Formulation and characterization of cosmetic cream incorporating piper Betle Linn. extract

INTRODUCTION: Piper betle Linn. is an evergreen and perennial plant with glossy heart-shaped leaves which contains various biologically active compounds. Hydroxychavicol is a phenolic compound found in Piper betle leaves which exhibits many potential biological activities such as antimicrobial, anti...

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Main Authors:	Hanif, Nadzira, Doolaanea, Abd Almonem, Ab. Hadi, Hazrina
Format:	Conference or Workshop Item
Language:	English
Published:	2017
Subjects:	RS Pharmacy and materia medica
Online Access:	http://irep.iium.edu.my/61757/ http://irep.iium.edu.my/61757/17/61757_Formulation%20and%20Characterization%20of%20Cosmetic%20Cream_complete.pdf

id	iium-61757
recordtype	eprints
spelling	iium-617572018-06-29T03:27:20Z http://irep.iium.edu.my/61757/ Formulation and characterization of cosmetic cream incorporating piper Betle Linn. extract Hanif, Nadzira Doolaanea, Abd Almonem Ab. Hadi, Hazrina RS Pharmacy and materia medica INTRODUCTION: Piper betle Linn. is an evergreen and perennial plant with glossy heart-shaped leaves which contains various biologically active compounds. Hydroxychavicol is a phenolic compound found in Piper betle leaves which exhibits many potential biological activities such as antimicrobial, antioxidant, anti-inflammatory and anti-tyrosinase.OBJECTIVES: The study aimed to formulate cosmetic cream incorporating Piper betle extract and to characterize the developed cream.METHODS: The cosmetic cream containing 0.02% Piper betle extract was developed by incorporating three phase ingredients include aqueous phase (75.2%), oil phase (20.8%) and cooling phase (4.0%). O/W emulsion was prepared by adding aqueous phase into oil phase through a combination process of heating up to 75℃ and homogenization at 3500 rpm. The cream formulation was characterized for organoleptic properties, pH, particle size, zeta potential, rheological behaviour and microbial limit test.RESULTS: For organoleptic properties, the cream has an off white color, pleasant odour, smooth texture and no phase separation. The cream formulation has a pH value of 5.39 ± 0.03 which was near to skin pH (4.5-5.5), smaller particle size of 3.73 ± 0.01 µm and polydispersity index of 0.56 ± 0.11, negatively zeta potential of -57.53 ± 1.47 mV and exhibited non-Newtonian behavior in which viscosity decreases when shear rate increases. The cream has no growth of viable microorganisms, yeasts and fungi.CONCLUSION: Based on physical characterization, the cream containing 0.02% Piper betle extract is regarded as a stable formulation with acceptable organoleptic properties.Keywords: Characterization, cream, formulation, oil in water emulsion, Piper betle Linn. 2017 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/61757/17/61757_Formulation%20and%20Characterization%20of%20Cosmetic%20Cream_complete.pdf Hanif, Nadzira and Doolaanea, Abd Almonem and Ab. Hadi, Hazrina (2017) Formulation and characterization of cosmetic cream incorporating piper Betle Linn. extract. In: Malaysia Pharmaceutical Society Conference 2017, 3-5 November, 2017, Penang, Malaysia.
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RS Pharmacy and materia medica
spellingShingle	RS Pharmacy and materia medica Hanif, Nadzira Doolaanea, Abd Almonem Ab. Hadi, Hazrina Formulation and characterization of cosmetic cream incorporating piper Betle Linn. extract
description	INTRODUCTION: Piper betle Linn. is an evergreen and perennial plant with glossy heart-shaped leaves which contains various biologically active compounds. Hydroxychavicol is a phenolic compound found in Piper betle leaves which exhibits many potential biological activities such as antimicrobial, antioxidant, anti-inflammatory and anti-tyrosinase.OBJECTIVES: The study aimed to formulate cosmetic cream incorporating Piper betle extract and to characterize the developed cream.METHODS: The cosmetic cream containing 0.02% Piper betle extract was developed by incorporating three phase ingredients include aqueous phase (75.2%), oil phase (20.8%) and cooling phase (4.0%). O/W emulsion was prepared by adding aqueous phase into oil phase through a combination process of heating up to 75℃ and homogenization at 3500 rpm. The cream formulation was characterized for organoleptic properties, pH, particle size, zeta potential, rheological behaviour and microbial limit test.RESULTS: For organoleptic properties, the cream has an off white color, pleasant odour, smooth texture and no phase separation. The cream formulation has a pH value of 5.39 ± 0.03 which was near to skin pH (4.5-5.5), smaller particle size of 3.73 ± 0.01 µm and polydispersity index of 0.56 ± 0.11, negatively zeta potential of -57.53 ± 1.47 mV and exhibited non-Newtonian behavior in which viscosity decreases when shear rate increases. The cream has no growth of viable microorganisms, yeasts and fungi.CONCLUSION: Based on physical characterization, the cream containing 0.02% Piper betle extract is regarded as a stable formulation with acceptable organoleptic properties.Keywords: Characterization, cream, formulation, oil in water emulsion, Piper betle Linn.
format	Conference or Workshop Item
author	Hanif, Nadzira Doolaanea, Abd Almonem Ab. Hadi, Hazrina
author_facet	Hanif, Nadzira Doolaanea, Abd Almonem Ab. Hadi, Hazrina
author_sort	Hanif, Nadzira
title	Formulation and characterization of cosmetic cream incorporating piper Betle Linn. extract
title_short	Formulation and characterization of cosmetic cream incorporating piper Betle Linn. extract
title_full	Formulation and characterization of cosmetic cream incorporating piper Betle Linn. extract
title_fullStr	Formulation and characterization of cosmetic cream incorporating piper Betle Linn. extract
title_full_unstemmed	Formulation and characterization of cosmetic cream incorporating piper Betle Linn. extract
title_sort	formulation and characterization of cosmetic cream incorporating piper betle linn. extract
publishDate	2017
url	http://irep.iium.edu.my/61757/ http://irep.iium.edu.my/61757/17/61757_Formulation%20and%20Characterization%20of%20Cosmetic%20Cream_complete.pdf
first_indexed	2023-09-18T21:27:35Z
last_indexed	2023-09-18T21:27:35Z
_version_	1777412294640140288

Formulation and characterization of cosmetic cream incorporating piper Betle Linn. extract

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