The effects of Ficus auriculata (fig) on cell cycle profile and apoptosis activity of Human lung adenocarcinoma cells, A549

Ficus auriculata (fig) has an immense value of benefits with regards to their medicinal and therapeutic properties. (Fig) has been long used in traditional folk medicine, Traditional Chinese Medicine (TCM) and Ayurveda. Many scientific researches have proven the usage of this natural medicine in in...

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Main Authors:	Jamil, Elyna Fatini, Abdul Ghani, Radiah
Format:	Conference or Workshop Item
Language:	English
Published:	2016
Subjects:	RB Pathology
Online Access:	http://irep.iium.edu.my/53656/ http://irep.iium.edu.my/53656/ http://irep.iium.edu.my/53656/1/53656_The%20effects%20of%20Ficus%20auriculata.pdf

id	iium-53656
recordtype	eprints
spelling	iium-536562017-02-14T06:24:40Z http://irep.iium.edu.my/53656/ The effects of Ficus auriculata (fig) on cell cycle profile and apoptosis activity of Human lung adenocarcinoma cells, A549 Jamil, Elyna Fatini Abdul Ghani, Radiah RB Pathology Ficus auriculata (fig) has an immense value of benefits with regards to their medicinal and therapeutic properties. (Fig) has been long used in traditional folk medicine, Traditional Chinese Medicine (TCM) and Ayurveda. Many scientific researches have proven the usage of this natural medicine in in vitro and in vivo studies, where anti-cancer is among of its recognized properties. To acquire further details on how F.auriculata (fig) inhibited cancer growth, we investigated the effects of its exposure on cell cycle profile. Subsequently we determined the type of cell death and the mechanism it induced using flow cytometer. Human lung adenocarcinoma cell line A549 was selected as the model of this study. Results indicated significant decreased of A549 cells in G0/G1 and concurrent accumulation of cells in G2/M phase. Cell death analysis revealed significant late apoptosis induced by F.auriculata (fig) via caspase independent pathway. Therefore, we concluded that F.auriculata (fig) is one of the promising natural medicines that can be used as cancer preventive strategy, as a result from its effects against cell cycle profile and apoptosis via caspase independent pathway. 2016-12-07 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/53656/1/53656_The%20effects%20of%20Ficus%20auriculata.pdf Jamil, Elyna Fatini and Abdul Ghani, Radiah (2016) The effects of Ficus auriculata (fig) on cell cycle profile and apoptosis activity of Human lung adenocarcinoma cells, A549. In: 3rd Pan-Asian Biomedical Science Conference 2016 Kuala Lumpur, 7th–8th Dec. 2016, Kuala Lumpur. (Unpublished) https://sites.google.com/site/3rdpabsc2016/
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RB Pathology
spellingShingle	RB Pathology Jamil, Elyna Fatini Abdul Ghani, Radiah The effects of Ficus auriculata (fig) on cell cycle profile and apoptosis activity of Human lung adenocarcinoma cells, A549
description	Ficus auriculata (fig) has an immense value of benefits with regards to their medicinal and therapeutic properties. (Fig) has been long used in traditional folk medicine, Traditional Chinese Medicine (TCM) and Ayurveda. Many scientific researches have proven the usage of this natural medicine in in vitro and in vivo studies, where anti-cancer is among of its recognized properties. To acquire further details on how F.auriculata (fig) inhibited cancer growth, we investigated the effects of its exposure on cell cycle profile. Subsequently we determined the type of cell death and the mechanism it induced using flow cytometer. Human lung adenocarcinoma cell line A549 was selected as the model of this study. Results indicated significant decreased of A549 cells in G0/G1 and concurrent accumulation of cells in G2/M phase. Cell death analysis revealed significant late apoptosis induced by F.auriculata (fig) via caspase independent pathway. Therefore, we concluded that F.auriculata (fig) is one of the promising natural medicines that can be used as cancer preventive strategy, as a result from its effects against cell cycle profile and apoptosis via caspase independent pathway.
format	Conference or Workshop Item
author	Jamil, Elyna Fatini Abdul Ghani, Radiah
author_facet	Jamil, Elyna Fatini Abdul Ghani, Radiah
author_sort	Jamil, Elyna Fatini
title	The effects of Ficus auriculata (fig) on cell cycle profile and apoptosis activity of Human lung adenocarcinoma cells, A549
title_short	The effects of Ficus auriculata (fig) on cell cycle profile and apoptosis activity of Human lung adenocarcinoma cells, A549
title_full	The effects of Ficus auriculata (fig) on cell cycle profile and apoptosis activity of Human lung adenocarcinoma cells, A549
title_fullStr	The effects of Ficus auriculata (fig) on cell cycle profile and apoptosis activity of Human lung adenocarcinoma cells, A549
title_full_unstemmed	The effects of Ficus auriculata (fig) on cell cycle profile and apoptosis activity of Human lung adenocarcinoma cells, A549
title_sort	effects of ficus auriculata (fig) on cell cycle profile and apoptosis activity of human lung adenocarcinoma cells, a549
publishDate	2016
url	http://irep.iium.edu.my/53656/ http://irep.iium.edu.my/53656/ http://irep.iium.edu.my/53656/1/53656_The%20effects%20of%20Ficus%20auriculata.pdf
first_indexed	2023-09-18T21:15:53Z
last_indexed	2023-09-18T21:15:53Z
_version_	1777411559050444800

The effects of Ficus auriculata (fig) on cell cycle profile and apoptosis activity of Human lung adenocarcinoma cells, A549

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