Synthesis and characterization of functionalized Se-MCM-41 a new drug carrier mesopore composite
Various nanocomposite materials play a number of important roles in modern science and technology including pharmaceutical science. Among these materials, mesoporous materials cover a large number of applications in drug delivery system. The quantitative incorporation and high dispersion of selen...
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Oriental Scientific Publishing Company
2017
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iium-567532017-09-20T00:47:09Z http://irep.iium.edu.my/56753/ Synthesis and characterization of functionalized Se-MCM-41 a new drug carrier mesopore composite Rahman, Md. Mokhlesur Md Aris, Mohd Aznan Yusof, Alias Mohd Ansaryr, H. Siddiqui, Mohammad Jamshed Ahmad Yusan, S. QD Chemistry Various nanocomposite materials play a number of important roles in modern science and technology including pharmaceutical science. Among these materials, mesoporous materials cover a large number of applications in drug delivery system. The quantitative incorporation and high dispersion of selenium nanoparticles into MCM-41 have been made possible by the coordination between Se(IV) ion and aminopropyltriethoxysilane (APTES)-anchored MCM-41. The samples were characterized by X-ray powder diffraction, Fourier-transformed infrared spectroscopy (FTIR), scanning electron microscopy (SEM), nitrogen adsorption–desorption via multi-point Brunauer, Emmett and Teller (BET) analysis, Raman spectroscopy and UV-Vis diffusion reflection spectroscopy (UV-vis/DRS). The increase in cell parameter and the decrease in surface area observed by N2 adsorption-desorption technique were taken as evidence of selenium introduction inside the MCM-41 framework. The behaviour of drug release in these nanocomposites is probably due to hydrogen bonding interactions between drug and the hydroxyl group on the composite framework. Oriental Scientific Publishing Company 2017 Article PeerReviewed application/pdf en http://irep.iium.edu.my/56753/7/56753_Synthesis%20and%20characterization%20of%20functionalized%20Se-MCM-41_Scopus.pdf application/pdf en http://irep.iium.edu.my/56753/13/56753_Synthesis%20and%20characterization%20of%20functionalized.pdf application/pdf en http://irep.iium.edu.my/56753/14/56753_Synthesis%20and%20characterization%20of%20functionalized_WOS.pdf Rahman, Md. Mokhlesur and Md Aris, Mohd Aznan and Yusof, Alias Mohd and Ansaryr, H. and Siddiqui, Mohammad Jamshed Ahmad and Yusan, S. (2017) Synthesis and characterization of functionalized Se-MCM-41 a new drug carrier mesopore composite. Oriental Journal Of Chemistry, 33 (2). pp. 611-621. ISSN 0970-020X E-ISSN 2231-5039 http://www.orientjchem.org/vol33no2/synthesis-and-characterization-of-functionalized-se-mcm-41-a-new-drug-carrier-mesopore-composite/ 10.13005/ojc/330208 |
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QD Chemistry Rahman, Md. Mokhlesur Md Aris, Mohd Aznan Yusof, Alias Mohd Ansaryr, H. Siddiqui, Mohammad Jamshed Ahmad Yusan, S. Synthesis and characterization of functionalized Se-MCM-41 a new drug carrier mesopore composite |
description |
Various nanocomposite materials play a number of important roles in modern science and
technology including pharmaceutical science. Among these materials, mesoporous materials cover
a large number of applications in drug delivery system. The quantitative incorporation and high
dispersion of selenium nanoparticles into MCM-41 have been made possible by the coordination
between Se(IV) ion and aminopropyltriethoxysilane (APTES)-anchored MCM-41. The samples
were characterized by X-ray powder diffraction, Fourier-transformed infrared spectroscopy (FTIR),
scanning electron microscopy (SEM), nitrogen adsorption–desorption via multi-point Brunauer, Emmett and Teller (BET) analysis, Raman spectroscopy and UV-Vis diffusion reflection spectroscopy (UV-vis/DRS). The increase in cell parameter and the decrease in surface area observed by N2 adsorption-desorption technique were taken as evidence of selenium introduction inside the MCM-41 framework. The behaviour of drug release in these nanocomposites is probably due to hydrogen bonding interactions between drug and the hydroxyl group on the composite framework. |
format |
Article |
author |
Rahman, Md. Mokhlesur Md Aris, Mohd Aznan Yusof, Alias Mohd Ansaryr, H. Siddiqui, Mohammad Jamshed Ahmad Yusan, S. |
author_facet |
Rahman, Md. Mokhlesur Md Aris, Mohd Aznan Yusof, Alias Mohd Ansaryr, H. Siddiqui, Mohammad Jamshed Ahmad Yusan, S. |
author_sort |
Rahman, Md. Mokhlesur |
title |
Synthesis and characterization of functionalized Se-MCM-41
a new drug carrier mesopore composite |
title_short |
Synthesis and characterization of functionalized Se-MCM-41
a new drug carrier mesopore composite |
title_full |
Synthesis and characterization of functionalized Se-MCM-41
a new drug carrier mesopore composite |
title_fullStr |
Synthesis and characterization of functionalized Se-MCM-41
a new drug carrier mesopore composite |
title_full_unstemmed |
Synthesis and characterization of functionalized Se-MCM-41
a new drug carrier mesopore composite |
title_sort |
synthesis and characterization of functionalized se-mcm-41
a new drug carrier mesopore composite |
publisher |
Oriental Scientific Publishing Company |
publishDate |
2017 |
url |
http://irep.iium.edu.my/56753/ http://irep.iium.edu.my/56753/ http://irep.iium.edu.my/56753/ http://irep.iium.edu.my/56753/7/56753_Synthesis%20and%20characterization%20of%20functionalized%20Se-MCM-41_Scopus.pdf http://irep.iium.edu.my/56753/13/56753_Synthesis%20and%20characterization%20of%20functionalized.pdf http://irep.iium.edu.my/56753/14/56753_Synthesis%20and%20characterization%20of%20functionalized_WOS.pdf |
first_indexed |
2023-09-18T21:20:08Z |
last_indexed |
2023-09-18T21:20:08Z |
_version_ |
1777411826523308032 |