Risk factors for anti tuberculous drugs induced hepatitis: a prospective survey from a chest clinic in a general hospital
A prospective survey on 14 consecutive cases with tuberculous drug induced hepatitis was done at our chest clinic in a state general hospital over a period of 15 months. There were 30 controls chosen randomly from the chest clinic register. The cases had lower mean body mass index (P<0.008), seru...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Malaysian Medical Associations
2004
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/6035/ http://irep.iium.edu.my/6035/ http://irep.iium.edu.my/6035/1/Risk_Factors_for_Anti_Tuberculous_Drugs_Induced.pdf |
| Summary: | A prospective survey on 14 consecutive cases with tuberculous drug induced hepatitis was done at our chest clinic in a state general hospital over a period of 15 months. There were 30 controls chosen randomly from the chest clinic register. The cases had lower mean body mass index (P<0.008), serum albumin (P<0.005) and higher serum globulin (P<0.04). Serum liver transaminases and total bilirubin rose significantly during the acute episode of drug induced hepatitis. Among the risk factors studied, only chronic hepatitis B carrier status was found to be more prevalent among the cases. There was one death (7.1%) over the whole study period. |
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