Placental morphology of pregnant Iraqi women with rheumatic heart disease

Background: Placental morphology and cellular arrangement can be altered in maternal diseases. Rheumatic heart disease (RHD) is a chronic heart condition that can lead to death in pregnant women. The aim of this study is to determine the histological changes of the placenta in pregnant women suffe...

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Main Authors:	Al-Assaf, Anwar IS, Al-Rubai, Ragwa HI, Al-Ani, Imad Matloub Dally, Al-Ubeidie, Salim R, Al-Kaisy, Kawkab SN, Faisal, Ghasak Ghazi
Format:	Article
Language:	English English
Published:	University Indonesia 2016
Subjects:	RB Pathology
Online Access:	http://irep.iium.edu.my/53720/ http://irep.iium.edu.my/53720/ http://irep.iium.edu.my/53720/ http://irep.iium.edu.my/53720/1/Placental%20Morphology%20of%20Pregnant%20Iraqi%20Women%20with%20Rheumatic%20Heart%20Disease.pdf http://irep.iium.edu.my/53720/7/53720-Placental%20morphology%20of%20pregnant%20Iraqi%20women%20with%20rheumatic%20heart%20disease_WOS.pdf

id	iium-53720
recordtype	eprints
spelling	iium-537202017-10-03T08:29:29Z http://irep.iium.edu.my/53720/ Placental morphology of pregnant Iraqi women with rheumatic heart disease Al-Assaf, Anwar IS Al-Rubai, Ragwa HI Al-Ani, Imad Matloub Dally Al-Ubeidie, Salim R Al-Kaisy, Kawkab SN Faisal, Ghasak Ghazi RB Pathology Background: Placental morphology and cellular arrangement can be altered in maternal diseases. Rheumatic heart disease (RHD) is a chronic heart condition that can lead to death in pregnant women. The aim of this study is to determine the histological changes of the placenta in pregnant women suffering from RHD. Methods: Placentae were collected from 10 healthy pregnant women, and 31 pregnant women with heart conditions (26 with RHD and 5 with NRHD) who had been admitted to the Baghdad Teaching Hospital. Placental tissues were fixed in10% formal-saline and were processed for light microscopy. Measurements including the placental weight and diameter of the chorionic villi capillaries were recorded. Results: The results indicate that there are many histological changes in pregnant women with RHD such as hyalinisation, fibrosis of the chorionic villi, proliferation of trophoblastic cells, and thickening of its membrane. Additionally, expectant mothers with RHD experience a reduction in capillary diameter and thickening of the capillary walls, and decreased size and weight of their placenta when compared with the control. Conclusions: Heart diseases, especially RHD, are associated with developmental damage of the placenta in pregnant women by injuring the endothelial cells of the placentas capillaries. University Indonesia 2016-12 Article PeerReviewed application/pdf en http://irep.iium.edu.my/53720/1/Placental%20Morphology%20of%20Pregnant%20Iraqi%20Women%20with%20Rheumatic%20Heart%20Disease.pdf application/pdf en http://irep.iium.edu.my/53720/7/53720-Placental%20morphology%20of%20pregnant%20Iraqi%20women%20with%20rheumatic%20heart%20disease_WOS.pdf Al-Assaf, Anwar IS and Al-Rubai, Ragwa HI and Al-Ani, Imad Matloub Dally and Al-Ubeidie, Salim R and Al-Kaisy, Kawkab SN and Faisal, Ghasak Ghazi (2016) Placental morphology of pregnant Iraqi women with rheumatic heart disease. Makara Journal of health research, 20 (3). pp. 89-93. ISSN 2356-3664 E-ISSN 2356-3656 http://journal.ui.ac.id/health 10.7454/msk.v20i3.6205
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	RB Pathology
spellingShingle	RB Pathology Al-Assaf, Anwar IS Al-Rubai, Ragwa HI Al-Ani, Imad Matloub Dally Al-Ubeidie, Salim R Al-Kaisy, Kawkab SN Faisal, Ghasak Ghazi Placental morphology of pregnant Iraqi women with rheumatic heart disease
description	Background: Placental morphology and cellular arrangement can be altered in maternal diseases. Rheumatic heart disease (RHD) is a chronic heart condition that can lead to death in pregnant women. The aim of this study is to determine the histological changes of the placenta in pregnant women suffering from RHD. Methods: Placentae were collected from 10 healthy pregnant women, and 31 pregnant women with heart conditions (26 with RHD and 5 with NRHD) who had been admitted to the Baghdad Teaching Hospital. Placental tissues were fixed in10% formal-saline and were processed for light microscopy. Measurements including the placental weight and diameter of the chorionic villi capillaries were recorded. Results: The results indicate that there are many histological changes in pregnant women with RHD such as hyalinisation, fibrosis of the chorionic villi, proliferation of trophoblastic cells, and thickening of its membrane. Additionally, expectant mothers with RHD experience a reduction in capillary diameter and thickening of the capillary walls, and decreased size and weight of their placenta when compared with the control. Conclusions: Heart diseases, especially RHD, are associated with developmental damage of the placenta in pregnant women by injuring the endothelial cells of the placentas capillaries.
format	Article
author	Al-Assaf, Anwar IS Al-Rubai, Ragwa HI Al-Ani, Imad Matloub Dally Al-Ubeidie, Salim R Al-Kaisy, Kawkab SN Faisal, Ghasak Ghazi
author_facet	Al-Assaf, Anwar IS Al-Rubai, Ragwa HI Al-Ani, Imad Matloub Dally Al-Ubeidie, Salim R Al-Kaisy, Kawkab SN Faisal, Ghasak Ghazi
author_sort	Al-Assaf, Anwar IS
title	Placental morphology of pregnant Iraqi women with rheumatic heart disease
title_short	Placental morphology of pregnant Iraqi women with rheumatic heart disease
title_full	Placental morphology of pregnant Iraqi women with rheumatic heart disease
title_fullStr	Placental morphology of pregnant Iraqi women with rheumatic heart disease
title_full_unstemmed	Placental morphology of pregnant Iraqi women with rheumatic heart disease
title_sort	placental morphology of pregnant iraqi women with rheumatic heart disease
publisher	University Indonesia
publishDate	2016
url	http://irep.iium.edu.my/53720/ http://irep.iium.edu.my/53720/ http://irep.iium.edu.my/53720/ http://irep.iium.edu.my/53720/1/Placental%20Morphology%20of%20Pregnant%20Iraqi%20Women%20with%20Rheumatic%20Heart%20Disease.pdf http://irep.iium.edu.my/53720/7/53720-Placental%20morphology%20of%20pregnant%20Iraqi%20women%20with%20rheumatic%20heart%20disease_WOS.pdf
first_indexed	2023-09-18T21:15:58Z
last_indexed	2023-09-18T21:15:58Z
_version_	1777411564129746944

Placental morphology of pregnant Iraqi women with rheumatic heart disease

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