Effect of different drying treatments and solvent ratios on phytochemical constituents of ipomoea aquatica and correlation with α-glucosidase inhibitory activity

Ipomoea aquatica is an aquatic plant that is widely consumed in Southeast Asia as a vegetable. In this study, the influence of various ethanol ratios (0, 20, 50, 80, and 100%) as an extraction solvent and different drying methods including air drying (AD), sun drying (SD) and oven drying (OD) on phy...

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Main Authors:	Abu Bakar Sajak, Azliana, Abas, Faridah, Ismail, Amin, Khatib, Alfi
Format:	Article
Language:	English English English
Published:	2016
Subjects:	QD Chemistry
Online Access:	http://irep.iium.edu.my/53531/ http://irep.iium.edu.my/53531/ http://irep.iium.edu.my/53531/1/sajak2016.pdf http://irep.iium.edu.my/53531/7/53531_Effect%20of%20Different%20Drying%20Treatments%20and%20Solvent%20Ratios_Scopus.pdf http://irep.iium.edu.my/53531/8/53531_Effect%20of%20different%20drying%20treatments%20and%20solvent%20ratios_WoS.pdf

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recordtype	eprints
spelling	iium-535312017-10-04T00:26:59Z http://irep.iium.edu.my/53531/ Effect of different drying treatments and solvent ratios on phytochemical constituents of ipomoea aquatica and correlation with α-glucosidase inhibitory activity Abu Bakar Sajak, Azliana Abas, Faridah Ismail, Amin Khatib, Alfi QD Chemistry Ipomoea aquatica is an aquatic plant that is widely consumed in Southeast Asia as a vegetable. In this study, the influence of various ethanol ratios (0, 20, 50, 80, and 100%) as an extraction solvent and different drying methods including air drying (AD), sun drying (SD) and oven drying (OD) on phytochemical constituents of I. aquatica was investigated using a proton nuclear magnetic resonance (1H NMR) based metabolomics approach. The effect on αglucosidase inhibitory activity and total phenolic content (TPC) was also examined. Clear discrimination was observed between different ethanol ratios and different drying processes by principal component analysis (PCA). The highest α-glucosidase inhibitory activity was observed for absolute ethanol extract from the OD method with IC50 value of 204.0 ± 59.0 µg/mL and TPC value of 22.0 ± 0.7 µg GAE/mg extract. Correlation between the α-glucosidase inhibitory activity and the metabolite were analyzed using a partial least square (PLS) analysis. The metabolites that are responsible for the activity were quercetin derivatives, chlorogenic acid derivatives, sucrose and fructose. This study highlights the basis for future investigations of I. aquatica as a source of food that has the potential for nutraceutical enhancement and as ingredient in medicinal preparation. 2016 Article PeerReviewed application/pdf en http://irep.iium.edu.my/53531/1/sajak2016.pdf application/pdf en http://irep.iium.edu.my/53531/7/53531_Effect%20of%20Different%20Drying%20Treatments%20and%20Solvent%20Ratios_Scopus.pdf application/pdf en http://irep.iium.edu.my/53531/8/53531_Effect%20of%20different%20drying%20treatments%20and%20solvent%20ratios_WoS.pdf Abu Bakar Sajak, Azliana and Abas, Faridah and Ismail, Amin and Khatib, Alfi (2016) Effect of different drying treatments and solvent ratios on phytochemical constituents of ipomoea aquatica and correlation with α-glucosidase inhibitory activity. International Journal of Food Properties, 19 (12). pp. 2817-2831. ISSN 1094-2912 E-ISSN 1532-2386 10.1080/10942912.2016.1141295
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English English
topic	QD Chemistry
spellingShingle	QD Chemistry Abu Bakar Sajak, Azliana Abas, Faridah Ismail, Amin Khatib, Alfi Effect of different drying treatments and solvent ratios on phytochemical constituents of ipomoea aquatica and correlation with α-glucosidase inhibitory activity
description	Ipomoea aquatica is an aquatic plant that is widely consumed in Southeast Asia as a vegetable. In this study, the influence of various ethanol ratios (0, 20, 50, 80, and 100%) as an extraction solvent and different drying methods including air drying (AD), sun drying (SD) and oven drying (OD) on phytochemical constituents of I. aquatica was investigated using a proton nuclear magnetic resonance (1H NMR) based metabolomics approach. The effect on αglucosidase inhibitory activity and total phenolic content (TPC) was also examined. Clear discrimination was observed between different ethanol ratios and different drying processes by principal component analysis (PCA). The highest α-glucosidase inhibitory activity was observed for absolute ethanol extract from the OD method with IC50 value of 204.0 ± 59.0 µg/mL and TPC value of 22.0 ± 0.7 µg GAE/mg extract. Correlation between the α-glucosidase inhibitory activity and the metabolite were analyzed using a partial least square (PLS) analysis. The metabolites that are responsible for the activity were quercetin derivatives, chlorogenic acid derivatives, sucrose and fructose. This study highlights the basis for future investigations of I. aquatica as a source of food that has the potential for nutraceutical enhancement and as ingredient in medicinal preparation.
format	Article
author	Abu Bakar Sajak, Azliana Abas, Faridah Ismail, Amin Khatib, Alfi
author_facet	Abu Bakar Sajak, Azliana Abas, Faridah Ismail, Amin Khatib, Alfi
author_sort	Abu Bakar Sajak, Azliana
title	Effect of different drying treatments and solvent ratios on phytochemical constituents of ipomoea aquatica and correlation with α-glucosidase inhibitory activity
title_short	Effect of different drying treatments and solvent ratios on phytochemical constituents of ipomoea aquatica and correlation with α-glucosidase inhibitory activity
title_full	Effect of different drying treatments and solvent ratios on phytochemical constituents of ipomoea aquatica and correlation with α-glucosidase inhibitory activity
title_fullStr	Effect of different drying treatments and solvent ratios on phytochemical constituents of ipomoea aquatica and correlation with α-glucosidase inhibitory activity
title_full_unstemmed	Effect of different drying treatments and solvent ratios on phytochemical constituents of ipomoea aquatica and correlation with α-glucosidase inhibitory activity
title_sort	effect of different drying treatments and solvent ratios on phytochemical constituents of ipomoea aquatica and correlation with α-glucosidase inhibitory activity
publishDate	2016
url	http://irep.iium.edu.my/53531/ http://irep.iium.edu.my/53531/ http://irep.iium.edu.my/53531/1/sajak2016.pdf http://irep.iium.edu.my/53531/7/53531_Effect%20of%20Different%20Drying%20Treatments%20and%20Solvent%20Ratios_Scopus.pdf http://irep.iium.edu.my/53531/8/53531_Effect%20of%20different%20drying%20treatments%20and%20solvent%20ratios_WoS.pdf
first_indexed	2023-09-18T21:15:43Z
last_indexed	2023-09-18T21:15:43Z
_version_	1777411548124282880

Effect of different drying treatments and solvent ratios on phytochemical constituents of ipomoea aquatica and correlation with α-glucosidase inhibitory activity

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