varying distance from the electrospray. MA particle with size range of 100-400 nm were produced by electrospray drying process. Characterization of particles by using X-ray diffractometry (XRD) and differential scanning calorimetry (DSC) show that particles formed into polymorph I. American Institute of Physics 2014 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/48672/1/48672_Nanoparticle%20preparation_complete.pdf application/pdf en http://irep.iium.edu.my/48672/2/48672_Nanoparticle%20preparation_scopus.pdf Zolkepali, Nurul Karimah and Abu Bakar, Noor Fitrah and Naim, Mohd Nazli and Anuar, Nornizar and Abu Bakar, Mohd Rushdi (2014) Nanoparticle preparation of Mefenamic acid by electrospray drying. In: 5th Nanoscience and Nanotechnology Symposium (NNS2013), 23rd-25th October 2013, Surabaya, indonesia. http://scitation.aip.org/content/aip/proceeding/aipcp/1586?ver=pdfcov 10.1063/1.4866742
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	TP155 Chemical engineering
spellingShingle	TP155 Chemical engineering Zolkepali, Nurul Karimah Abu Bakar, Noor Fitrah Naim, Mohd Nazli Anuar, Nornizar Abu Bakar, Mohd Rushdi Nanoparticle preparation of Mefenamic acid by electrospray drying
description	Nanoparticles preparation of Mefenamic acid (MA) by using an electrospray drying method was conducted in this study. Electrospray drying is a process that uses electrostatic force to disperse a conductive liquid stream into fine charged droplets through the coulomb fission of charges in the liquid and finally dry into fine particles. Electrospray drying modes operation usually in Taylor cone jet, and it was formed by controlling applied voltage and liquid flow rate. A conductive liquid (2.77- 8.55μScm-1) which is MA solution was prepared by using acetone with concentration 0.041 and 0.055 M before pumping at a flow rate of 3-6ml/h. By applying the applied voltage at 1.3-1.5 kV, Taylor cone jet mode was formed prior to the electrospray. During electrospray drying process, solvent evaporation from the droplet was occurring that leads to coulomb disruption and may generate to nanoparticles. The dried nanoparticles were collected on a grounded substrate that was placed at varying distance from the electrospray. MA particle with size range of 100-400 nm were produced by electrospray drying process. Characterization of particles by using X-ray diffractometry (XRD) and differential scanning calorimetry (DSC) show that particles formed into polymorph I.
format	Conference or Workshop Item
author	Zolkepali, Nurul Karimah Abu Bakar, Noor Fitrah Naim, Mohd Nazli Anuar, Nornizar Abu Bakar, Mohd Rushdi
author_facet	Zolkepali, Nurul Karimah Abu Bakar, Noor Fitrah Naim, Mohd Nazli Anuar, Nornizar Abu Bakar, Mohd Rushdi
author_sort	Zolkepali, Nurul Karimah
title	Nanoparticle preparation of Mefenamic acid by electrospray drying
title_short	Nanoparticle preparation of Mefenamic acid by electrospray drying
title_full	Nanoparticle preparation of Mefenamic acid by electrospray drying
title_fullStr	Nanoparticle preparation of Mefenamic acid by electrospray drying
title_full_unstemmed	Nanoparticle preparation of Mefenamic acid by electrospray drying
title_sort	nanoparticle preparation of mefenamic acid by electrospray drying
publisher	American Institute of Physics
publishDate	2014
url	http://irep.iium.edu.my/48672/ http://irep.iium.edu.my/48672/ http://irep.iium.edu.my/48672/ http://irep.iium.edu.my/48672/1/48672_Nanoparticle%20preparation_complete.pdf http://irep.iium.edu.my/48672/2/48672_Nanoparticle%20preparation_scopus.pdf
first_indexed	2023-09-18T21:08:59Z
last_indexed	2023-09-18T21:08:59Z
_version_	1777411124919009280

Nanoparticle preparation of Mefenamic acid by electrospray drying

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