Prevalence of thyroid dysfunction in East and West Coast of Malaysia

Objectives. To determine the prevalence of thyroid dysfunction in the coastal communities of Malaysia. This study is part of a nationwide study looking into the prevalence of thyroid disorders. Methods. A cross sectional study was performed in Tanjong Karang and Kuala Selangor, Selangor - two co...

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Main Authors:	Shahar, Mohammad Arif, Saud Gany, Siti Liyana, Omar, Ahmad Marzuki, Abdul Wahab, Norasyikin, Sukor, Norlela, Kamaruddin, Nor Azmi
Format:	Conference or Workshop Item
Language:	English
Published:	Malaysian Endocrine & Metabolic Society 2016
Subjects:	RC Internal medicine
Online Access:	http://irep.iium.edu.my/52069/ http://irep.iium.edu.my/52069/1/prevalecne%20of%20thyroid%20dysfunction%20in%20east%20and%20west%20coast%20of%20malaysia.pdf

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recordtype	eprints
spelling	iium-520692016-10-17T02:09:49Z http://irep.iium.edu.my/52069/ Prevalence of thyroid dysfunction in East and West Coast of Malaysia Shahar, Mohammad Arif Saud Gany, Siti Liyana Omar, Ahmad Marzuki Abdul Wahab, Norasyikin Sukor, Norlela Kamaruddin, Nor Azmi RC Internal medicine Objectives. To determine the prevalence of thyroid dysfunction in the coastal communities of Malaysia. This study is part of a nationwide study looking into the prevalence of thyroid disorders. Methods. A cross sectional study was performed in Tanjong Karang and Kuala Selangor, Selangor - two coastal villages in rural West Coast (WC) and Kuantan, Pahang - a city in the East Coast (EC) of Malaysia. A participant from each household from each villages/city was selected using KISH tables. Sociodemographic data, medical history, anthropometric measurements were recorded. Blood withdrawn was tested for thyroid function test. Serum thyroid stimulating hormone (TSH) was measured using a third generation chemiluminescent immunoassay with a detection limit of 0.01 mIU/L. TSH level of less than 0.32 mIU/L was considered hyperthyroid. Hypothyroidism was defined as TSH level of more than 5.00 mIU/L. Results. A total of 904 subjects were recruited with a mean age of 46.3 ± 16.3 years. Majority were Malays (88.0%), followed by Indians (7.7%) and Chinese (3.7%). Four hundred and fifteen (415) respondents were from the WC community and 489 respondents were from the EC community. The respondents from the EC was significantly younger compared to those from the WC (54.1 ± 14.1 versus 39.6 ± 15.1 years, p < 0.001). A total of 895 blood samples were available for thyroid level assessment. The prevalence of overt and subclinical hypothyroidism in both coastal communities was 3.4 and 13.4 per 1000 population respectively. On the other hand, the prevalence of overt and subclinical hyperthyroidism was 3.4 and 26.8 per 1000 population respectively. There was no significant difference between the prevalence of thyroid dysfunction between the WC and EC population. Overall, female has higher prevalence of thyroid dysfunction compared to male in both areas. Conclusion. The prevalence of overt hyperthyroidism and hypothyroidism was 3.4 per 1000 population each. The low prevalence of thyroid dysfunction in the West and East Coast communities could be attributed to the iodine sufficient status in those areas. Malaysian Endocrine & Metabolic Society 2016-05-19 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/52069/1/prevalecne%20of%20thyroid%20dysfunction%20in%20east%20and%20west%20coast%20of%20malaysia.pdf Shahar, Mohammad Arif and Saud Gany, Siti Liyana and Omar, Ahmad Marzuki and Abdul Wahab, Norasyikin and Sukor, Norlela and Kamaruddin, Nor Azmi (2016) Prevalence of thyroid dysfunction in East and West Coast of Malaysia. In: 7th MEMS Annual Congress, 19-22 May 2016, Kuala Lumpur.
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RC Internal medicine
spellingShingle	RC Internal medicine Shahar, Mohammad Arif Saud Gany, Siti Liyana Omar, Ahmad Marzuki Abdul Wahab, Norasyikin Sukor, Norlela Kamaruddin, Nor Azmi Prevalence of thyroid dysfunction in East and West Coast of Malaysia
description	Objectives. To determine the prevalence of thyroid dysfunction in the coastal communities of Malaysia. This study is part of a nationwide study looking into the prevalence of thyroid disorders. Methods. A cross sectional study was performed in Tanjong Karang and Kuala Selangor, Selangor - two coastal villages in rural West Coast (WC) and Kuantan, Pahang - a city in the East Coast (EC) of Malaysia. A participant from each household from each villages/city was selected using KISH tables. Sociodemographic data, medical history, anthropometric measurements were recorded. Blood withdrawn was tested for thyroid function test. Serum thyroid stimulating hormone (TSH) was measured using a third generation chemiluminescent immunoassay with a detection limit of 0.01 mIU/L. TSH level of less than 0.32 mIU/L was considered hyperthyroid. Hypothyroidism was defined as TSH level of more than 5.00 mIU/L. Results. A total of 904 subjects were recruited with a mean age of 46.3 ± 16.3 years. Majority were Malays (88.0%), followed by Indians (7.7%) and Chinese (3.7%). Four hundred and fifteen (415) respondents were from the WC community and 489 respondents were from the EC community. The respondents from the EC was significantly younger compared to those from the WC (54.1 ± 14.1 versus 39.6 ± 15.1 years, p < 0.001). A total of 895 blood samples were available for thyroid level assessment. The prevalence of overt and subclinical hypothyroidism in both coastal communities was 3.4 and 13.4 per 1000 population respectively. On the other hand, the prevalence of overt and subclinical hyperthyroidism was 3.4 and 26.8 per 1000 population respectively. There was no significant difference between the prevalence of thyroid dysfunction between the WC and EC population. Overall, female has higher prevalence of thyroid dysfunction compared to male in both areas. Conclusion. The prevalence of overt hyperthyroidism and hypothyroidism was 3.4 per 1000 population each. The low prevalence of thyroid dysfunction in the West and East Coast communities could be attributed to the iodine sufficient status in those areas.
format	Conference or Workshop Item
author	Shahar, Mohammad Arif Saud Gany, Siti Liyana Omar, Ahmad Marzuki Abdul Wahab, Norasyikin Sukor, Norlela Kamaruddin, Nor Azmi
author_facet	Shahar, Mohammad Arif Saud Gany, Siti Liyana Omar, Ahmad Marzuki Abdul Wahab, Norasyikin Sukor, Norlela Kamaruddin, Nor Azmi
author_sort	Shahar, Mohammad Arif
title	Prevalence of thyroid dysfunction in East and West Coast of Malaysia
title_short	Prevalence of thyroid dysfunction in East and West Coast of Malaysia
title_full	Prevalence of thyroid dysfunction in East and West Coast of Malaysia
title_fullStr	Prevalence of thyroid dysfunction in East and West Coast of Malaysia
title_full_unstemmed	Prevalence of thyroid dysfunction in East and West Coast of Malaysia
title_sort	prevalence of thyroid dysfunction in east and west coast of malaysia
publisher	Malaysian Endocrine & Metabolic Society
publishDate	2016
url	http://irep.iium.edu.my/52069/ http://irep.iium.edu.my/52069/1/prevalecne%20of%20thyroid%20dysfunction%20in%20east%20and%20west%20coast%20of%20malaysia.pdf
first_indexed	2023-09-18T21:13:50Z
last_indexed	2023-09-18T21:13:50Z
_version_	1777411430301040640

Prevalence of thyroid dysfunction in East and West Coast of Malaysia

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