Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients

Objective: To prove probable relations between serum E3 SUMO-protein ligase NSE2 (NSMCE2) concentration, peroxynitrite related to oxidative stress in nephrolithiasis patients. Methods: A total of 60 patients with nephrolithiasis and 50 healthy volunteers were involved in this study. Colorimetric...

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Main Authors:	Mehde, Atheer Awad, Yusof, Faridah, Mehdi, Wesen Adel, Ahmed Raus, Raha, Othman Farhan, Layla, Zainulabdeen, Jwan Abdulmohsin, Zainal Abidin, Zaima Azira, Ghazali, Hamid, Abd Rahman, Azlina
Format:	Article
Language:	English English
Published:	Elsevier BV 2016
Subjects:	R Medicine (General)
Online Access:	http://irep.iium.edu.my/54726/ http://irep.iium.edu.my/54726/ http://irep.iium.edu.my/54726/ http://irep.iium.edu.my/54726/13/54726_Serum%20E3%20SUMO-protein.pdf http://irep.iium.edu.my/54726/14/54726_Serum%20E3%20SUMO-protein_SCOPUS.pdf

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spelling	iium-547262017-02-21T07:51:55Z http://irep.iium.edu.my/54726/ Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients Mehde, Atheer Awad Yusof, Faridah Mehdi, Wesen Adel Ahmed Raus, Raha Othman Farhan, Layla Zainulabdeen, Jwan Abdulmohsin Zainal Abidin, Zaima Azira Ghazali, Hamid Abd Rahman, Azlina R Medicine (General) Objective: To prove probable relations between serum E3 SUMO-protein ligase NSE2 (NSMCE2) concentration, peroxynitrite related to oxidative stress in nephrolithiasis patients. Methods: A total of 60 patients with nephrolithiasis and 50 healthy volunteers were involved in this study. Colorimetric method was used to detect blood urea, creatinine, uric acid, protein, albumin, total antioxidant status, total oxidant status, peroxynitrite, nitric oxide and oxidative stress index. Glutathione, NSMCE2 and superoxide dismutase were measured by ELISA. Results: A significant increase in level of peroxynitrite, total oxidant status, NSMCE2 and oxidative stress index in patients was observed, while total antioxidant status and glutathione were significantly decreased. Conclusions: The study concluded that serum NSMCE2 significantly correlated with peroxynitrite and oxidative stress in patients with nephrolithiasis. Elsevier BV 2016-12-10 Article PeerReviewed application/pdf en http://irep.iium.edu.my/54726/13/54726_Serum%20E3%20SUMO-protein.pdf application/pdf en http://irep.iium.edu.my/54726/14/54726_Serum%20E3%20SUMO-protein_SCOPUS.pdf Mehde, Atheer Awad and Yusof, Faridah and Mehdi, Wesen Adel and Ahmed Raus, Raha and Othman Farhan, Layla and Zainulabdeen, Jwan Abdulmohsin and Zainal Abidin, Zaima Azira and Ghazali, Hamid and Abd Rahman, Azlina (2016) Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients. Asian Pacific Journal of Tropical Biomedicine, 7 (3). pp. 249-252. ISSN 2221-1691 http://ac.els-cdn.com/S2221169116302192/1-s2.0-S2221169116302192-main.pdf?_tid=f6f2e420-f808-11e6-9647-00000aab0f6c&acdnat=1487662986_f0120fdce9a679cc59600706bf5d349f 10.1016/j.apjtb.2016.12.008
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	R Medicine (General)
spellingShingle	R Medicine (General) Mehde, Atheer Awad Yusof, Faridah Mehdi, Wesen Adel Ahmed Raus, Raha Othman Farhan, Layla Zainulabdeen, Jwan Abdulmohsin Zainal Abidin, Zaima Azira Ghazali, Hamid Abd Rahman, Azlina Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients
description	Objective: To prove probable relations between serum E3 SUMO-protein ligase NSE2 (NSMCE2) concentration, peroxynitrite related to oxidative stress in nephrolithiasis patients. Methods: A total of 60 patients with nephrolithiasis and 50 healthy volunteers were involved in this study. Colorimetric method was used to detect blood urea, creatinine, uric acid, protein, albumin, total antioxidant status, total oxidant status, peroxynitrite, nitric oxide and oxidative stress index. Glutathione, NSMCE2 and superoxide dismutase were measured by ELISA. Results: A significant increase in level of peroxynitrite, total oxidant status, NSMCE2 and oxidative stress index in patients was observed, while total antioxidant status and glutathione were significantly decreased. Conclusions: The study concluded that serum NSMCE2 significantly correlated with peroxynitrite and oxidative stress in patients with nephrolithiasis.
format	Article
author	Mehde, Atheer Awad Yusof, Faridah Mehdi, Wesen Adel Ahmed Raus, Raha Othman Farhan, Layla Zainulabdeen, Jwan Abdulmohsin Zainal Abidin, Zaima Azira Ghazali, Hamid Abd Rahman, Azlina
author_facet	Mehde, Atheer Awad Yusof, Faridah Mehdi, Wesen Adel Ahmed Raus, Raha Othman Farhan, Layla Zainulabdeen, Jwan Abdulmohsin Zainal Abidin, Zaima Azira Ghazali, Hamid Abd Rahman, Azlina
author_sort	Mehde, Atheer Awad
title	Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients
title_short	Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients
title_full	Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients
title_fullStr	Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients
title_full_unstemmed	Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients
title_sort	serum e3 sumo-protein ligase nse2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients
publisher	Elsevier BV
publishDate	2016
url	http://irep.iium.edu.my/54726/ http://irep.iium.edu.my/54726/ http://irep.iium.edu.my/54726/ http://irep.iium.edu.my/54726/13/54726_Serum%20E3%20SUMO-protein.pdf http://irep.iium.edu.my/54726/14/54726_Serum%20E3%20SUMO-protein_SCOPUS.pdf
first_indexed	2023-09-18T21:17:23Z
last_indexed	2023-09-18T21:17:23Z
_version_	1777411653751537664

Serum E3 SUMO-protein ligase NSE2 level and peroxynitrite related to oxidative stress in nephrolithiasis patients

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