Selected natural agents used for cholesterol controls

Purpose – Various studies suggest that some of natural agents create a specific action of hypocholesterolemic effect. Considering this fact, the aim of this paper is to work on describing selected natural agents that may reduce cholesterol concentrations by different mechanism of actions. Design/me...

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Main Authors:	Abdul Latif, Nurul Hazwani, Bakhtiar, M. Taher, Md Jaffri, Juliana, Amri, Mohamad Shahreen, Abdul Kudos, Muhammad Badri, Wan Sulaiman, Wan Mohd Azizi, Darnis, Deny Susanti
Format:	Article
Language:	English English English
Published:	Emerald 2018
Subjects:	RS Pharmacy and materia medica RS192 Materia Medica-Pharmaceutical Technology
Online Access:	http://irep.iium.edu.my/62827/ http://irep.iium.edu.my/62827/ http://irep.iium.edu.my/62827/ http://irep.iium.edu.my/62827/7/62827%20Selected%20natural%20agents%20used%20for%20cholesterol%20controls%20SCOPUS.pdf http://irep.iium.edu.my/62827/13/62827_Selected%20natural%20agents%20used%20for%20cholesterol%20controls.pdf http://irep.iium.edu.my/62827/14/62827_Selected%20natural%20agents%20used%20for%20cholesterol%20controls_WOS.pdf

id	iium-62827
recordtype	eprints
spelling	iium-628272018-04-26T08:06:25Z http://irep.iium.edu.my/62827/ Selected natural agents used for cholesterol controls Abdul Latif, Nurul Hazwani Bakhtiar, M. Taher Md Jaffri, Juliana Amri, Mohamad Shahreen Abdul Kudos, Muhammad Badri Wan Sulaiman, Wan Mohd Azizi Darnis, Deny Susanti RS Pharmacy and materia medica RS192 Materia Medica-Pharmaceutical Technology Purpose – Various studies suggest that some of natural agents create a specific action of hypocholesterolemic effect. Considering this fact, the aim of this paper is to work on describing selected natural agents that may reduce cholesterol concentrations by different mechanism of actions. Design/methodology/approach – The advantages, phytochemical components and the mechanisms of the agents were reviewed and supported from the findings of the in vitro, double-blind and clinical studies from published journals, books and articles. The journals used in this review were published between 1987 and 2016, and are available from PubMed, ScienceDirect and Google Scholar. Findings – Plant stanols and sterols, turmeric, fenugreek, avocado, tomato, artichoke, red yeast rice and garlic showed a positive effect in maintaining cholesterol levels by specific mechanisms or actions. These agents each had a specific action in creating a hypocholesterolemic effect either by inhibition of the enzyme significant to the synthesis process, disturbing the absorption of cholesterol, conversion of cholesterol to other related forms and through the reduction of the oxidative stress. Research limitations/implications – However, this field still needs more studies as, currently, there is not any detailed information regarding the main active ingredients responsible for the mechanism to reduce cholesterol levels in humans. Originality/value – This paper enlightens the authors’ understanding of some natural agents that have the potential to be used in controlling cholesterol. Emerald 2018 Article PeerReviewed application/pdf en http://irep.iium.edu.my/62827/7/62827%20Selected%20natural%20agents%20used%20for%20cholesterol%20controls%20SCOPUS.pdf application/pdf en http://irep.iium.edu.my/62827/13/62827_Selected%20natural%20agents%20used%20for%20cholesterol%20controls.pdf application/pdf en http://irep.iium.edu.my/62827/14/62827_Selected%20natural%20agents%20used%20for%20cholesterol%20controls_WOS.pdf Abdul Latif, Nurul Hazwani and Bakhtiar, M. Taher and Md Jaffri, Juliana and Amri, Mohamad Shahreen and Abdul Kudos, Muhammad Badri and Wan Sulaiman, Wan Mohd Azizi and Darnis, Deny Susanti (2018) Selected natural agents used for cholesterol controls. Nutrition & Food Science, 48 (2). pp. 301-317. ISSN 0034-6659 https://www.emeraldinsight.com/doi/abs/10.1108/NFS-06-2017-0128 10.1108/NFS-06-2017-0128
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English English
topic	RS Pharmacy and materia medica RS192 Materia Medica-Pharmaceutical Technology
spellingShingle	RS Pharmacy and materia medica RS192 Materia Medica-Pharmaceutical Technology Abdul Latif, Nurul Hazwani Bakhtiar, M. Taher Md Jaffri, Juliana Amri, Mohamad Shahreen Abdul Kudos, Muhammad Badri Wan Sulaiman, Wan Mohd Azizi Darnis, Deny Susanti Selected natural agents used for cholesterol controls
description	Purpose – Various studies suggest that some of natural agents create a specific action of hypocholesterolemic effect. Considering this fact, the aim of this paper is to work on describing selected natural agents that may reduce cholesterol concentrations by different mechanism of actions. Design/methodology/approach – The advantages, phytochemical components and the mechanisms of the agents were reviewed and supported from the findings of the in vitro, double-blind and clinical studies from published journals, books and articles. The journals used in this review were published between 1987 and 2016, and are available from PubMed, ScienceDirect and Google Scholar. Findings – Plant stanols and sterols, turmeric, fenugreek, avocado, tomato, artichoke, red yeast rice and garlic showed a positive effect in maintaining cholesterol levels by specific mechanisms or actions. These agents each had a specific action in creating a hypocholesterolemic effect either by inhibition of the enzyme significant to the synthesis process, disturbing the absorption of cholesterol, conversion of cholesterol to other related forms and through the reduction of the oxidative stress. Research limitations/implications – However, this field still needs more studies as, currently, there is not any detailed information regarding the main active ingredients responsible for the mechanism to reduce cholesterol levels in humans. Originality/value – This paper enlightens the authors’ understanding of some natural agents that have the potential to be used in controlling cholesterol.
format	Article
author	Abdul Latif, Nurul Hazwani Bakhtiar, M. Taher Md Jaffri, Juliana Amri, Mohamad Shahreen Abdul Kudos, Muhammad Badri Wan Sulaiman, Wan Mohd Azizi Darnis, Deny Susanti
author_facet	Abdul Latif, Nurul Hazwani Bakhtiar, M. Taher Md Jaffri, Juliana Amri, Mohamad Shahreen Abdul Kudos, Muhammad Badri Wan Sulaiman, Wan Mohd Azizi Darnis, Deny Susanti
author_sort	Abdul Latif, Nurul Hazwani
title	Selected natural agents used for cholesterol controls
title_short	Selected natural agents used for cholesterol controls
title_full	Selected natural agents used for cholesterol controls
title_fullStr	Selected natural agents used for cholesterol controls
title_full_unstemmed	Selected natural agents used for cholesterol controls
title_sort	selected natural agents used for cholesterol controls
publisher	Emerald
publishDate	2018
url	http://irep.iium.edu.my/62827/ http://irep.iium.edu.my/62827/ http://irep.iium.edu.my/62827/ http://irep.iium.edu.my/62827/7/62827%20Selected%20natural%20agents%20used%20for%20cholesterol%20controls%20SCOPUS.pdf http://irep.iium.edu.my/62827/13/62827_Selected%20natural%20agents%20used%20for%20cholesterol%20controls.pdf http://irep.iium.edu.my/62827/14/62827_Selected%20natural%20agents%20used%20for%20cholesterol%20controls_WOS.pdf
first_indexed	2023-09-18T21:29:01Z
last_indexed	2023-09-18T21:29:01Z
_version_	1777412385489813504

Selected natural agents used for cholesterol controls

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