Ultrasound exposure during pregnancy affects rabbit foetal parathyroid hormone (PTH) level

The aim of this study was to investigate the changes in parathyroid hormone (PTH) level of rabbit foetal bodies exposed to ultrasound at different gestational stages. A total of 9 pregnant rabbits (Oryctolagus cuniculus) were insonated for 60 minutes at the middle of 1st, 2nd and 3rd gestational sta...

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Main Authors:	Md. Dom, Sulaiman, Abdul Razak, Hairil Rashmizal, Ahmad Zaiki, Farah Wahida, Saat, Nurul Hidayah, Abd Manan, Khairunnisa, Che Isa, Iza Nurzawani, Hashim, Ummi Farhana
Format:	Article
Language:	English
Published:	AME Publishing Company 2013
Subjects:	Q Science (General)
Online Access:	http://irep.iium.edu.my/55195/ http://irep.iium.edu.my/55195/ http://irep.iium.edu.my/55195/ http://irep.iium.edu.my/55195/1/SMD%2CFWAZ_2013.pdf

id	iium-55195
recordtype	eprints
spelling	iium-551952017-07-03T05:03:12Z http://irep.iium.edu.my/55195/ Ultrasound exposure during pregnancy affects rabbit foetal parathyroid hormone (PTH) level Md. Dom, Sulaiman Abdul Razak, Hairil Rashmizal Ahmad Zaiki, Farah Wahida Saat, Nurul Hidayah Abd Manan, Khairunnisa Che Isa, Iza Nurzawani Hashim, Ummi Farhana Q Science (General) The aim of this study was to investigate the changes in parathyroid hormone (PTH) level of rabbit foetal bodies exposed to ultrasound at different gestational stages. A total of 9 pregnant rabbits (Oryctolagus cuniculus) were insonated for 60 minutes at the middle of 1st, 2nd and 3rd gestational stages for group A (n=14 newborns), group B (n=7 newborns ) and group C (n=24 newborns) respectively. Seven pregnant rabbits with 41 newborns severed as negative control group. Blood samples were withdrawn from each newborn rabbits for Parathyroid Hormone-Intact (PTH-I) test. Results of the independent samples t-test implied statistically significant differences (P<0.05) between the control group and the 1st stage (P=0.001), the 2nd stage (P<0.001) and the 3rd stage group (P<0.001). This in-vivo study revealed diagnostic ultrasound heating has the potential of affecting foetal PTH level. This study observed significantly low PTH level for all the treated groups. A further study should be instituted to determine whether this finding in rabbit may also occur in human by means of clinical trials. AME Publishing Company 2013 Article PeerReviewed application/pdf en http://irep.iium.edu.my/55195/1/SMD%2CFWAZ_2013.pdf Md. Dom, Sulaiman and Abdul Razak, Hairil Rashmizal and Ahmad Zaiki, Farah Wahida and Saat, Nurul Hidayah and Abd Manan, Khairunnisa and Che Isa, Iza Nurzawani and Hashim, Ummi Farhana (2013) Ultrasound exposure during pregnancy affects rabbit foetal parathyroid hormone (PTH) level. Quantitative Imaging in Medicine and Surgery, 3 (1). pp. 49-53. ISSN 2223-4292 E-ISSN 2223-4306 http://qims.amegroups.com/article/view/1591/2247 10.3978/j.issn.2223-4292.2013.02.06
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	Q Science (General)
spellingShingle	Q Science (General) Md. Dom, Sulaiman Abdul Razak, Hairil Rashmizal Ahmad Zaiki, Farah Wahida Saat, Nurul Hidayah Abd Manan, Khairunnisa Che Isa, Iza Nurzawani Hashim, Ummi Farhana Ultrasound exposure during pregnancy affects rabbit foetal parathyroid hormone (PTH) level
description	The aim of this study was to investigate the changes in parathyroid hormone (PTH) level of rabbit foetal bodies exposed to ultrasound at different gestational stages. A total of 9 pregnant rabbits (Oryctolagus cuniculus) were insonated for 60 minutes at the middle of 1st, 2nd and 3rd gestational stages for group A (n=14 newborns), group B (n=7 newborns ) and group C (n=24 newborns) respectively. Seven pregnant rabbits with 41 newborns severed as negative control group. Blood samples were withdrawn from each newborn rabbits for Parathyroid Hormone-Intact (PTH-I) test. Results of the independent samples t-test implied statistically significant differences (P<0.05) between the control group and the 1st stage (P=0.001), the 2nd stage (P<0.001) and the 3rd stage group (P<0.001). This in-vivo study revealed diagnostic ultrasound heating has the potential of affecting foetal PTH level. This study observed significantly low PTH level for all the treated groups. A further study should be instituted to determine whether this finding in rabbit may also occur in human by means of clinical trials.
format	Article
author	Md. Dom, Sulaiman Abdul Razak, Hairil Rashmizal Ahmad Zaiki, Farah Wahida Saat, Nurul Hidayah Abd Manan, Khairunnisa Che Isa, Iza Nurzawani Hashim, Ummi Farhana
author_facet	Md. Dom, Sulaiman Abdul Razak, Hairil Rashmizal Ahmad Zaiki, Farah Wahida Saat, Nurul Hidayah Abd Manan, Khairunnisa Che Isa, Iza Nurzawani Hashim, Ummi Farhana
author_sort	Md. Dom, Sulaiman
title	Ultrasound exposure during pregnancy affects rabbit foetal parathyroid hormone (PTH) level
title_short	Ultrasound exposure during pregnancy affects rabbit foetal parathyroid hormone (PTH) level
title_full	Ultrasound exposure during pregnancy affects rabbit foetal parathyroid hormone (PTH) level
title_fullStr	Ultrasound exposure during pregnancy affects rabbit foetal parathyroid hormone (PTH) level
title_full_unstemmed	Ultrasound exposure during pregnancy affects rabbit foetal parathyroid hormone (PTH) level
title_sort	ultrasound exposure during pregnancy affects rabbit foetal parathyroid hormone (pth) level
publisher	AME Publishing Company
publishDate	2013
url	http://irep.iium.edu.my/55195/ http://irep.iium.edu.my/55195/ http://irep.iium.edu.my/55195/ http://irep.iium.edu.my/55195/1/SMD%2CFWAZ_2013.pdf
first_indexed	2023-09-18T21:18:02Z
last_indexed	2023-09-18T21:18:02Z
_version_	1777411694355546112

Ultrasound exposure during pregnancy affects rabbit foetal parathyroid hormone (PTH) level

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