Distribution pattern of hepatitis c virus in eastern peninsular malaysia for the past decade

Introduction: Analysis of the Hepatitis C Virus’ (HCV) genotypic spread in a particular area has a crucial impact on public health. Genotyping is essential before initiating treatment. Methodology: This is a hospital-based cohort of 133 chronic hepatitis C patients, collected prospectively among su...

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Main Authors:	H.M, Hadzr, Tee, Hoi Poh, Che Aun, Azlida
Format:	Article
Language:	English
Published:	The Faculty of Medicine, International Islamic University Malaysia 2015
Subjects:	RC Internal medicine
Online Access:	http://irep.iium.edu.my/50719/ http://irep.iium.edu.my/50719/ http://irep.iium.edu.my/50719/1/50719_-_Distribution_pattern_of_hepatitis_c_virus_in_eastern_peninsular_malaysia_for_the_past_decade.pdf

id	iium-50719
recordtype	eprints
spelling	iium-507192016-07-19T02:29:21Z http://irep.iium.edu.my/50719/ Distribution pattern of hepatitis c virus in eastern peninsular malaysia for the past decade H.M, Hadzr Tee, Hoi Poh Che Aun, Azlida RC Internal medicine Introduction: Analysis of the Hepatitis C Virus’ (HCV) genotypic spread in a particular area has a crucial impact on public health. Genotyping is essential before initiating treatment. Methodology: This is a hospital-based cohort of 133 chronic hepatitis C patients, collected prospectively among subjects attending Hospital Tengku Ampuan Afzan, Kuantan, within an area of eastern Peninsular Malaysia. We assessed the rate and distribution of HCV genotypes during two consecutive periods, from 2005 to 2006 and from 2013 to 2014, according to age, gender, race and risk factors. Results: There were more male, Malay ethnic and IDU patients seen in the latter cohort. Genotype 3 was the dominant genotype followed by genotype 1, 4 and 6. Statistical evaluation of the demographics of HCV patients stratified by genotypes did not reveal any significant difference between the two periods. There was no association between the risk factors analyzed and the acquisition of different HCV genotypes. However, there was significant difference between males and patients receiving treatment in the second cohort (p<0.005). Conclusion: The genotype distribution remains similar although there was a trend towards having slightly more genotype 3 in the latter years. The proportions of male patients and patients receiving treatment in the latter period were significantly higher. The Faculty of Medicine, International Islamic University Malaysia 2015 Article PeerReviewed application/pdf en http://irep.iium.edu.my/50719/1/50719_-_Distribution_pattern_of_hepatitis_c_virus_in_eastern_peninsular_malaysia_for_the_past_decade.pdf H.M, Hadzr and Tee, Hoi Poh and Che Aun, Azlida (2015) Distribution pattern of hepatitis c virus in eastern peninsular malaysia for the past decade. The International Medical Journal Malaysia, 14 (Supp). p. 3. ISSN 1823-4631 http://iiumedic.net/imjm/v1/volume-14-supplement/
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RC Internal medicine
spellingShingle	RC Internal medicine H.M, Hadzr Tee, Hoi Poh Che Aun, Azlida Distribution pattern of hepatitis c virus in eastern peninsular malaysia for the past decade
description	Introduction: Analysis of the Hepatitis C Virus’ (HCV) genotypic spread in a particular area has a crucial impact on public health. Genotyping is essential before initiating treatment. Methodology: This is a hospital-based cohort of 133 chronic hepatitis C patients, collected prospectively among subjects attending Hospital Tengku Ampuan Afzan, Kuantan, within an area of eastern Peninsular Malaysia. We assessed the rate and distribution of HCV genotypes during two consecutive periods, from 2005 to 2006 and from 2013 to 2014, according to age, gender, race and risk factors. Results: There were more male, Malay ethnic and IDU patients seen in the latter cohort. Genotype 3 was the dominant genotype followed by genotype 1, 4 and 6. Statistical evaluation of the demographics of HCV patients stratified by genotypes did not reveal any significant difference between the two periods. There was no association between the risk factors analyzed and the acquisition of different HCV genotypes. However, there was significant difference between males and patients receiving treatment in the second cohort (p<0.005). Conclusion: The genotype distribution remains similar although there was a trend towards having slightly more genotype 3 in the latter years. The proportions of male patients and patients receiving treatment in the latter period were significantly higher.
format	Article
author	H.M, Hadzr Tee, Hoi Poh Che Aun, Azlida
author_facet	H.M, Hadzr Tee, Hoi Poh Che Aun, Azlida
author_sort	H.M, Hadzr
title	Distribution pattern of hepatitis c virus in eastern peninsular malaysia for the past decade
title_short	Distribution pattern of hepatitis c virus in eastern peninsular malaysia for the past decade
title_full	Distribution pattern of hepatitis c virus in eastern peninsular malaysia for the past decade
title_fullStr	Distribution pattern of hepatitis c virus in eastern peninsular malaysia for the past decade
title_full_unstemmed	Distribution pattern of hepatitis c virus in eastern peninsular malaysia for the past decade
title_sort	distribution pattern of hepatitis c virus in eastern peninsular malaysia for the past decade
publisher	The Faculty of Medicine, International Islamic University Malaysia
publishDate	2015
url	http://irep.iium.edu.my/50719/ http://irep.iium.edu.my/50719/ http://irep.iium.edu.my/50719/1/50719_-_Distribution_pattern_of_hepatitis_c_virus_in_eastern_peninsular_malaysia_for_the_past_decade.pdf
first_indexed	2023-09-18T21:11:43Z
last_indexed	2023-09-18T21:11:43Z
_version_	1777411297236746240

Distribution pattern of hepatitis c virus in eastern peninsular malaysia for the past decade

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