The relationship between symptomatic assessment and clinical signs of dryness in dry eye subjects

The relationship between symptomatic assessment and clinical signs of dryness in dry eye subjects

Introduction: There was no previous study to assess relationship between dry eye symptoms and signs in the local population. The purpose of this study is to evaluate the relationship of symptomatic assessment and clinical signs of dryness in dry eye subjects. Materials and method: A Cross-section...

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Main Authors: Ithnin, Mohd. Hafidz, Ariffin, Azrin Esmady, Mohd Kamal, Khairidzan
Format: Article
Language:English
Published: IIUM Press 2017
Subjects:
RE Ophthalmology
Online Access:http://irep.iium.edu.my/60782/
http://irep.iium.edu.my/60782/
http://irep.iium.edu.my/60782/1/The%20relationship%20between%20symptomatic%20assessment%20and%20clinical%20signs%20of%20dryness%20in%20dry%20eye%20subjects.pdf
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spelling iium-607822017-12-31T15:30:03Z http://irep.iium.edu.my/60782/ The relationship between symptomatic assessment and clinical signs of dryness in dry eye subjects Ithnin, Mohd. Hafidz Ariffin, Azrin Esmady Mohd Kamal, Khairidzan RE Ophthalmology Introduction: There was no previous study to assess relationship between dry eye symptoms and signs in the local population. The purpose of this study is to evaluate the relationship of symptomatic assessment and clinical signs of dryness in dry eye subjects. Materials and method: A Cross-sectional study with convenient sampling involving 321 subjects with 642 eyes was done. Subjects were divided into non-dry eye (NDE) and dry eye (DE) groups. The division of NDE and DE groups were done using two types of classification. In Classification 1(symptoms-based), DE was defined if the score of Ocular Surface Disease Index (OSDI) score was more than 33. The value of tear film break-up time (TFBUT) less than 5 seconds and Schirmer test with anaesthesia (STA) less than 5mm/5 minutes were considered as DE for Classification 2 (signs based). Results: There were poor correlations between OSDI and clinical signs of dryness in all subjects involved (p > 0.05). Similar findings were also noted within NDE subjects in Classification 1 and Classification 2. OSDI score was also not significantly correlated with the signs of dryness within DE subjects except with ocular protection index (OPI) (r = -0.14, p = 0.047) in Classification 1 and with conjunctival lissamine green staining (CLGS)(r = 0.23, p = 0.040) in Classification 2. Conclusion: There were no significant correlation between the symptoms of dry eye and the clinical signs of dry eye. Therefore, the clinical diagnosis of dry eye can be made based on either just on the symptoms or the signs. IIUM Press 2017-08-10 Article PeerReviewed application/pdf en http://irep.iium.edu.my/60782/1/The%20relationship%20between%20symptomatic%20assessment%20and%20clinical%20signs%20of%20dryness%20in%20dry%20eye%20subjects.pdf Ithnin, Mohd. Hafidz and Ariffin, Azrin Esmady and Mohd Kamal, Khairidzan (2017) The relationship between symptomatic assessment and clinical signs of dryness in dry eye subjects. International Medical Journal Malaysiayia, 16 (supp issue 1). p. 47. ISSN 1823-4631 E-ISSN 1823-4631 http://iiumedic.net/imjm/v1/about-imjm/
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
topic RE Ophthalmology
spellingShingle RE Ophthalmology
Ithnin, Mohd. Hafidz
Ariffin, Azrin Esmady
Mohd Kamal, Khairidzan
The relationship between symptomatic assessment and clinical signs of dryness in dry eye subjects
description Introduction: There was no previous study to assess relationship between dry eye symptoms and signs in the local population. The purpose of this study is to evaluate the relationship of symptomatic assessment and clinical signs of dryness in dry eye subjects. Materials and method: A Cross-sectional study with convenient sampling involving 321 subjects with 642 eyes was done. Subjects were divided into non-dry eye (NDE) and dry eye (DE) groups. The division of NDE and DE groups were done using two types of classification. In Classification 1(symptoms-based), DE was defined if the score of Ocular Surface Disease Index (OSDI) score was more than 33. The value of tear film break-up time (TFBUT) less than 5 seconds and Schirmer test with anaesthesia (STA) less than 5mm/5 minutes were considered as DE for Classification 2 (signs based). Results: There were poor correlations between OSDI and clinical signs of dryness in all subjects involved (p > 0.05). Similar findings were also noted within NDE subjects in Classification 1 and Classification 2. OSDI score was also not significantly correlated with the signs of dryness within DE subjects except with ocular protection index (OPI) (r = -0.14, p = 0.047) in Classification 1 and with conjunctival lissamine green staining (CLGS)(r = 0.23, p = 0.040) in Classification 2. Conclusion: There were no significant correlation between the symptoms of dry eye and the clinical signs of dry eye. Therefore, the clinical diagnosis of dry eye can be made based on either just on the symptoms or the signs.
format Article
author Ithnin, Mohd. Hafidz
Ariffin, Azrin Esmady
Mohd Kamal, Khairidzan
author_facet Ithnin, Mohd. Hafidz
Ariffin, Azrin Esmady
Mohd Kamal, Khairidzan
author_sort Ithnin, Mohd. Hafidz
title The relationship between symptomatic assessment and clinical signs of dryness in dry eye subjects
title_short The relationship between symptomatic assessment and clinical signs of dryness in dry eye subjects
title_full The relationship between symptomatic assessment and clinical signs of dryness in dry eye subjects
title_fullStr The relationship between symptomatic assessment and clinical signs of dryness in dry eye subjects
title_full_unstemmed The relationship between symptomatic assessment and clinical signs of dryness in dry eye subjects
title_sort relationship between symptomatic assessment and clinical signs of dryness in dry eye subjects
publisher IIUM Press
publishDate 2017
url http://irep.iium.edu.my/60782/
http://irep.iium.edu.my/60782/
http://irep.iium.edu.my/60782/1/The%20relationship%20between%20symptomatic%20assessment%20and%20clinical%20signs%20of%20dryness%20in%20dry%20eye%20subjects.pdf
first_indexed 2023-09-18T21:26:10Z
last_indexed 2023-09-18T21:26:10Z
_version_ 1777412205566754816

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