Nanohydroxyapatite-coated hydroxyethyl cellulose/poly (vinyl) alcohol electrospun scaffolds and their cellular response

The present study focused on the preparation of nanohydroxyapatite (nHA)-coated hydroxyethyl cellulose/polyvinyl alcohol (HEC/PVA) nanofibrous scaffolds for bone tissue engineering application. The electrospun HEC/PVA scaffolds were mineralized via alternate soaking process. FESEM revealed that the...

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Main Authors:	Chahal, Sugandha, Jahir Hussain, Fathima Shahitha, Mohd Yusoff, Mashitah, Abdull Rasad, Mohammad Syaiful Bahari, Kumar, Anuj
Format:	Article
Language:	English English English
Published:	Taylor & Francis Online 2017
Subjects:	Q Science (General)
Online Access:	http://irep.iium.edu.my/57199/ http://irep.iium.edu.my/57199/ http://irep.iium.edu.my/57199/2/57199_Nanohydroxyapatite-coated_SCOPUS.pdf http://irep.iium.edu.my/57199/3/57199_Nanohydroxyapatite-coated_WOS.pdf http://irep.iium.edu.my/57199/19/57199_Nanohydroxyapatite-coated%20hydroxyethyl.pdf

id	iium-57199
recordtype	eprints
spelling	iium-571992017-08-02T01:36:41Z http://irep.iium.edu.my/57199/ Nanohydroxyapatite-coated hydroxyethyl cellulose/poly (vinyl) alcohol electrospun scaffolds and their cellular response Chahal, Sugandha Jahir Hussain, Fathima Shahitha Mohd Yusoff, Mashitah Abdull Rasad, Mohammad Syaiful Bahari Kumar, Anuj Q Science (General) The present study focused on the preparation of nanohydroxyapatite (nHA)-coated hydroxyethyl cellulose/polyvinyl alcohol (HEC/PVA) nanofibrous scaffolds for bone tissue engineering application. The electrospun HEC/PVA scaffolds were mineralized via alternate soaking process. FESEM revealed that the nHA was formed uniformly over the nanofibers. The nHA mineralization enhanced the tensile strength and reduced the elongation at breakage of scaffolds. The wettability of the nanofibrous scaffolds was significantly improved. The in vitro biocompatibility of scaffolds was evaluated with human osteosarcoma cells. nHA-coated scaffolds had a favorable effect on the proliferation and differentiation of osteosarcoma cell and could be a potential candidate for bone regeneration. Taylor & Francis Online 2017 Article PeerReviewed application/pdf en http://irep.iium.edu.my/57199/2/57199_Nanohydroxyapatite-coated_SCOPUS.pdf application/pdf en http://irep.iium.edu.my/57199/3/57199_Nanohydroxyapatite-coated_WOS.pdf application/pdf en http://irep.iium.edu.my/57199/19/57199_Nanohydroxyapatite-coated%20hydroxyethyl.pdf Chahal, Sugandha and Jahir Hussain, Fathima Shahitha and Mohd Yusoff, Mashitah and Abdull Rasad, Mohammad Syaiful Bahari and Kumar, Anuj (2017) Nanohydroxyapatite-coated hydroxyethyl cellulose/poly (vinyl) alcohol electrospun scaffolds and their cellular response. International Journal of Polymeric Materials and Polymeric Biomaterials, 66 (3). pp. 115-122. ISSN 0091-4037 E-ISSN 1563-535X http://www.tandfonline.com/doi/abs/10.1080/00914037.2016.1190926?journalCode=gpom20
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English English
topic	Q Science (General)
spellingShingle	Q Science (General) Chahal, Sugandha Jahir Hussain, Fathima Shahitha Mohd Yusoff, Mashitah Abdull Rasad, Mohammad Syaiful Bahari Kumar, Anuj Nanohydroxyapatite-coated hydroxyethyl cellulose/poly (vinyl) alcohol electrospun scaffolds and their cellular response
description	The present study focused on the preparation of nanohydroxyapatite (nHA)-coated hydroxyethyl cellulose/polyvinyl alcohol (HEC/PVA) nanofibrous scaffolds for bone tissue engineering application. The electrospun HEC/PVA scaffolds were mineralized via alternate soaking process. FESEM revealed that the nHA was formed uniformly over the nanofibers. The nHA mineralization enhanced the tensile strength and reduced the elongation at breakage of scaffolds. The wettability of the nanofibrous scaffolds was significantly improved. The in vitro biocompatibility of scaffolds was evaluated with human osteosarcoma cells. nHA-coated scaffolds had a favorable effect on the proliferation and differentiation of osteosarcoma cell and could be a potential candidate for bone regeneration.
format	Article
author	Chahal, Sugandha Jahir Hussain, Fathima Shahitha Mohd Yusoff, Mashitah Abdull Rasad, Mohammad Syaiful Bahari Kumar, Anuj
author_facet	Chahal, Sugandha Jahir Hussain, Fathima Shahitha Mohd Yusoff, Mashitah Abdull Rasad, Mohammad Syaiful Bahari Kumar, Anuj
author_sort	Chahal, Sugandha
title	Nanohydroxyapatite-coated hydroxyethyl cellulose/poly (vinyl) alcohol electrospun scaffolds and their cellular response
title_short	Nanohydroxyapatite-coated hydroxyethyl cellulose/poly (vinyl) alcohol electrospun scaffolds and their cellular response
title_full	Nanohydroxyapatite-coated hydroxyethyl cellulose/poly (vinyl) alcohol electrospun scaffolds and their cellular response
title_fullStr	Nanohydroxyapatite-coated hydroxyethyl cellulose/poly (vinyl) alcohol electrospun scaffolds and their cellular response
title_full_unstemmed	Nanohydroxyapatite-coated hydroxyethyl cellulose/poly (vinyl) alcohol electrospun scaffolds and their cellular response
title_sort	nanohydroxyapatite-coated hydroxyethyl cellulose/poly (vinyl) alcohol electrospun scaffolds and their cellular response
publisher	Taylor & Francis Online
publishDate	2017
url	http://irep.iium.edu.my/57199/ http://irep.iium.edu.my/57199/ http://irep.iium.edu.my/57199/2/57199_Nanohydroxyapatite-coated_SCOPUS.pdf http://irep.iium.edu.my/57199/3/57199_Nanohydroxyapatite-coated_WOS.pdf http://irep.iium.edu.my/57199/19/57199_Nanohydroxyapatite-coated%20hydroxyethyl.pdf
first_indexed	2023-09-18T21:20:48Z
last_indexed	2023-09-18T21:20:48Z
_version_	1777411868654043136

Nanohydroxyapatite-coated hydroxyethyl cellulose/poly (vinyl) alcohol electrospun scaffolds and their cellular response

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