Allergic cutaneous and visceral angioedema secondary to clozapine: A case report
This report stresses on the occurrence of a rare adverse reaction to clozapine, i.e. allergic cutaneous and visceral angioedema, in a patient with treatment resistant schizophrenia (TRS). We report the case of a schizophrenic patient who was resistant to treatment and developed an allergic reacti...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Medical Research & Innovation Secretariat, Universiti Kebangsaan Malaysia Medical Centre
2017
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/57579/ http://irep.iium.edu.my/57579/ http://irep.iium.edu.my/57579/1/ahmad%20nabil.pdf |
| Summary: | This report stresses on the occurrence of a rare adverse reaction to clozapine, i.e.
allergic cutaneous and visceral angioedema, in a patient with treatment resistant
schizophrenia (TRS). We report the case of a schizophrenic patient who was
resistant to treatment and developed an allergic reaction involving her skin and
gastro-intestinal system upon the commencement of clozapine. She was then
treated with a combination pharmacotherapy which left some residual symptoms.
The manifestation of allergic reactions to clozapine and its management strategies
are discussed in the paper. There is a pressing need to develop a new psychotropic
which is on par with clozapine
Laporan ini menerangkan kejadian tindak balas ubat clozapine yang jarang berlaku,
iaitu alahan kutaneus dan angioedema visera, pada seorang pesakit skizofrenia
yang tidak menunjukkan kesan terhadap rawatan ubat-ubatan yang biasa. Kami
melaporkan seorang pesakit skizofrenia rintang-rawatan yang mengalami masalah
alahan pada kulit dan sistem gastro-usus sejurus beliau menerima rawatan ubat
clozapine. Beliau kemudiannya dirawat dengan kombinasi beberapa ubat-ubatan,
namun masih mengalami gejala-gejala residual. Manifestasi alahan kepada ubat
clozapine and strategi perawatan dibincangkan di dalam laporan kes ini. Terdapat
keperluan yang mendesak bagi penghasilan ubat psikotropik yang setanding
clozapine untuk merawat pesakit, memandangkan masalah alahan ubat seperti
laporan kes ini |
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