Allergic cutaneous and visceral angioedema secondary to clozapine: A case report

This report stresses on the occurrence of a rare adverse reaction to clozapine, i.e. allergic cutaneous and visceral angioedema, in a patient with treatment resistant schizophrenia (TRS). We report the case of a schizophrenic patient who was resistant to treatment and developed an allergic reacti...

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Main Authors:	Chia, LC, Md Rosli, Ahmad Nabil, M, Marhani, A, Muna Hamiza
Format:	Article
Language:	English
Published:	Medical Research & Innovation Secretariat, Universiti Kebangsaan Malaysia Medical Centre 2017
Subjects:	RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
Online Access:	http://irep.iium.edu.my/57579/ http://irep.iium.edu.my/57579/ http://irep.iium.edu.my/57579/1/ahmad%20nabil.pdf

id	iium-57579
recordtype	eprints
spelling	iium-575792018-03-09T07:09:39Z http://irep.iium.edu.my/57579/ Allergic cutaneous and visceral angioedema secondary to clozapine: A case report Chia, LC Md Rosli, Ahmad Nabil M, Marhani A, Muna Hamiza RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry This report stresses on the occurrence of a rare adverse reaction to clozapine, i.e. allergic cutaneous and visceral angioedema, in a patient with treatment resistant schizophrenia (TRS). We report the case of a schizophrenic patient who was resistant to treatment and developed an allergic reaction involving her skin and gastro-intestinal system upon the commencement of clozapine. She was then treated with a combination pharmacotherapy which left some residual symptoms. The manifestation of allergic reactions to clozapine and its management strategies are discussed in the paper. There is a pressing need to develop a new psychotropic which is on par with clozapine Laporan ini menerangkan kejadian tindak balas ubat clozapine yang jarang berlaku, iaitu alahan kutaneus dan angioedema visera, pada seorang pesakit skizofrenia yang tidak menunjukkan kesan terhadap rawatan ubat-ubatan yang biasa. Kami melaporkan seorang pesakit skizofrenia rintang-rawatan yang mengalami masalah alahan pada kulit dan sistem gastro-usus sejurus beliau menerima rawatan ubat clozapine. Beliau kemudiannya dirawat dengan kombinasi beberapa ubat-ubatan, namun masih mengalami gejala-gejala residual. Manifestasi alahan kepada ubat clozapine and strategi perawatan dibincangkan di dalam laporan kes ini. Terdapat keperluan yang mendesak bagi penghasilan ubat psikotropik yang setanding clozapine untuk merawat pesakit, memandangkan masalah alahan ubat seperti laporan kes ini Medical Research & Innovation Secretariat, Universiti Kebangsaan Malaysia Medical Centre 2017 Article PeerReviewed application/pdf en http://irep.iium.edu.my/57579/1/ahmad%20nabil.pdf Chia, LC and Md Rosli, Ahmad Nabil and M, Marhani and A, Muna Hamiza (2017) Allergic cutaneous and visceral angioedema secondary to clozapine: A case report. Medicine and Health, 12 (1). pp. 122-126. E-ISSN 2289-5728 http://www.medicineandhealthukm.com/sites/medicineandhealthukm.com/files/article/2017/17_chia_et_al_pdf_70617.pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry
spellingShingle	RC0321 Neuroscience. Biological psychiatry. Neuropsychiatry Chia, LC Md Rosli, Ahmad Nabil M, Marhani A, Muna Hamiza Allergic cutaneous and visceral angioedema secondary to clozapine: A case report
description	This report stresses on the occurrence of a rare adverse reaction to clozapine, i.e. allergic cutaneous and visceral angioedema, in a patient with treatment resistant schizophrenia (TRS). We report the case of a schizophrenic patient who was resistant to treatment and developed an allergic reaction involving her skin and gastro-intestinal system upon the commencement of clozapine. She was then treated with a combination pharmacotherapy which left some residual symptoms. The manifestation of allergic reactions to clozapine and its management strategies are discussed in the paper. There is a pressing need to develop a new psychotropic which is on par with clozapine Laporan ini menerangkan kejadian tindak balas ubat clozapine yang jarang berlaku, iaitu alahan kutaneus dan angioedema visera, pada seorang pesakit skizofrenia yang tidak menunjukkan kesan terhadap rawatan ubat-ubatan yang biasa. Kami melaporkan seorang pesakit skizofrenia rintang-rawatan yang mengalami masalah alahan pada kulit dan sistem gastro-usus sejurus beliau menerima rawatan ubat clozapine. Beliau kemudiannya dirawat dengan kombinasi beberapa ubat-ubatan, namun masih mengalami gejala-gejala residual. Manifestasi alahan kepada ubat clozapine and strategi perawatan dibincangkan di dalam laporan kes ini. Terdapat keperluan yang mendesak bagi penghasilan ubat psikotropik yang setanding clozapine untuk merawat pesakit, memandangkan masalah alahan ubat seperti laporan kes ini
format	Article
author	Chia, LC Md Rosli, Ahmad Nabil M, Marhani A, Muna Hamiza
author_facet	Chia, LC Md Rosli, Ahmad Nabil M, Marhani A, Muna Hamiza
author_sort	Chia, LC
title	Allergic cutaneous and visceral angioedema secondary to clozapine: A case report
title_short	Allergic cutaneous and visceral angioedema secondary to clozapine: A case report
title_full	Allergic cutaneous and visceral angioedema secondary to clozapine: A case report
title_fullStr	Allergic cutaneous and visceral angioedema secondary to clozapine: A case report
title_full_unstemmed	Allergic cutaneous and visceral angioedema secondary to clozapine: A case report
title_sort	allergic cutaneous and visceral angioedema secondary to clozapine: a case report
publisher	Medical Research & Innovation Secretariat, Universiti Kebangsaan Malaysia Medical Centre
publishDate	2017
url	http://irep.iium.edu.my/57579/ http://irep.iium.edu.my/57579/ http://irep.iium.edu.my/57579/1/ahmad%20nabil.pdf
first_indexed	2023-09-18T21:21:24Z
last_indexed	2023-09-18T21:21:24Z
_version_	1777411906108129280

Allergic cutaneous and visceral angioedema secondary to clozapine: A case report

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