Antifungal activity of Eurycoma longifolia jack (Tongkat Ali) root extract
Eurycoma longifolia jack (Tongkat Ali) has been known to possess many important biological properties and its uses are gradually expanding . To test the presence of antifungal activity of the ethanolic Eurycoma longifolia Jack (E.L) root extract. E.L. roots were extracted using ethanol . Two type...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English English |
| Published: |
Ectodermal Dysplasia Group-Turkey
2016
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/50981/ http://irep.iium.edu.my/50981/ http://irep.iium.edu.my/50981/1/Antifungal_activity_of_eurycoma_longifolia_root_extract.pdf http://irep.iium.edu.my/50981/4/50981_Antifungal%20activity_scopus.pdf |
| Summary: | Eurycoma longifolia jack (Tongkat Ali) has been known to possess many important biological
properties and its uses are gradually expanding . To test the presence of antifungal activity of the
ethanolic Eurycoma longifolia Jack (E.L) root extract. E.L. roots were extracted using ethanol . Two
types of fungal strains were used; Candida albicans and Aspergillus fumigatus. Disc diffusion assay
and Minimum inhibitory concentration (MIC) tests were used to determine the antifungal activity.
The extract was prepared into three concentrations of 50, 100 and 150 mg/ml, Nystatin was used
as positive control. The ethanolic extract of E. longifolia Jack root showed positive antifungal activity
against C.albicans and A.fumigatus. The antifungal activity, measured through the zone of growth
inhibition on the agar disc diffusion assay, against A.fumigatus was recorded to be 3.78±0.63,
6.11±1.45, 9.89±0.74mm, while for C.albicans was 4.44±0.5, 6.56±0.50, 8.44±0.90 mm for the
extract concentrations of 50, 100 and 150 mg/ml respectively. The results of MIC showed the
inhibition of visible growth of A.fumigatus and C.albicans at the minimum concentration of 12.5
and 25 mg/ml respectively. E.L root extract possesses potent antifungal properties and has the
potential to be used as a medicinal product. |
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