Prevalence of elevated aldosterone renin ratio in three main states of Peninsular Malaysia
Objective: The objective of this study was to determine the prevalence of increased Aldosterone Renin Ratio (ARR) in parts of Selangor, Perak and Pahang. Methods: This was a cross sectional study involving subjects in Selangor, Perak and Pahang. The World Health Survey Kish tables were used to se...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , |
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| Format: | Conference or Workshop Item |
| Language: | English |
| Published: |
Malaysian Endocrine & Metabolic Society (MEMS)
2016
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/52077/ http://irep.iium.edu.my/52077/1/prevalence%20of%20raised%20ARR%20in%203%20states.pdf |
| Summary: | Objective: The objective of this study was to determine the prevalence of increased Aldosterone Renin Ratio (ARR) in parts of Selangor, Perak and Pahang.
Methods: This was a cross sectional study involving subjects in Selangor, Perak and Pahang. The World Health Survey Kish tables were used to select eligible subjects (≥18 years old) from each household. Their social demography, past medical history, anthropometric measurement and blood pressure were recorded.
Blood were withdrawn for Aldosterone (ALD), Plasma Renin Activity (PRA), Creatinine (creat) and potassium (K). Raised ARR is defined as aldosterone/renin ratio of more than 20.
Results: A total of 1073 subjects (age 50 +/- 16.4). One hundred and nineteen (11.1%) subjects showed an ARR =/> 20. Forty nine (41.2%) out of the elevated ARR =/> 20 were hypertensive, 11 of which were not taking any anti-hypertensive drugs and 54 subjects (45.4%) were normotensive. Only 7 (5.9%) of them were hypokalemic, one of them being hypertensive. The main clinical characteristics of subjects with raised ARR are shown in Table 1.
Conclusion: The prevalence of raised ARR in Rural Selangor was 11.1%, and only 5.9% of them were hypokalemic. |
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