Synthesis and characterization of functionalized Se-MCM-41 a new drug carrier mesopore composite

Various nanocomposite materials play a number of important roles in modern science and technology including pharmaceutical science. Among these materials, mesoporous materials cover a large number of applications in drug delivery system. The quantitative incorporation and high dispersion of selen...

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Main Authors: Rahman, Md. Mokhlesur, Md Aris, Mohd Aznan, Yusof, Alias Mohd, Ansaryr, H., Siddiqui, Mohammad Jamshed Ahmad, Yusan, S.
Format: Article
Language:English
English
English
Published: Oriental Scientific Publishing Company 2017
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Online Access:http://irep.iium.edu.my/56753/
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http://irep.iium.edu.my/56753/
http://irep.iium.edu.my/56753/7/56753_Synthesis%20and%20characterization%20of%20functionalized%20Se-MCM-41_Scopus.pdf
http://irep.iium.edu.my/56753/13/56753_Synthesis%20and%20characterization%20of%20functionalized.pdf
http://irep.iium.edu.my/56753/14/56753_Synthesis%20and%20characterization%20of%20functionalized_WOS.pdf
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spelling iium-567532017-09-20T00:47:09Z http://irep.iium.edu.my/56753/ Synthesis and characterization of functionalized Se-MCM-41 a new drug carrier mesopore composite Rahman, Md. Mokhlesur Md Aris, Mohd Aznan Yusof, Alias Mohd Ansaryr, H. Siddiqui, Mohammad Jamshed Ahmad Yusan, S. QD Chemistry Various nanocomposite materials play a number of important roles in modern science and technology including pharmaceutical science. Among these materials, mesoporous materials cover a large number of applications in drug delivery system. The quantitative incorporation and high dispersion of selenium nanoparticles into MCM-41 have been made possible by the coordination between Se(IV) ion and aminopropyltriethoxysilane (APTES)-anchored MCM-41. The samples were characterized by X-ray powder diffraction, Fourier-transformed infrared spectroscopy (FTIR), scanning electron microscopy (SEM), nitrogen adsorption–desorption via multi-point Brunauer, Emmett and Teller (BET) analysis, Raman spectroscopy and UV-Vis diffusion reflection spectroscopy (UV-vis/DRS). The increase in cell parameter and the decrease in surface area observed by N2 adsorption-desorption technique were taken as evidence of selenium introduction inside the MCM-41 framework. The behaviour of drug release in these nanocomposites is probably due to hydrogen bonding interactions between drug and the hydroxyl group on the composite framework. Oriental Scientific Publishing Company 2017 Article PeerReviewed application/pdf en http://irep.iium.edu.my/56753/7/56753_Synthesis%20and%20characterization%20of%20functionalized%20Se-MCM-41_Scopus.pdf application/pdf en http://irep.iium.edu.my/56753/13/56753_Synthesis%20and%20characterization%20of%20functionalized.pdf application/pdf en http://irep.iium.edu.my/56753/14/56753_Synthesis%20and%20characterization%20of%20functionalized_WOS.pdf Rahman, Md. Mokhlesur and Md Aris, Mohd Aznan and Yusof, Alias Mohd and Ansaryr, H. and Siddiqui, Mohammad Jamshed Ahmad and Yusan, S. (2017) Synthesis and characterization of functionalized Se-MCM-41 a new drug carrier mesopore composite. Oriental Journal Of Chemistry, 33 (2). pp. 611-621. ISSN 0970-020X E-ISSN 2231-5039 http://www.orientjchem.org/vol33no2/synthesis-and-characterization-of-functionalized-se-mcm-41-a-new-drug-carrier-mesopore-composite/ 10.13005/ojc/330208
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
English
English
topic QD Chemistry
spellingShingle QD Chemistry
Rahman, Md. Mokhlesur
Md Aris, Mohd Aznan
Yusof, Alias Mohd
Ansaryr, H.
Siddiqui, Mohammad Jamshed Ahmad
Yusan, S.
Synthesis and characterization of functionalized Se-MCM-41 a new drug carrier mesopore composite
description Various nanocomposite materials play a number of important roles in modern science and technology including pharmaceutical science. Among these materials, mesoporous materials cover a large number of applications in drug delivery system. The quantitative incorporation and high dispersion of selenium nanoparticles into MCM-41 have been made possible by the coordination between Se(IV) ion and aminopropyltriethoxysilane (APTES)-anchored MCM-41. The samples were characterized by X-ray powder diffraction, Fourier-transformed infrared spectroscopy (FTIR), scanning electron microscopy (SEM), nitrogen adsorption–desorption via multi-point Brunauer, Emmett and Teller (BET) analysis, Raman spectroscopy and UV-Vis diffusion reflection spectroscopy (UV-vis/DRS). The increase in cell parameter and the decrease in surface area observed by N2 adsorption-desorption technique were taken as evidence of selenium introduction inside the MCM-41 framework. The behaviour of drug release in these nanocomposites is probably due to hydrogen bonding interactions between drug and the hydroxyl group on the composite framework.
format Article
author Rahman, Md. Mokhlesur
Md Aris, Mohd Aznan
Yusof, Alias Mohd
Ansaryr, H.
Siddiqui, Mohammad Jamshed Ahmad
Yusan, S.
author_facet Rahman, Md. Mokhlesur
Md Aris, Mohd Aznan
Yusof, Alias Mohd
Ansaryr, H.
Siddiqui, Mohammad Jamshed Ahmad
Yusan, S.
author_sort Rahman, Md. Mokhlesur
title Synthesis and characterization of functionalized Se-MCM-41 a new drug carrier mesopore composite
title_short Synthesis and characterization of functionalized Se-MCM-41 a new drug carrier mesopore composite
title_full Synthesis and characterization of functionalized Se-MCM-41 a new drug carrier mesopore composite
title_fullStr Synthesis and characterization of functionalized Se-MCM-41 a new drug carrier mesopore composite
title_full_unstemmed Synthesis and characterization of functionalized Se-MCM-41 a new drug carrier mesopore composite
title_sort synthesis and characterization of functionalized se-mcm-41 a new drug carrier mesopore composite
publisher Oriental Scientific Publishing Company
publishDate 2017
url http://irep.iium.edu.my/56753/
http://irep.iium.edu.my/56753/
http://irep.iium.edu.my/56753/
http://irep.iium.edu.my/56753/7/56753_Synthesis%20and%20characterization%20of%20functionalized%20Se-MCM-41_Scopus.pdf
http://irep.iium.edu.my/56753/13/56753_Synthesis%20and%20characterization%20of%20functionalized.pdf
http://irep.iium.edu.my/56753/14/56753_Synthesis%20and%20characterization%20of%20functionalized_WOS.pdf
first_indexed 2023-09-18T21:20:08Z
last_indexed 2023-09-18T21:20:08Z
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