Prevalence, clinical features and factors associated with psychosis among Idiopathic Parkinson’s disease (IPD) patients in Universiti Kebangsaan Malaysia Medical Centre (UKMMC)

Intro: This was a cross sectional study of the prevalence of psychosis and its characteristic in patients with Idiopathic PD (IPD) attending neurology clinic, Pusat Perubatan Universiti Kebangsaan Malaysia (PPUKM). Methods: Assessment were done using a structured demographic data and clinical...

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Main Authors:	Md Rosli, Najwa Hanim, Abdul Rahman, Abdul Hamid, Mohamed Ibrahim, Norlinah
Format:	Conference or Workshop Item
Language:	English
Published:	2016
Subjects:	R Medicine (General)
Online Access:	http://irep.iium.edu.my/52218/ http://irep.iium.edu.my/52218/ http://irep.iium.edu.my/52218/1/52218_Prevalence%2C%20clinical%20features.pdf

id	iium-52218
recordtype	eprints
spelling	iium-522182018-05-24T03:39:26Z http://irep.iium.edu.my/52218/ Prevalence, clinical features and factors associated with psychosis among Idiopathic Parkinson’s disease (IPD) patients in Universiti Kebangsaan Malaysia Medical Centre (UKMMC) Md Rosli, Najwa Hanim Abdul Rahman, Abdul Hamid Mohamed Ibrahim, Norlinah R Medicine (General) Intro: This was a cross sectional study of the prevalence of psychosis and its characteristic in patients with Idiopathic PD (IPD) attending neurology clinic, Pusat Perubatan Universiti Kebangsaan Malaysia (PPUKM). Methods: Assessment were done using a structured demographic data and clinical information questionnaire, Mini-International Neuropsychiatric Interview (MINI) 6.0.0, Starkstein’s Apathy Scale (AS), Mini Mental State Examination (MMSE), Movement Disorder Society – Unified Parkinson Disease Rating Scale (MDS-UPDRS) Q1-Q6, Hoehn and Yahr (H&Y) stages of PD and Schwab and England Activities of Daily Living (ADL) scale. Results: 112 patients were studied. Psychosis was identified in 39 (34.8 %) patients (33 patients with hallucination only, 6 with hallucination and delusion (psychotic disorder) and none with delusions only). Among patients experiencing hallucinations, 14 (35.9%) had visual hallucination only, 12 (30.8%) had auditory hallucinations only, and 13 (33.3%) had both visual and auditory hallucinations. Psychosis were more common in IPD patients with cognitive impairment using MDSQ1 scoring (OR 0.15; 95% CI, 0.05-0.63; P = p‹0.05) while others variables were not significant. The analysis between patients with psychotic symptoms only and patients with psychotic disorder showed education level (p<0.05), duration of illness (OR 1.8; 95% CI, (-10.7 - -3.5; p <0.01), cognitive impairment score - MDSQ1 (OR 0.2; 95% CI, 0.2-0.9; p<0.01), H&Y score (OR 0.4; 95% CI, -2.1- -0.6; p<0.01) and ADL score (OR 0.6; 95% CI,0.3 – 2.6; p<0.05) were significant. Conclusion: Lower education level, longer duration of illness, more advance stage of Parkinson disease and less functioning in ADL were significant in psychotic disorder in IPD. 2016 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/52218/1/52218_Prevalence%2C%20clinical%20features.pdf Md Rosli, Najwa Hanim and Abdul Rahman, Abdul Hamid and Mohamed Ibrahim, Norlinah (2016) Prevalence, clinical features and factors associated with psychosis among Idiopathic Parkinson’s disease (IPD) patients in Universiti Kebangsaan Malaysia Medical Centre (UKMMC). In: Medical Research Symposium & Pacific Partnership in conjunction with Kuantan Research Day 2016, 3rd-5th August 2016, Kuantan, Pahang. (Unpublished) http://iiumedic.net/web/events/mrs2016/
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	R Medicine (General)
spellingShingle	R Medicine (General) Md Rosli, Najwa Hanim Abdul Rahman, Abdul Hamid Mohamed Ibrahim, Norlinah Prevalence, clinical features and factors associated with psychosis among Idiopathic Parkinson’s disease (IPD) patients in Universiti Kebangsaan Malaysia Medical Centre (UKMMC)
description	Intro: This was a cross sectional study of the prevalence of psychosis and its characteristic in patients with Idiopathic PD (IPD) attending neurology clinic, Pusat Perubatan Universiti Kebangsaan Malaysia (PPUKM). Methods: Assessment were done using a structured demographic data and clinical information questionnaire, Mini-International Neuropsychiatric Interview (MINI) 6.0.0, Starkstein’s Apathy Scale (AS), Mini Mental State Examination (MMSE), Movement Disorder Society – Unified Parkinson Disease Rating Scale (MDS-UPDRS) Q1-Q6, Hoehn and Yahr (H&Y) stages of PD and Schwab and England Activities of Daily Living (ADL) scale. Results: 112 patients were studied. Psychosis was identified in 39 (34.8 %) patients (33 patients with hallucination only, 6 with hallucination and delusion (psychotic disorder) and none with delusions only). Among patients experiencing hallucinations, 14 (35.9%) had visual hallucination only, 12 (30.8%) had auditory hallucinations only, and 13 (33.3%) had both visual and auditory hallucinations. Psychosis were more common in IPD patients with cognitive impairment using MDSQ1 scoring (OR 0.15; 95% CI, 0.05-0.63; P = p‹0.05) while others variables were not significant. The analysis between patients with psychotic symptoms only and patients with psychotic disorder showed education level (p<0.05), duration of illness (OR 1.8; 95% CI, (-10.7 - -3.5; p <0.01), cognitive impairment score - MDSQ1 (OR 0.2; 95% CI, 0.2-0.9; p<0.01), H&Y score (OR 0.4; 95% CI, -2.1- -0.6; p<0.01) and ADL score (OR 0.6; 95% CI,0.3 – 2.6; p<0.05) were significant. Conclusion: Lower education level, longer duration of illness, more advance stage of Parkinson disease and less functioning in ADL were significant in psychotic disorder in IPD.
format	Conference or Workshop Item
author	Md Rosli, Najwa Hanim Abdul Rahman, Abdul Hamid Mohamed Ibrahim, Norlinah
author_facet	Md Rosli, Najwa Hanim Abdul Rahman, Abdul Hamid Mohamed Ibrahim, Norlinah
author_sort	Md Rosli, Najwa Hanim
title	Prevalence, clinical features and factors associated with psychosis among Idiopathic Parkinson’s disease (IPD) patients in Universiti Kebangsaan Malaysia Medical Centre (UKMMC)
title_short	Prevalence, clinical features and factors associated with psychosis among Idiopathic Parkinson’s disease (IPD) patients in Universiti Kebangsaan Malaysia Medical Centre (UKMMC)
title_full	Prevalence, clinical features and factors associated with psychosis among Idiopathic Parkinson’s disease (IPD) patients in Universiti Kebangsaan Malaysia Medical Centre (UKMMC)
title_fullStr	Prevalence, clinical features and factors associated with psychosis among Idiopathic Parkinson’s disease (IPD) patients in Universiti Kebangsaan Malaysia Medical Centre (UKMMC)
title_full_unstemmed	Prevalence, clinical features and factors associated with psychosis among Idiopathic Parkinson’s disease (IPD) patients in Universiti Kebangsaan Malaysia Medical Centre (UKMMC)
title_sort	prevalence, clinical features and factors associated with psychosis among idiopathic parkinson’s disease (ipd) patients in universiti kebangsaan malaysia medical centre (ukmmc)
publishDate	2016
url	http://irep.iium.edu.my/52218/ http://irep.iium.edu.my/52218/ http://irep.iium.edu.my/52218/1/52218_Prevalence%2C%20clinical%20features.pdf
first_indexed	2023-09-18T21:14:00Z
last_indexed	2023-09-18T21:14:00Z
_version_	1777411440822452224

Prevalence, clinical features and factors associated with psychosis among Idiopathic Parkinson’s disease (IPD) patients in Universiti Kebangsaan Malaysia Medical Centre (UKMMC)

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