α‐Glucosidase inhibitory and antioxidant activities of different ipomoea aquatica cultivars and LC–MS/MS profiling of the active cultivar

α‐Glucosidase inhibitory and antioxidant activities of different ipomoea aquatica cultivars and LC–MS/MS profiling of the active cultivar

The present study was designed to investigate the effect of Ipomoea aquatica extracted using water and methanol at various concentrations on the total phenolics, antioxidant capacity, and a-glucosidase inhibitory activities. Three I. aquatica cultivars were used in this study including the upland...

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Main Authors: Lawal, Umar, Leong, Sze Wei, Saari, Khozirah, Ismail, Intan Safinar, Khatib, Alfi, Abas, Faridah
Format: Article
Language:English
English
Published: Wiley Periodicals, Inc. 2017
Subjects:
RS Pharmacy and materia medica
Online Access:http://irep.iium.edu.my/59006/
http://irep.iium.edu.my/59006/
http://irep.iium.edu.my/59006/
http://irep.iium.edu.my/59006/1/lawal%20et%20al.%202017.pdf
http://irep.iium.edu.my/59006/6/59006_%CE%B1-Glucosidase%20Inhibitory%20and%20Antioxidant%20Activities%20of%20Different%20Ipomoea%20aquatica%20Cultivars%20_scopus.pdf
id iium-59006
recordtype eprints
spelling iium-590062018-03-09T08:07:40Z http://irep.iium.edu.my/59006/ α‐Glucosidase inhibitory and antioxidant activities of different ipomoea aquatica cultivars and LC–MS/MS profiling of the active cultivar Lawal, Umar Leong, Sze Wei Saari, Khozirah Ismail, Intan Safinar Khatib, Alfi Abas, Faridah RS Pharmacy and materia medica The present study was designed to investigate the effect of Ipomoea aquatica extracted using water and methanol at various concentrations on the total phenolics, antioxidant capacity, and a-glucosidase inhibitory activities. Three I. aquatica cultivars were used in this study including the upland type with narrow leaves (K-11), low-land aquatic types with broader shaped leaves (K-25), and bamboo-shaped leaves (K-88). The results revealed that 70% methanol extract of K-11 showed higher total phenolic content and a-glucosidase inhibitory and antioxidant activities than the other two cultivars. The phytochemical constituents in the active extract K-11 were analyzed by means of liquid chromatography coupled with diode array detection and electrospray tandem mass spectroscopy. Eighteen compounds were detected of which 13 were tentatively identified as quercetin-3-O-sophoroside, quercetin-3-O-glucoside, quercetin-3,7-di-O-glucoside, nomilinic acid glucoside, 4,5-di-O-caffeoylquinic acid, 3,5-di-O-caffeoylquinic acid, luteolin-7-glucoside and 3,4,5-tricaffeolquinic acid, fatty acid together with quercetin, and tricaffeoylquinic acid derivatives. Wiley Periodicals, Inc. 2017-01-01 Article PeerReviewed application/pdf en http://irep.iium.edu.my/59006/1/lawal%20et%20al.%202017.pdf application/pdf en http://irep.iium.edu.my/59006/6/59006_%CE%B1-Glucosidase%20Inhibitory%20and%20Antioxidant%20Activities%20of%20Different%20Ipomoea%20aquatica%20Cultivars%20_scopus.pdf Lawal, Umar and Leong, Sze Wei and Saari, Khozirah and Ismail, Intan Safinar and Khatib, Alfi and Abas, Faridah (2017) α‐Glucosidase inhibitory and antioxidant activities of different ipomoea aquatica cultivars and LC–MS/MS profiling of the active cultivar. Journal of Food Biochemistry, 41 (2). pp. 1-8. ISSN 1745-4514 http://onlinelibrary.wiley.com/doi/10.1111/jfbc.12303/abstract 10.1111/jfbc.12303
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
English
topic RS Pharmacy and materia medica
spellingShingle RS Pharmacy and materia medica
Lawal, Umar
Leong, Sze Wei
Saari, Khozirah
Ismail, Intan Safinar
Khatib, Alfi
Abas, Faridah
α‐Glucosidase inhibitory and antioxidant activities of different ipomoea aquatica cultivars and LC–MS/MS profiling of the active cultivar
description The present study was designed to investigate the effect of Ipomoea aquatica extracted using water and methanol at various concentrations on the total phenolics, antioxidant capacity, and a-glucosidase inhibitory activities. Three I. aquatica cultivars were used in this study including the upland type with narrow leaves (K-11), low-land aquatic types with broader shaped leaves (K-25), and bamboo-shaped leaves (K-88). The results revealed that 70% methanol extract of K-11 showed higher total phenolic content and a-glucosidase inhibitory and antioxidant activities than the other two cultivars. The phytochemical constituents in the active extract K-11 were analyzed by means of liquid chromatography coupled with diode array detection and electrospray tandem mass spectroscopy. Eighteen compounds were detected of which 13 were tentatively identified as quercetin-3-O-sophoroside, quercetin-3-O-glucoside, quercetin-3,7-di-O-glucoside, nomilinic acid glucoside, 4,5-di-O-caffeoylquinic acid, 3,5-di-O-caffeoylquinic acid, luteolin-7-glucoside and 3,4,5-tricaffeolquinic acid, fatty acid together with quercetin, and tricaffeoylquinic acid derivatives.
format Article
author Lawal, Umar
Leong, Sze Wei
Saari, Khozirah
Ismail, Intan Safinar
Khatib, Alfi
Abas, Faridah
author_facet Lawal, Umar
Leong, Sze Wei
Saari, Khozirah
Ismail, Intan Safinar
Khatib, Alfi
Abas, Faridah
author_sort Lawal, Umar
title α‐Glucosidase inhibitory and antioxidant activities of different ipomoea aquatica cultivars and LC–MS/MS profiling of the active cultivar
title_short α‐Glucosidase inhibitory and antioxidant activities of different ipomoea aquatica cultivars and LC–MS/MS profiling of the active cultivar
title_full α‐Glucosidase inhibitory and antioxidant activities of different ipomoea aquatica cultivars and LC–MS/MS profiling of the active cultivar
title_fullStr α‐Glucosidase inhibitory and antioxidant activities of different ipomoea aquatica cultivars and LC–MS/MS profiling of the active cultivar
title_full_unstemmed α‐Glucosidase inhibitory and antioxidant activities of different ipomoea aquatica cultivars and LC–MS/MS profiling of the active cultivar
title_sort α‐glucosidase inhibitory and antioxidant activities of different ipomoea aquatica cultivars and lc–ms/ms profiling of the active cultivar
publisher Wiley Periodicals, Inc.
publishDate 2017
url http://irep.iium.edu.my/59006/
http://irep.iium.edu.my/59006/
http://irep.iium.edu.my/59006/
http://irep.iium.edu.my/59006/1/lawal%20et%20al.%202017.pdf
http://irep.iium.edu.my/59006/6/59006_%CE%B1-Glucosidase%20Inhibitory%20and%20Antioxidant%20Activities%20of%20Different%20Ipomoea%20aquatica%20Cultivars%20_scopus.pdf
first_indexed 2023-09-18T21:23:31Z
last_indexed 2023-09-18T21:23:31Z
_version_ 1777412039520550912

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