Influence of sodium on the properties of sol-gel derived hydroxyapatite powder and porous scaffolds

This study investigates the properties of sol-gel derived sodium (Na)-doped hydroxyapatite (HA) powder. Different amounts of Na (1, 5, 10 and 15 mol%) were prepared and the sintered bodies were characterized to determine the current phases, microstructural evolution and mechanical properties. X-ra...

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Main Authors: Sopyan, Lis, Pusparini, Erlani, Subramaniam, Ramesh T., Tan, Chou Yong, Ching, Yernchee, Wong, Yinhow, Zainal Abidin, Nor Ishida, Chandran, Hari, Ramesh, S., Bang, Lethi
Format: Article
Language:English
English
Published: 2017
Subjects:
Online Access:http://irep.iium.edu.my/59503/
http://irep.iium.edu.my/59503/
http://irep.iium.edu.my/59503/
http://irep.iium.edu.my/59503/1/Ceram%20Inter-43-12263%20%282017%29.pdf
http://irep.iium.edu.my/59503/7/59503_Influence%20of%20sodium%20on%20the%20properties%20_scopus.pdf
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spelling iium-595032017-11-21T05:54:06Z http://irep.iium.edu.my/59503/ Influence of sodium on the properties of sol-gel derived hydroxyapatite powder and porous scaffolds Sopyan, Lis Pusparini, Erlani Subramaniam, Ramesh T. Tan, Chou Yong Ching, Yernchee Wong, Yinhow Zainal Abidin, Nor Ishida Chandran, Hari Ramesh, S. Bang, Lethi TA164 Bioengineering TA401 Materials of engineering and construction This study investigates the properties of sol-gel derived sodium (Na)-doped hydroxyapatite (HA) powder. Different amounts of Na (1, 5, 10 and 15 mol%) were prepared and the sintered bodies were characterized to determine the current phases, microstructural evolution and mechanical properties. X-ray diffraction analysis reveals that a phase pure HA of crystallite sizes, which varied from 35 nm to 65 nm, was obtained in the synthesized powder after calcining from 500 °C to 1000 °C. Scanning electron microscopy examination shows evidence of larger particle sizes, particularly in samples that contain higher amounts of Na concentration. The resultant powders were subsequently used to prepare porous NA-doped HA bodies through a polymeric sponge method. The addition of 5% Na resulted in a porous body with 27% porosity and was beneficial in enhancing the compressive strength of HA 17-fold compared with undoped HA. The prepared scaffold also shows suitable pore interconnectivity with pore sizes that vary between 100 and 300 μm which is suitable for use as porous bone substitutes. 2017 Article PeerReviewed application/pdf en http://irep.iium.edu.my/59503/1/Ceram%20Inter-43-12263%20%282017%29.pdf application/pdf en http://irep.iium.edu.my/59503/7/59503_Influence%20of%20sodium%20on%20the%20properties%20_scopus.pdf Sopyan, Lis and Pusparini, Erlani and Subramaniam, Ramesh T. and Tan, Chou Yong and Ching, Yernchee and Wong, Yinhow and Zainal Abidin, Nor Ishida and Chandran, Hari and Ramesh, S. and Bang, Lethi (2017) Influence of sodium on the properties of sol-gel derived hydroxyapatite powder and porous scaffolds. Ceramics International, 43 (15). pp. 12263-12269. ISSN 0272-8842 http://www.sciencedirect.com/science/article/pii/S0272884217313044 10.1016/j.ceramint.2017.06.088
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
English
topic TA164 Bioengineering
TA401 Materials of engineering and construction
spellingShingle TA164 Bioengineering
TA401 Materials of engineering and construction
Sopyan, Lis
Pusparini, Erlani
Subramaniam, Ramesh T.
Tan, Chou Yong
Ching, Yernchee
Wong, Yinhow
Zainal Abidin, Nor Ishida
Chandran, Hari
Ramesh, S.
Bang, Lethi
Influence of sodium on the properties of sol-gel derived hydroxyapatite powder and porous scaffolds
description This study investigates the properties of sol-gel derived sodium (Na)-doped hydroxyapatite (HA) powder. Different amounts of Na (1, 5, 10 and 15 mol%) were prepared and the sintered bodies were characterized to determine the current phases, microstructural evolution and mechanical properties. X-ray diffraction analysis reveals that a phase pure HA of crystallite sizes, which varied from 35 nm to 65 nm, was obtained in the synthesized powder after calcining from 500 °C to 1000 °C. Scanning electron microscopy examination shows evidence of larger particle sizes, particularly in samples that contain higher amounts of Na concentration. The resultant powders were subsequently used to prepare porous NA-doped HA bodies through a polymeric sponge method. The addition of 5% Na resulted in a porous body with 27% porosity and was beneficial in enhancing the compressive strength of HA 17-fold compared with undoped HA. The prepared scaffold also shows suitable pore interconnectivity with pore sizes that vary between 100 and 300 μm which is suitable for use as porous bone substitutes.
format Article
author Sopyan, Lis
Pusparini, Erlani
Subramaniam, Ramesh T.
Tan, Chou Yong
Ching, Yernchee
Wong, Yinhow
Zainal Abidin, Nor Ishida
Chandran, Hari
Ramesh, S.
Bang, Lethi
author_facet Sopyan, Lis
Pusparini, Erlani
Subramaniam, Ramesh T.
Tan, Chou Yong
Ching, Yernchee
Wong, Yinhow
Zainal Abidin, Nor Ishida
Chandran, Hari
Ramesh, S.
Bang, Lethi
author_sort Sopyan, Lis
title Influence of sodium on the properties of sol-gel derived hydroxyapatite powder and porous scaffolds
title_short Influence of sodium on the properties of sol-gel derived hydroxyapatite powder and porous scaffolds
title_full Influence of sodium on the properties of sol-gel derived hydroxyapatite powder and porous scaffolds
title_fullStr Influence of sodium on the properties of sol-gel derived hydroxyapatite powder and porous scaffolds
title_full_unstemmed Influence of sodium on the properties of sol-gel derived hydroxyapatite powder and porous scaffolds
title_sort influence of sodium on the properties of sol-gel derived hydroxyapatite powder and porous scaffolds
publishDate 2017
url http://irep.iium.edu.my/59503/
http://irep.iium.edu.my/59503/
http://irep.iium.edu.my/59503/
http://irep.iium.edu.my/59503/1/Ceram%20Inter-43-12263%20%282017%29.pdf
http://irep.iium.edu.my/59503/7/59503_Influence%20of%20sodium%20on%20the%20properties%20_scopus.pdf
first_indexed 2023-09-18T21:24:18Z
last_indexed 2023-09-18T21:24:18Z
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