Evaluation of thresholding techniques on 3D fractal dimension MRI images
Fractal Analysis (FA) application in medical field has been used to measure the occurrence of changes in the brain complexity for some diseased and normal aging brain. Within FA, there is Fractal Dimension (FD) which is an index of structural complexity. FD methods were classified into three major c...
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Medwell Publications
2017
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iium-614202018-04-25T03:16:04Z http://irep.iium.edu.my/61420/ Evaluation of thresholding techniques on 3D fractal dimension MRI images Jamaludin, Iqbal Che Azemin, Mohd Zulfaezal Musa, Liyana Sapuan, Abdul HaliM Abdul Majid, Zafri Azran Ahmad, Azmir A. Rahman, Nor Azlina Sideek, Mohamed Arshad QA75 Electronic computers. Computer science QM Human anatomy Fractal Analysis (FA) application in medical field has been used to measure the occurrence of changes in the brain complexity for some diseased and normal aging brain. Within FA, there is Fractal Dimension (FD) which is an index of structural complexity. FD methods were classified into three major categories which are box-counting method, variance method and spectral method. Here in this study we used box-counting method to measure our FD due to its directness and automatic computability capabilities. We evaluated the impact of different thresholding techniques when quantifying the FD. We applied three different thresholding techniques on our brain MRI images: Otsu’s method, midpoint method and hysteresis method. A total of 27 subjects (14 males and 13 females) aged ranging between 21-25 years old were voluntarily participated. The process of thresholding the images and computation of the FD values were done under MATLAB. There was a statistically significant difference between groups of thresholding techniques as determined by Friedman test with χ(2) = 48.667 and p<0.001. Post-hoc Wilcoxon-signed ranked test with Bonferroni correction done where the p-value was set to 0.017. All three group pairs (midpoint vs. Otsu’s, midpoint vs. hysteresis and hysteresis vs. Otsu’s) were statistically significant different with p<0.001. Pearson’s correlation showed moderate correlation (r = 0.446, p = 0.02) between hysteresis and Otsu’s. Spearman correlation showed weak correlation which is not significant (r = 0.256, p = 0.198) for midpoint vs. Otsu’s and (r = 0.252, p = 0.204) for midpoint vs. hysteresis. In conclusion, different thresholding techniques do have impact on FD values but with moderate correlation between them. Medwell Publications 2017 Article PeerReviewed application/pdf en http://irep.iium.edu.my/61420/1/2017%20iSHAMS.pdf application/pdf en http://irep.iium.edu.my/61420/11/61420_Evaluation%20of%20thresholding%20techniques_scopus.pdf application/pdf en http://irep.iium.edu.my/61420/16/61420_Evaluation%20of%20thresholding%20techniques%20on%203D_scopus.pdf Jamaludin, Iqbal and Che Azemin, Mohd Zulfaezal and Musa, Liyana and Sapuan, Abdul HaliM and Abdul Majid, Zafri Azran and Ahmad, Azmir and A. Rahman, Nor Azlina and Sideek, Mohamed Arshad (2017) Evaluation of thresholding techniques on 3D fractal dimension MRI images. Journal of Engineering and Applied Sciences, 12 (Special Issue (3)). pp. 6387-6392. ISSN 1816-949X E-ISSN 1818-7803 http://docsdrive.com/pdfs/medwelljournals/jeasci/2017/6387-6392.pdf 10.3923/jeasci.2017.6387.6392 |
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QA75 Electronic computers. Computer science QM Human anatomy Jamaludin, Iqbal Che Azemin, Mohd Zulfaezal Musa, Liyana Sapuan, Abdul HaliM Abdul Majid, Zafri Azran Ahmad, Azmir A. Rahman, Nor Azlina Sideek, Mohamed Arshad Evaluation of thresholding techniques on 3D fractal dimension MRI images |
description |
Fractal Analysis (FA) application in medical field has been used to measure the occurrence of changes in the brain complexity for some diseased and normal aging brain. Within FA, there is Fractal Dimension (FD) which is an index of structural complexity. FD methods were classified into three major categories which are box-counting method, variance method and spectral method. Here in this study we used box-counting method to measure our FD due to its directness and automatic computability capabilities. We evaluated the impact of different thresholding techniques when quantifying the FD. We applied three different thresholding techniques on our brain MRI images: Otsu’s method, midpoint method and hysteresis method. A total of 27 subjects (14 males and 13 females) aged ranging between 21-25 years old were voluntarily participated. The process of thresholding the images and computation of the FD values were done under MATLAB. There was a statistically significant difference between groups of thresholding techniques as determined by Friedman test with χ(2) = 48.667 and p<0.001. Post-hoc Wilcoxon-signed ranked test with Bonferroni correction done where the p-value was set to 0.017. All three group pairs (midpoint vs. Otsu’s, midpoint vs. hysteresis and hysteresis vs. Otsu’s) were statistically significant different with p<0.001. Pearson’s correlation showed moderate correlation (r = 0.446, p = 0.02) between hysteresis and Otsu’s. Spearman correlation showed weak correlation which is not significant (r = 0.256, p = 0.198) for midpoint vs. Otsu’s and (r = 0.252, p = 0.204) for midpoint vs. hysteresis. In conclusion, different thresholding techniques do have impact on FD values but with moderate correlation between them. |
format |
Article |
author |
Jamaludin, Iqbal Che Azemin, Mohd Zulfaezal Musa, Liyana Sapuan, Abdul HaliM Abdul Majid, Zafri Azran Ahmad, Azmir A. Rahman, Nor Azlina Sideek, Mohamed Arshad |
author_facet |
Jamaludin, Iqbal Che Azemin, Mohd Zulfaezal Musa, Liyana Sapuan, Abdul HaliM Abdul Majid, Zafri Azran Ahmad, Azmir A. Rahman, Nor Azlina Sideek, Mohamed Arshad |
author_sort |
Jamaludin, Iqbal |
title |
Evaluation of thresholding techniques on 3D fractal dimension MRI images |
title_short |
Evaluation of thresholding techniques on 3D fractal dimension MRI images |
title_full |
Evaluation of thresholding techniques on 3D fractal dimension MRI images |
title_fullStr |
Evaluation of thresholding techniques on 3D fractal dimension MRI images |
title_full_unstemmed |
Evaluation of thresholding techniques on 3D fractal dimension MRI images |
title_sort |
evaluation of thresholding techniques on 3d fractal dimension mri images |
publisher |
Medwell Publications |
publishDate |
2017 |
url |
http://irep.iium.edu.my/61420/ http://irep.iium.edu.my/61420/ http://irep.iium.edu.my/61420/ http://irep.iium.edu.my/61420/1/2017%20iSHAMS.pdf http://irep.iium.edu.my/61420/11/61420_Evaluation%20of%20thresholding%20techniques_scopus.pdf http://irep.iium.edu.my/61420/16/61420_Evaluation%20of%20thresholding%20techniques%20on%203D_scopus.pdf |
first_indexed |
2023-09-18T21:27:07Z |
last_indexed |
2023-09-18T21:27:07Z |
_version_ |
1777412266165010432 |