Statins and ischaemia reperfusion injury: a molecular biological review

Statins and ischaemia reperfusion injury: a molecular biological review

The 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase inhibitors (statins) are a class of drug used to lower low-density lipoprotein (LDL) levels. However, in recent years, statins have been shown to possess a pleiotropic effect beyond its cholesterol lowering ability, including attenuating the e...

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Bibliographic Details
Main Authors: Abdul Rahman, Mohd Norhisham Azmi, Chetter, Ian Clifford
Format: Article
Language:English
English
Published: Bentham Science Publishers B.V. 2010
Subjects:
RD Surgery
Online Access:http://irep.iium.edu.my/59118/
http://irep.iium.edu.my/59118/
http://irep.iium.edu.my/59118/
http://irep.iium.edu.my/59118/1/Statins%20and%20ischaemia%20reperfusion%20injury%20a%20molecular%20biological%20review.pdf
http://irep.iium.edu.my/59118/7/59118_Statins%20and%20ischaemia%20reperfusion%20injury_scopus.pdf
id iium-59118
recordtype eprints
spelling iium-591182017-11-06T07:28:31Z http://irep.iium.edu.my/59118/ Statins and ischaemia reperfusion injury: a molecular biological review Abdul Rahman, Mohd Norhisham Azmi Chetter, Ian Clifford RD Surgery The 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase inhibitors (statins) are a class of drug used to lower low-density lipoprotein (LDL) levels. However, in recent years, statins have been shown to possess a pleiotropic effect beyond its cholesterol lowering ability, including attenuating the effect of ischaemia reperfusion injury. This review considers the biomolecular processes that may lead to this beneficial effect. Bentham Science Publishers B.V. 2010-12 Article PeerReviewed application/pdf en http://irep.iium.edu.my/59118/1/Statins%20and%20ischaemia%20reperfusion%20injury%20a%20molecular%20biological%20review.pdf application/pdf en http://irep.iium.edu.my/59118/7/59118_Statins%20and%20ischaemia%20reperfusion%20injury_scopus.pdf Abdul Rahman, Mohd Norhisham Azmi and Chetter, Ian Clifford (2010) Statins and ischaemia reperfusion injury: a molecular biological review. Current Vascular Pharmacology, 8 (6). pp. 831-835. ISSN 1570-1611 E-ISSN 1875-6212 https://benthamscience.com/journals/current-vascular-pharmacology/ 10.2174/157016110793563780
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
English
topic RD Surgery
spellingShingle RD Surgery
Abdul Rahman, Mohd Norhisham Azmi
Chetter, Ian Clifford
Statins and ischaemia reperfusion injury: a molecular biological review
description The 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reductase inhibitors (statins) are a class of drug used to lower low-density lipoprotein (LDL) levels. However, in recent years, statins have been shown to possess a pleiotropic effect beyond its cholesterol lowering ability, including attenuating the effect of ischaemia reperfusion injury. This review considers the biomolecular processes that may lead to this beneficial effect.
format Article
author Abdul Rahman, Mohd Norhisham Azmi
Chetter, Ian Clifford
author_facet Abdul Rahman, Mohd Norhisham Azmi
Chetter, Ian Clifford
author_sort Abdul Rahman, Mohd Norhisham Azmi
title Statins and ischaemia reperfusion injury: a molecular biological review
title_short Statins and ischaemia reperfusion injury: a molecular biological review
title_full Statins and ischaemia reperfusion injury: a molecular biological review
title_fullStr Statins and ischaemia reperfusion injury: a molecular biological review
title_full_unstemmed Statins and ischaemia reperfusion injury: a molecular biological review
title_sort statins and ischaemia reperfusion injury: a molecular biological review
publisher Bentham Science Publishers B.V.
publishDate 2010
url http://irep.iium.edu.my/59118/
http://irep.iium.edu.my/59118/
http://irep.iium.edu.my/59118/
http://irep.iium.edu.my/59118/1/Statins%20and%20ischaemia%20reperfusion%20injury%20a%20molecular%20biological%20review.pdf
http://irep.iium.edu.my/59118/7/59118_Statins%20and%20ischaemia%20reperfusion%20injury_scopus.pdf
first_indexed 2023-09-18T21:23:41Z
last_indexed 2023-09-18T21:23:41Z
_version_ 1777412049977999360

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