A study on rheological properties of various gelling agents for topical applications

A sum of 26 gels were prepared, each with different materials of gelling agent. All 26 gelling agent materials was prepared with the same concentration of 3% w/w, and added with 5% w/w propylene glycol as solubilizer, 0.1% w/w methyl paraben, and 0.03%w/w propyl paraben as preservatives. A standard...

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Main Authors: Abdul Rahman, Mohammad Nasrin, Abdul Qader, Omar Abdul Jabbar, Sukmasari, Susi, Ibrahim, Mohammad, Ismail, Ahmad Faisal, Doolaanea, Abd Almonem
Format: Conference or Workshop Item
Language:English
English
Published: 2016
Subjects:
Online Access:http://irep.iium.edu.my/51638/
http://irep.iium.edu.my/51638/
http://irep.iium.edu.my/51638/1/51638_poster.pdf
http://irep.iium.edu.my/51638/2/51638_A_Study_on_Rheological_Properties.pdf
id iium-51638
recordtype eprints
spelling iium-516382018-05-22T00:57:43Z http://irep.iium.edu.my/51638/ A study on rheological properties of various gelling agents for topical applications Abdul Rahman, Mohammad Nasrin Abdul Qader, Omar Abdul Jabbar Sukmasari, Susi Ibrahim, Mohammad Ismail, Ahmad Faisal Doolaanea, Abd Almonem RK Dentistry RS Pharmacy and materia medica A sum of 26 gels were prepared, each with different materials of gelling agent. All 26 gelling agent materials was prepared with the same concentration of 3% w/w, and added with 5% w/w propylene glycol as solubilizer, 0.1% w/w methyl paraben, and 0.03%w/w propyl paraben as preservatives. A standard 3% gel concentration was prepared for each of the gelling agents, and all other procedure was kept constant. The gels were then analysed using Rheometer to compare their rheological properties. There are 3 screening phase where initially, each of the gels were analysed using creep test to study their Shear stress, shear rates, and viscosity profiles. If they show an acceptable pseudoplastic material, stress sweep test were then conducted to study the stability of the gels in a range of stress applied. If that particular gel has linear viscoelastic region, frequency sweep test is conducted to confirm its stability profiles. There are 15 gels having good pseudoplastic rheology properties. These15 gelling agents were tested with stress sweep and frequency sweep test. Lastly, only 3 gels were screened to have stable linear viscoelastic range with stress and frequency sweep test. All the rheological properties were well documented for each of the gelling agents. 2016-08-15 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/51638/1/51638_poster.pdf application/pdf en http://irep.iium.edu.my/51638/2/51638_A_Study_on_Rheological_Properties.pdf Abdul Rahman, Mohammad Nasrin and Abdul Qader, Omar Abdul Jabbar and Sukmasari, Susi and Ibrahim, Mohammad and Ismail, Ahmad Faisal and Doolaanea, Abd Almonem (2016) A study on rheological properties of various gelling agents for topical applications. In: 2nd International Conference on Industrial Pharmacy (ICIP 2016), 15th-16th Aug. 2016, Kuantan, Pahang. (Unpublished) http://www.iium.edu.my/icip2016/
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
English
topic RK Dentistry
RS Pharmacy and materia medica
spellingShingle RK Dentistry
RS Pharmacy and materia medica
Abdul Rahman, Mohammad Nasrin
Abdul Qader, Omar Abdul Jabbar
Sukmasari, Susi
Ibrahim, Mohammad
Ismail, Ahmad Faisal
Doolaanea, Abd Almonem
A study on rheological properties of various gelling agents for topical applications
description A sum of 26 gels were prepared, each with different materials of gelling agent. All 26 gelling agent materials was prepared with the same concentration of 3% w/w, and added with 5% w/w propylene glycol as solubilizer, 0.1% w/w methyl paraben, and 0.03%w/w propyl paraben as preservatives. A standard 3% gel concentration was prepared for each of the gelling agents, and all other procedure was kept constant. The gels were then analysed using Rheometer to compare their rheological properties. There are 3 screening phase where initially, each of the gels were analysed using creep test to study their Shear stress, shear rates, and viscosity profiles. If they show an acceptable pseudoplastic material, stress sweep test were then conducted to study the stability of the gels in a range of stress applied. If that particular gel has linear viscoelastic region, frequency sweep test is conducted to confirm its stability profiles. There are 15 gels having good pseudoplastic rheology properties. These15 gelling agents were tested with stress sweep and frequency sweep test. Lastly, only 3 gels were screened to have stable linear viscoelastic range with stress and frequency sweep test. All the rheological properties were well documented for each of the gelling agents.
format Conference or Workshop Item
author Abdul Rahman, Mohammad Nasrin
Abdul Qader, Omar Abdul Jabbar
Sukmasari, Susi
Ibrahim, Mohammad
Ismail, Ahmad Faisal
Doolaanea, Abd Almonem
author_facet Abdul Rahman, Mohammad Nasrin
Abdul Qader, Omar Abdul Jabbar
Sukmasari, Susi
Ibrahim, Mohammad
Ismail, Ahmad Faisal
Doolaanea, Abd Almonem
author_sort Abdul Rahman, Mohammad Nasrin
title A study on rheological properties of various gelling agents for topical applications
title_short A study on rheological properties of various gelling agents for topical applications
title_full A study on rheological properties of various gelling agents for topical applications
title_fullStr A study on rheological properties of various gelling agents for topical applications
title_full_unstemmed A study on rheological properties of various gelling agents for topical applications
title_sort study on rheological properties of various gelling agents for topical applications
publishDate 2016
url http://irep.iium.edu.my/51638/
http://irep.iium.edu.my/51638/
http://irep.iium.edu.my/51638/1/51638_poster.pdf
http://irep.iium.edu.my/51638/2/51638_A_Study_on_Rheological_Properties.pdf
first_indexed 2023-09-18T21:13:08Z
last_indexed 2023-09-18T21:13:08Z
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