Functionalization of medium-chain-length poly(3-hydroxyalkanoates) as amphiphilic material by graft copolymerization with glycerol 1,3-diglycerolate diacrylate and its mechanism
Glycerol 1,3-diglycerolate diacrylate (GDD) was graft copolymerized onto poly(3-hydroxyoctanoate-co-3- hydroxyhexanoate) P(3HO-co-3HHX) to render the latter more hydrophilic. Grafting of P(3HO-co-3HHX) backbone was performed using benzoyl peroxide as free radical initiator in homogenous acetone so...
| Main Authors: | , |
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| Format: | Article |
| Language: | English English |
| Published: |
Taylor & Francis
2017
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/60340/ http://irep.iium.edu.my/60340/ http://irep.iium.edu.my/60340/ http://irep.iium.edu.my/60340/1/60340_Functionalization%20of%20medium-chain-length%20_article.pdf http://irep.iium.edu.my/60340/2/60340_Functionalization%20of%20medium-chain-length%20_scopus.pdf |
| Summary: | Glycerol 1,3-diglycerolate diacrylate (GDD) was graft copolymerized onto poly(3-hydroxyoctanoate-co-3-
hydroxyhexanoate) P(3HO-co-3HHX) to render the latter more hydrophilic. Grafting of P(3HO-co-3HHX)
backbone was performed using benzoyl peroxide as free radical initiator in homogenous acetone solution.
The graft copolymer of P(3HO-co-3HHX)-g-GDD was characterized using spectroscopic and thermal
methods. The presence of GDD monomer in the grafted P(3HO-co-3HHX) materials linked through
covalent bond was indicated by spectroscopic analyses. Different parameters affecting the graft yield viz.
monomer concentration, initiator concentration, temperature and reaction time were also investigated.
Water uptake measurement showed that P(3HO-co-3HHX)-g-GDD copolymer became more hydrophilic as
the GDD concentration in the copolymer increased. Introduction of hydroxyl groups via grafted GDD
monomers improved the wettability and imparted amphiphilicity to the graft copolymer, thus potentially
improving their facility for cellular interaction. Thermal stability of grafted copolymer reduced with
increased grafting yield. The activation energy, Ea, for the graft copolymerization was calculated at » 51 kJ
mol¡1. Mechanism of grafting reaction was also proposed. |
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