Comparison of dry eye parameters between diabetics and non-diabetics in district of Kuantan, Pahang

Introduction: Diabetes may affect the human body’s systems and organs, including the eye. Diabetic retinopathy is the 5th leading cause of blindness globally. Diabetic subjects demonstrated dry eye symptoms that were also supported by the low values of the clinical tests. Purpose: This study aime...

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Main Authors: Aljarousha, Mohammed, Badarudin, Noor Ezailina, Che Azemin, Mohd Zulfaezal
Format: Article
Language:English
English
English
Published: Universiti Sains Malaysia 2016
Subjects:
Online Access:http://irep.iium.edu.my/50603/
http://irep.iium.edu.my/50603/
http://irep.iium.edu.my/50603/1/50603_Comparison%20of%20dry%20eye.pdf
http://irep.iium.edu.my/50603/2/50603_Comparison%20of%20dry%20eye_SCOPUS.pdf
http://irep.iium.edu.my/50603/13/50603_Comparison%20of%20Dry%20Eye%20Parameters%20between%20Diabetics%20_wos.pdf
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spelling iium-506032020-02-06T02:23:59Z http://irep.iium.edu.my/50603/ Comparison of dry eye parameters between diabetics and non-diabetics in district of Kuantan, Pahang Aljarousha, Mohammed Badarudin, Noor Ezailina Che Azemin, Mohd Zulfaezal RE Ophthalmology Introduction: Diabetes may affect the human body’s systems and organs, including the eye. Diabetic retinopathy is the 5th leading cause of blindness globally. Diabetic subjects demonstrated dry eye symptoms that were also supported by the low values of the clinical tests. Purpose: This study aimed to compare the dry eye symptoms and signs between diabetics and non-diabetics and tear functions between diabetic subjects with and without dry eye. Methods: This retrospective study was based on the observation of 643 medical files. Using a convenience sampling method, 88 subjects were found to report diabetes mellitus. The information extracted from the files included: date of first examination, age at first visit, gender, past ocular history, systemic disease, symptoms of dry eye disease and details of clinical diagnostic signs. Noncontact lens wearers were excluded. A group of 88, age and gender matched, control subjects were included for this comparison study. Results: The percentage of dry eye symptoms was higher in diabetic subjects (15.9%) compared with non-diabetic subjects (13.6%; p<0.001). The percentage of dry eye symptoms was also higher in diabetics with dry eye (63%) than in diabetics without dry eye (36.9%; p<0.001). Tear break up time was significantly different between diabetics and non-diabetics (p<0.001) and between diabetics with and without dry eye (p=0.046). The corneal staining was significantly different between diabetic subjects with and without dry eye (p=0.028). Conclusion: Dry eye symptoms were significantly associated with diabetics. Tear break up time was significantly shorter in diabetics with dry eye compared to diabetics without dry eye. Universiti Sains Malaysia 2016 Article PeerReviewed application/pdf en http://irep.iium.edu.my/50603/1/50603_Comparison%20of%20dry%20eye.pdf application/pdf en http://irep.iium.edu.my/50603/2/50603_Comparison%20of%20dry%20eye_SCOPUS.pdf application/pdf en http://irep.iium.edu.my/50603/13/50603_Comparison%20of%20Dry%20Eye%20Parameters%20between%20Diabetics%20_wos.pdf Aljarousha, Mohammed and Badarudin, Noor Ezailina and Che Azemin, Mohd Zulfaezal (2016) Comparison of dry eye parameters between diabetics and non-diabetics in district of Kuantan, Pahang. Malaysian Journal of Medical Sciences, 23 (3). pp. 72-77. ISSN 1394-195X E-ISSN 2180-4303 http://www.mjms.usm.my/default.asp?tag=12
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
English
English
topic RE Ophthalmology
spellingShingle RE Ophthalmology
Aljarousha, Mohammed
Badarudin, Noor Ezailina
Che Azemin, Mohd Zulfaezal
Comparison of dry eye parameters between diabetics and non-diabetics in district of Kuantan, Pahang
description Introduction: Diabetes may affect the human body’s systems and organs, including the eye. Diabetic retinopathy is the 5th leading cause of blindness globally. Diabetic subjects demonstrated dry eye symptoms that were also supported by the low values of the clinical tests. Purpose: This study aimed to compare the dry eye symptoms and signs between diabetics and non-diabetics and tear functions between diabetic subjects with and without dry eye. Methods: This retrospective study was based on the observation of 643 medical files. Using a convenience sampling method, 88 subjects were found to report diabetes mellitus. The information extracted from the files included: date of first examination, age at first visit, gender, past ocular history, systemic disease, symptoms of dry eye disease and details of clinical diagnostic signs. Noncontact lens wearers were excluded. A group of 88, age and gender matched, control subjects were included for this comparison study. Results: The percentage of dry eye symptoms was higher in diabetic subjects (15.9%) compared with non-diabetic subjects (13.6%; p<0.001). The percentage of dry eye symptoms was also higher in diabetics with dry eye (63%) than in diabetics without dry eye (36.9%; p<0.001). Tear break up time was significantly different between diabetics and non-diabetics (p<0.001) and between diabetics with and without dry eye (p=0.046). The corneal staining was significantly different between diabetic subjects with and without dry eye (p=0.028). Conclusion: Dry eye symptoms were significantly associated with diabetics. Tear break up time was significantly shorter in diabetics with dry eye compared to diabetics without dry eye.
format Article
author Aljarousha, Mohammed
Badarudin, Noor Ezailina
Che Azemin, Mohd Zulfaezal
author_facet Aljarousha, Mohammed
Badarudin, Noor Ezailina
Che Azemin, Mohd Zulfaezal
author_sort Aljarousha, Mohammed
title Comparison of dry eye parameters between diabetics and non-diabetics in district of Kuantan, Pahang
title_short Comparison of dry eye parameters between diabetics and non-diabetics in district of Kuantan, Pahang
title_full Comparison of dry eye parameters between diabetics and non-diabetics in district of Kuantan, Pahang
title_fullStr Comparison of dry eye parameters between diabetics and non-diabetics in district of Kuantan, Pahang
title_full_unstemmed Comparison of dry eye parameters between diabetics and non-diabetics in district of Kuantan, Pahang
title_sort comparison of dry eye parameters between diabetics and non-diabetics in district of kuantan, pahang
publisher Universiti Sains Malaysia
publishDate 2016
url http://irep.iium.edu.my/50603/
http://irep.iium.edu.my/50603/
http://irep.iium.edu.my/50603/1/50603_Comparison%20of%20dry%20eye.pdf
http://irep.iium.edu.my/50603/2/50603_Comparison%20of%20dry%20eye_SCOPUS.pdf
http://irep.iium.edu.my/50603/13/50603_Comparison%20of%20Dry%20Eye%20Parameters%20between%20Diabetics%20_wos.pdf
first_indexed 2023-09-18T21:11:32Z
last_indexed 2023-09-18T21:11:32Z
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