Non Hodgkin lymphoma presenting with adrenal insufficiency and bilateral huge adrenal masses
Adrenal involvement secondary to lymphoma is not commonly seen. We report a case of a 62-year old lady, with underlying hypertension on treatment, but otherwise healthy, presented with adrenal insufficiency with large bilateral adrenal masses, complicated with exudative left pleural effusion. Sh...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Malaysian Endocrine and Metabolic Society
2014
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/49068/ http://irep.iium.edu.my/49068/ http://irep.iium.edu.my/49068/1/PP-042.pdf |
| Summary: | Adrenal involvement secondary to lymphoma is not commonly seen.
We report a case of a 62-year old lady, with underlying hypertension on
treatment, but otherwise healthy, presented with adrenal insufficiency
with large bilateral adrenal masses, complicated with exudative left
pleural effusion. She responded to intravenous hydrocortisone of 50mg
tds. Computed tomography (CT) showed large heterogenous bilateral
suprarenal masses (Figure 1, Figure 2). There were areas of necrosis with
no calcification within the mass. Multiple lymphadenopathy in the abdominal
region and mediastinum were noted. Lactate dehydrogenase level was
elevated. Fungal and tuberculous cultures were negative. Trucut biopsy
of the lesion showed Diffuse Large B cell Lymphoma. She was started
on chemotherapy (Rituximab-CHOP). Secondary involvement of bilateral
adrenal glands due to widespread lymphoma is not common, with Diffuse
Large B cell Lymphoma being the most frequently seen. This is to highlight
lymphoma as a possible cause of patient presenting with large bilateral
adrenal masses and adrenal insufficiency. |
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