Extraction and isolation of xanthine oxidase inhibitors from carica papaya leave extract using chromatographic techniques

Xanthine oxidase (XO) is a key enzyme that catalyses the oxidation of oxypurines (hypoxanthine and xanthine) to uric acid in the purine metabolic pathway.The increase level of uric acid in the blood serum is called hyperuricemia. Its major complications are gout, urolithiasis and reactive oxygen pro...

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Main Authors: Jamal, Parveen, Azmi, Saiful Mohammad Nizam, Amid, Azura
Format: Book Chapter
Language:English
Published: IIUM Press 2016
Subjects:
Online Access:http://irep.iium.edu.my/49678/
http://irep.iium.edu.my/49678/
http://irep.iium.edu.my/49678/1/49678_Extraction_and_isolation_of_xanthine_oxidase_inhibitors_from_carica_papaya_leave_extract_using_chromatographic_techniques.pdf
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spelling iium-496782017-02-21T02:09:11Z http://irep.iium.edu.my/49678/ Extraction and isolation of xanthine oxidase inhibitors from carica papaya leave extract using chromatographic techniques Jamal, Parveen Azmi, Saiful Mohammad Nizam Amid, Azura T Technology (General) TP248.13 Biotechnology Xanthine oxidase (XO) is a key enzyme that catalyses the oxidation of oxypurines (hypoxanthine and xanthine) to uric acid in the purine metabolic pathway.The increase level of uric acid in the blood serum is called hyperuricemia. Its major complications are gout, urolithiasis and reactive oxygen production. In addition, some diseases are frequently seen with elevated uric acid concentration such as cardiovascular disease and renal insufficiency (Nakagawa et al., 2006), although no direct role has yet been confirmed. Xanthine oxidase inhibitor (XOI) could block the biosynthesis of uric acid from purine in the body, which should be one of the therapeutic approaches for treating hyperuricemia. IIUM Press Jamal, Parveen Noorbatcha, Ibrahim Ali Azmi, Azlin Suhaida 2016 Book Chapter PeerReviewed application/pdf en http://irep.iium.edu.my/49678/1/49678_Extraction_and_isolation_of_xanthine_oxidase_inhibitors_from_carica_papaya_leave_extract_using_chromatographic_techniques.pdf Jamal, Parveen and Azmi, Saiful Mohammad Nizam and Amid, Azura (2016) Extraction and isolation of xanthine oxidase inhibitors from carica papaya leave extract using chromatographic techniques. In: Experimental methods in modern biotechnology. IIUM Press Series of Textbook from the Islamic Perspectives, 2 . IIUM Press, Kuala Lumpur, pp. 25-35. ISBN 978-967-418-384-4 http://iiumpress.iium.edu.my/bookshop/experimental-methods-in-modern-biotechnology
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic T Technology (General)
TP248.13 Biotechnology
spellingShingle T Technology (General)
TP248.13 Biotechnology
Jamal, Parveen
Azmi, Saiful Mohammad Nizam
Amid, Azura
Extraction and isolation of xanthine oxidase inhibitors from carica papaya leave extract using chromatographic techniques
description Xanthine oxidase (XO) is a key enzyme that catalyses the oxidation of oxypurines (hypoxanthine and xanthine) to uric acid in the purine metabolic pathway.The increase level of uric acid in the blood serum is called hyperuricemia. Its major complications are gout, urolithiasis and reactive oxygen production. In addition, some diseases are frequently seen with elevated uric acid concentration such as cardiovascular disease and renal insufficiency (Nakagawa et al., 2006), although no direct role has yet been confirmed. Xanthine oxidase inhibitor (XOI) could block the biosynthesis of uric acid from purine in the body, which should be one of the therapeutic approaches for treating hyperuricemia.
author2 Jamal, Parveen
author_facet Jamal, Parveen
Jamal, Parveen
Azmi, Saiful Mohammad Nizam
Amid, Azura
format Book Chapter
author Jamal, Parveen
Azmi, Saiful Mohammad Nizam
Amid, Azura
author_sort Jamal, Parveen
title Extraction and isolation of xanthine oxidase inhibitors from carica papaya leave extract using chromatographic techniques
title_short Extraction and isolation of xanthine oxidase inhibitors from carica papaya leave extract using chromatographic techniques
title_full Extraction and isolation of xanthine oxidase inhibitors from carica papaya leave extract using chromatographic techniques
title_fullStr Extraction and isolation of xanthine oxidase inhibitors from carica papaya leave extract using chromatographic techniques
title_full_unstemmed Extraction and isolation of xanthine oxidase inhibitors from carica papaya leave extract using chromatographic techniques
title_sort extraction and isolation of xanthine oxidase inhibitors from carica papaya leave extract using chromatographic techniques
publisher IIUM Press
publishDate 2016
url http://irep.iium.edu.my/49678/
http://irep.iium.edu.my/49678/
http://irep.iium.edu.my/49678/1/49678_Extraction_and_isolation_of_xanthine_oxidase_inhibitors_from_carica_papaya_leave_extract_using_chromatographic_techniques.pdf
first_indexed 2023-09-18T21:10:13Z
last_indexed 2023-09-18T21:10:13Z
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