Abdominal obesity and high-sensitivity C-reactive protein level among Malay obese adults in Kuantan, Malaysia
Introduction: Abdominal obesity and inflammation are two independent risk factors for cardiovascular disease. However, the inter-relationship between these two factors among Malay population is fragmented. The purpose of this study is to determine the association between waist circumference as a mea...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English English English |
| Published: |
Kulliyyah (Faculty) of Medicine, International Islamic University Malaysia
2018
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| Online Access: | http://irep.iium.edu.my/58135/ http://irep.iium.edu.my/58135/ http://irep.iium.edu.my/58135/19/58135%20Abdominal%20Obesity%20and%20High-sensitivity%20C-reactive.pdf http://irep.iium.edu.my/58135/13/58135_Abdominal%20Obesity%20and%20High-sensitivity%20C-reactive%20Protein%20Level_SCOPUS.pdf http://irep.iium.edu.my/58135/25/58135_Abdominal%20Obesity%20and%20High-sensitivity%20C-reactive%20Protein%20Level%20among%20Malay%20Obese%20Adults%20in%20Kuantan%2C%20Malaysia_WOS.pdf |
| Summary: | Introduction: Abdominal obesity and inflammation are two independent risk factors for cardiovascular disease. However, the inter-relationship between these two factors among Malay population is fragmented. The purpose of this study is to determine the association between waist circumference as a measure of abdominal obesity and high-sensitivity C-reactive protein as an indicator of inflammation status among Malay obese adults in Kuantan, Pahang.
Materials and Methods: Ninety-three apparently healthy obese adults (BMI between 27.5 and 39.9 kg/m2) aged between 20 to 62 years old were recruited in this study (68% men and 32% women). Circumference tape was used to measure the waist circumference and fasting venous blood was obtained to determine the high-sensitivity C-reactive protein level.
Results: On average, the waist circumference of obese men and women was 103 cm (SD = 8.7) and 94 cm (SD = 7.0), respectively. The median (IQR) of the hs-CRP level of the study participant was 3.80 mg/L (1.5, 10.1). The Kendall’s Tau correlation reveals that there is a significant positive linear correlation between waist circumference and hs-CRP level in obese men (r (30) = 0.355, p = 0.006) and women (r (63) = 0.177, p = 0.043).
Conclusion: There is a significant inter-relationship between waist circumference and hs-CRP level among apparently healthy obese adults in Kuantan, Pahang. This study suggests that assessment of hs-CRP level is beneficial to predict the risk for future cardiovascular disease event and facilitate the management of obesity in this population. A prospective clinical study is recommended to confirm the findings. |
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