Multivariate calibration of antioxidant activity of M. charantia fruits and its fourier transform infrared spectroscopy based fingerprinting

Momordica charantia is widely consumed edible fruit. The food and pharmaceutical industries use it as a natural antioxidant. However, the quality control of M. charantia-based medicinal products is questionable due to the complexity of metabolites in this fruit. Hence, this study has developed a sta...

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Main Authors:	Khatib, Alfi, Bakhtiar, M. Taher
Format:	Monograph
Language:	English
Published:	2017
Subjects:	Q Science (General)
Online Access:	http://irep.iium.edu.my/59282/ http://irep.iium.edu.my/59282/1/RIGS%20MChanratia_Final%20report.pdf

id	iium-59282
recordtype	eprints
spelling	iium-592822017-12-25T13:27:37Z http://irep.iium.edu.my/59282/ Multivariate calibration of antioxidant activity of M. charantia fruits and its fourier transform infrared spectroscopy based fingerprinting Khatib, Alfi Bakhtiar, M. Taher Q Science (General) Momordica charantia is widely consumed edible fruit. The food and pharmaceutical industries use it as a natural antioxidant. However, the quality control of M. charantia-based medicinal products is questionable due to the complexity of metabolites in this fruit. Hence, this study has developed a statistical model in predicting the antioxidant value through the 2, 2-diphenyl-1 picrylhydrazyl radical scavenging activity and ferric reducing antioxidant power based on infrared spectroscopy with attenuated total reflectance. This technique was reliably used for quality control. Six ethanol extracts (0, 20, 40, 60, 80, and 100% in water) of this plant’s fruit were prepared. The radical scavenging and ferric reducing antioxidant power activities were measured and the chemical profiling of the extracts was fingerprinted by infrared spectroscopy between 4,000 and 600 cm−1 at a resolution of 4 cm−1. Statistical analysis was developed by correlating the bioactivity and infrared spectra of each extract using orthogonal partial least square discriminant analysis. The C–N, C=O, C–O, C–H, and OH infrared signals were positively correlated with biological activity. The antioxidant activity of the fruit of M. charantia may be due to the presence of several antioxidants that work synergistically. 2017-11-10 Monograph NonPeerReviewed application/pdf en http://irep.iium.edu.my/59282/1/RIGS%20MChanratia_Final%20report.pdf Khatib, Alfi and Bakhtiar, M. Taher (2017) Multivariate calibration of antioxidant activity of M. charantia fruits and its fourier transform infrared spectroscopy based fingerprinting. Project Report. UNSPECIFIED. (Unpublished)
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	Q Science (General)
spellingShingle	Q Science (General) Khatib, Alfi Bakhtiar, M. Taher Multivariate calibration of antioxidant activity of M. charantia fruits and its fourier transform infrared spectroscopy based fingerprinting
description	Momordica charantia is widely consumed edible fruit. The food and pharmaceutical industries use it as a natural antioxidant. However, the quality control of M. charantia-based medicinal products is questionable due to the complexity of metabolites in this fruit. Hence, this study has developed a statistical model in predicting the antioxidant value through the 2, 2-diphenyl-1 picrylhydrazyl radical scavenging activity and ferric reducing antioxidant power based on infrared spectroscopy with attenuated total reflectance. This technique was reliably used for quality control. Six ethanol extracts (0, 20, 40, 60, 80, and 100% in water) of this plant’s fruit were prepared. The radical scavenging and ferric reducing antioxidant power activities were measured and the chemical profiling of the extracts was fingerprinted by infrared spectroscopy between 4,000 and 600 cm−1 at a resolution of 4 cm−1. Statistical analysis was developed by correlating the bioactivity and infrared spectra of each extract using orthogonal partial least square discriminant analysis. The C–N, C=O, C–O, C–H, and OH infrared signals were positively correlated with biological activity. The antioxidant activity of the fruit of M. charantia may be due to the presence of several antioxidants that work synergistically.
format	Monograph
author	Khatib, Alfi Bakhtiar, M. Taher
author_facet	Khatib, Alfi Bakhtiar, M. Taher
author_sort	Khatib, Alfi
title	Multivariate calibration of antioxidant activity of M. charantia fruits and its fourier transform infrared spectroscopy based fingerprinting
title_short	Multivariate calibration of antioxidant activity of M. charantia fruits and its fourier transform infrared spectroscopy based fingerprinting
title_full	Multivariate calibration of antioxidant activity of M. charantia fruits and its fourier transform infrared spectroscopy based fingerprinting
title_fullStr	Multivariate calibration of antioxidant activity of M. charantia fruits and its fourier transform infrared spectroscopy based fingerprinting
title_full_unstemmed	Multivariate calibration of antioxidant activity of M. charantia fruits and its fourier transform infrared spectroscopy based fingerprinting
title_sort	multivariate calibration of antioxidant activity of m. charantia fruits and its fourier transform infrared spectroscopy based fingerprinting
publishDate	2017
url	http://irep.iium.edu.my/59282/ http://irep.iium.edu.my/59282/1/RIGS%20MChanratia_Final%20report.pdf
first_indexed	2023-09-18T21:23:58Z
last_indexed	2023-09-18T21:23:58Z
_version_	1777412067130605568

Multivariate calibration of antioxidant activity of M. charantia fruits and its fourier transform infrared spectroscopy based fingerprinting

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