Statins and ischaemia reperfusion injury: a molecular biological review
The 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase inhibitors (statins) are a class of drug used to lower low-density lipoprotein (LDL) levels. However, in recent years, statins have been shown to possess a pleiotropic effect beyond its cholesterol lowering ability, including attenuating the e...
| Main Authors: | , |
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| Format: | Article |
| Language: | English English |
| Published: |
Bentham Science Publishers B.V.
2010
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/59118/ http://irep.iium.edu.my/59118/ http://irep.iium.edu.my/59118/ http://irep.iium.edu.my/59118/1/Statins%20and%20ischaemia%20reperfusion%20injury%20a%20molecular%20biological%20review.pdf http://irep.iium.edu.my/59118/7/59118_Statins%20and%20ischaemia%20reperfusion%20injury_scopus.pdf |
| Summary: | The 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase inhibitors (statins) are a class of drug used to
lower low-density lipoprotein (LDL) levels. However, in recent years, statins have been shown to possess a pleiotropic effect beyond its cholesterol lowering ability, including attenuating the effect of ischaemia reperfusion injury. This review considers the biomolecular processes that may lead to this beneficial effect. |
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