Reliability of graphite furnace atomic absorption spectrometry as alternative method for trace analysis of arsenic in natural medicinal products
Purpose:To evaluate the comparative efficiency of graphite furnace atomic absorption spectrometry (GFAAS) and hydride generation atomic absorption spectrometry (HGAAS) for trace analysis of arsenic (As) in natural herbal products (NHPs). Method:Arsenic analysis in natural herbal p...
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iium-536672017-04-12T07:45:07Z http://irep.iium.edu.my/53667/ Reliability of graphite furnace atomic absorption spectrometry as alternative method for trace analysis of arsenic in natural medicinal products Khalid, Reem Saadi Abul Bashar Mohammed, Helaluddin Alaama, Mohamed Kasmuri, Abdul Razak Abbas, Syed Atif QD Chemistry RS Pharmacy and materia medica Purpose:To evaluate the comparative efficiency of graphite furnace atomic absorption spectrometry (GFAAS) and hydride generation atomic absorption spectrometry (HGAAS) for trace analysis of arsenic (As) in natural herbal products (NHPs). Method:Arsenic analysis in natural herbal products and standard reference material was conducted using atomic absorption spectrometry (AAS), namely, hydride generation AAS (HGAAS) and graphite furnace (GFAAS).The samples were digested with HNO 3 –H 2 O 2 in a ratio of 4:1 using microwave-assisted acid digestion. The methods were validated with the aid of the standard reference material 1515 Apple Leaves (SRM) from NIST Results: Mean recovery of three different samples of NHPs, using HGAAS and GFAAS, ranged from 89.3 - 91.4 %, and 91.7 - 93.0 %, respectively. The difference between the two methods was insignificant. A (P= 0.5), B (P=0.4) and C (P=0.88) Relative standard deviation (RSD) RSD, i.e., precision was 2.5 - 6.5 % and 2.3 - 6.7 % using HGAAS and GFAAS techniques,respectively. Recovery of arsenic in SRM was 98 and 102 % by GFAAS and HGAAS, respectively. Conclusion: GFAAS demonstrates acceptable levels of precision and accuracy. Both techniques possess comparable accuracy and repeatability. Thus, the two methods are recommended as an alternative approach for trace analysis of arsenic in natural herbal products. Pharmacotherapy Group,University of Benin 2016-09 Article PeerReviewed application/pdf en http://irep.iium.edu.my/53667/1/2016_15_9_22-2.pdf application/pdf en http://irep.iium.edu.my/53667/7/53667-Reliability%20of%20graphite%20furnace%20atomic%20absorption%20spectrometry%20as%20alternative%20method%20for%20trace%20analysis%20of%20arsenic%20in%20natural%20medicinal%20products_SCOPUS.pdf application/pdf en http://irep.iium.edu.my/53667/13/50902_Reliability%20analysis%20of%20multiphase%20flow%20measurements%20in%20different%20oil%20fields_WOS.pdf Khalid, Reem Saadi and Abul Bashar Mohammed, Helaluddin and Alaama, Mohamed and Kasmuri, Abdul Razak and Abbas, Syed Atif (2016) Reliability of graphite furnace atomic absorption spectrometry as alternative method for trace analysis of arsenic in natural medicinal products. Tropical Journal of Pharmaceutical Research, 15 (9). pp. 1967-1972. ISSN 1596-5996 E-ISSN 1596-9827 http://www.tjpr.org/admin/12389900798187/2016_15_9_22.pdf 10.4314/tjpr.v15i9.22 |
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| institution |
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QD Chemistry RS Pharmacy and materia medica |
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QD Chemistry RS Pharmacy and materia medica Khalid, Reem Saadi Abul Bashar Mohammed, Helaluddin Alaama, Mohamed Kasmuri, Abdul Razak Abbas, Syed Atif Reliability of graphite furnace atomic absorption spectrometry as alternative method for trace analysis of arsenic in natural medicinal products |
| description |
Purpose:To evaluate the comparative efficiency of graphite furnace atomic absorption spectrometry
(GFAAS) and hydride generation atomic absorption spectrometry (HGAAS) for trace analysis of arsenic
(As) in natural herbal products (NHPs).
Method:Arsenic analysis in natural herbal products and standard reference material was conducted
using atomic absorption spectrometry (AAS), namely, hydride generation AAS (HGAAS) and graphite furnace (GFAAS).The samples were digested with HNO 3 –H 2 O 2 in a ratio of 4:1 using microwave-assisted acid digestion. The methods were validated with the aid of the standard reference material 1515 Apple Leaves (SRM) from NIST
Results: Mean recovery of three different samples of NHPs, using HGAAS and GFAAS, ranged from 89.3 - 91.4 %, and 91.7 - 93.0 %, respectively. The difference between the two methods was insignificant. A (P= 0.5), B (P=0.4) and C (P=0.88) Relative standard deviation (RSD) RSD, i.e., precision was 2.5 - 6.5 % and 2.3 - 6.7 % using HGAAS and GFAAS techniques,respectively. Recovery of arsenic in SRM was 98 and 102 % by GFAAS and HGAAS, respectively.
Conclusion: GFAAS demonstrates acceptable levels of precision and accuracy. Both techniques possess comparable accuracy and repeatability. Thus, the two methods are recommended as an alternative approach for trace analysis of arsenic in natural herbal products. |
| format |
Article |
| author |
Khalid, Reem Saadi Abul Bashar Mohammed, Helaluddin Alaama, Mohamed Kasmuri, Abdul Razak Abbas, Syed Atif |
| author_facet |
Khalid, Reem Saadi Abul Bashar Mohammed, Helaluddin Alaama, Mohamed Kasmuri, Abdul Razak Abbas, Syed Atif |
| author_sort |
Khalid, Reem Saadi |
| title |
Reliability of graphite furnace atomic absorption
spectrometry as alternative method for trace analysis of
arsenic in natural medicinal products |
| title_short |
Reliability of graphite furnace atomic absorption
spectrometry as alternative method for trace analysis of
arsenic in natural medicinal products |
| title_full |
Reliability of graphite furnace atomic absorption
spectrometry as alternative method for trace analysis of
arsenic in natural medicinal products |
| title_fullStr |
Reliability of graphite furnace atomic absorption
spectrometry as alternative method for trace analysis of
arsenic in natural medicinal products |
| title_full_unstemmed |
Reliability of graphite furnace atomic absorption
spectrometry as alternative method for trace analysis of
arsenic in natural medicinal products |
| title_sort |
reliability of graphite furnace atomic absorption
spectrometry as alternative method for trace analysis of
arsenic in natural medicinal products |
| publisher |
Pharmacotherapy Group,University of Benin |
| publishDate |
2016 |
| url |
http://irep.iium.edu.my/53667/ http://irep.iium.edu.my/53667/ http://irep.iium.edu.my/53667/ http://irep.iium.edu.my/53667/1/2016_15_9_22-2.pdf http://irep.iium.edu.my/53667/7/53667-Reliability%20of%20graphite%20furnace%20atomic%20absorption%20spectrometry%20as%20alternative%20method%20for%20trace%20analysis%20of%20arsenic%20in%20natural%20medicinal%20products_SCOPUS.pdf http://irep.iium.edu.my/53667/13/50902_Reliability%20analysis%20of%20multiphase%20flow%20measurements%20in%20different%20oil%20fields_WOS.pdf |
| first_indexed |
2023-09-18T21:15:55Z |
| last_indexed |
2023-09-18T21:15:55Z |
| _version_ |
1777411560618065920 |