Prehypertensive state, mild hypertension, metabolic syndrome and cardiovascular risk factors among young adults in rural Malaysia

Introduction: Prehypertension precedes overt hypertension and has been acknowledged by many guidelines. Hypertension is an important risk factor for cardiovascular disease in Malaysia. Hypertension prevalence is at 42.6% and population-based control is poor at 26.8%. The objective of t...

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Main Authors:	Abdullah, Aszrin, Mohd. Shah, Azarisman Shah, Ab Rahman, Jamalludin, Abdul Razak, Tariq, Mohd Noor, Noriah
Format:	Article
Language:	English English English
Published:	International Islamic University Malaysia 2018
Subjects:	RC Internal medicine RC620 Specialties of Internal Medicine-Nutritional Diseases
Online Access:	http://irep.iium.edu.my/63475/ http://irep.iium.edu.my/63475/ http://irep.iium.edu.my/63475/1/Vol17-No1-p047054.pdf http://irep.iium.edu.my/63475/7/63475_Prehypertensive%20state%2C%20mild%20hypertension%2C%20metabolic%20syndrome%20_scopus.pdf http://irep.iium.edu.my/63475/13/63475_Prehypertensive%20state%2C%20mild%20hypertension%2C%20metabolic%20syndrome%20and%20cardiovascular%20risk%20factors%20among%20young%20adults%20in%20rural%20Malaysia_WOS.pdf

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spelling	iium-634752019-03-04T03:56:21Z http://irep.iium.edu.my/63475/ Prehypertensive state, mild hypertension, metabolic syndrome and cardiovascular risk factors among young adults in rural Malaysia Abdullah, Aszrin Mohd. Shah, Azarisman Shah Ab Rahman, Jamalludin Abdul Razak, Tariq Mohd Noor, Noriah RC Internal medicine RC620 Specialties of Internal Medicine-Nutritional Diseases Introduction: Prehypertension precedes overt hypertension and has been acknowledged by many guidelines. Hypertension is an important risk factor for cardiovascular disease in Malaysia. Hypertension prevalence is at 42.6% and population-based control is poor at 26.8%. The objective of the study is to ascertain the cardiovascular risk profile of prehypertensive and mildly hypertensive young adults against age-matched controls in rural Malaysia. Methods: 484(four hundred and eighty four) subjects attending primary care clinic were screened. 91 (Ninety one) young adults with pre/mild hypertension and normotensive, age-matched controls were enrolled. The blood pressure and biochemical profiles for both groups were assessed and compared. Results: Fifty-four subjects and 37 controls were enrolled. Amongst subjects, 46.3% had prehypertension and 53.7% had mild hypertension. Mean values compared to age- matched controls for MAP were 102.68 ± 7.48 vs 83.25 ± 6.08 mmHg (p< 0.001), LDL 3.75 ± 0.95 vs 3.32 ± 0.93 mmol/L (p=0.03), FBG 4.65 ± 0.54 vs 4.33 ± 0.42 mmol/L (p=0.03), BMI 28.81 ± 5.16 vs 24.12 ± 4.91 (p< 0.001). The mean BP was significantly associated with BMI, FBG, triglycerides, HDL and the TC/HDL ratio. Conclusions: Greater BMI, FBG, HDL, triglyceride levels and TC/HDL ratio characterised the young adults with pre/mild hypertension. The data suggests that hypertension in young adults is secondary to metabolic syndrome. International Islamic University Malaysia 2018-04 Article PeerReviewed application/pdf en http://irep.iium.edu.my/63475/1/Vol17-No1-p047054.pdf application/pdf en http://irep.iium.edu.my/63475/7/63475_Prehypertensive%20state%2C%20mild%20hypertension%2C%20metabolic%20syndrome%20_scopus.pdf application/pdf en http://irep.iium.edu.my/63475/13/63475_Prehypertensive%20state%2C%20mild%20hypertension%2C%20metabolic%20syndrome%20and%20cardiovascular%20risk%20factors%20among%20young%20adults%20in%20rural%20Malaysia_WOS.pdf Abdullah, Aszrin and Mohd. Shah, Azarisman Shah and Ab Rahman, Jamalludin and Abdul Razak, Tariq and Mohd Noor, Noriah (2018) Prehypertensive state, mild hypertension, metabolic syndrome and cardiovascular risk factors among young adults in rural Malaysia. International Medical Journal Malaysia, 17 (1). pp. 47-54. ISSN 1823-4631 http://iiumedic.net/imjm/v1/download/volume_17_no_1/Vol17-No1-p047054.pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English English
topic	RC Internal medicine RC620 Specialties of Internal Medicine-Nutritional Diseases
spellingShingle	RC Internal medicine RC620 Specialties of Internal Medicine-Nutritional Diseases Abdullah, Aszrin Mohd. Shah, Azarisman Shah Ab Rahman, Jamalludin Abdul Razak, Tariq Mohd Noor, Noriah Prehypertensive state, mild hypertension, metabolic syndrome and cardiovascular risk factors among young adults in rural Malaysia
description	Introduction: Prehypertension precedes overt hypertension and has been acknowledged by many guidelines. Hypertension is an important risk factor for cardiovascular disease in Malaysia. Hypertension prevalence is at 42.6% and population-based control is poor at 26.8%. The objective of the study is to ascertain the cardiovascular risk profile of prehypertensive and mildly hypertensive young adults against age-matched controls in rural Malaysia. Methods: 484(four hundred and eighty four) subjects attending primary care clinic were screened. 91 (Ninety one) young adults with pre/mild hypertension and normotensive, age-matched controls were enrolled. The blood pressure and biochemical profiles for both groups were assessed and compared. Results: Fifty-four subjects and 37 controls were enrolled. Amongst subjects, 46.3% had prehypertension and 53.7% had mild hypertension. Mean values compared to age- matched controls for MAP were 102.68 ± 7.48 vs 83.25 ± 6.08 mmHg (p< 0.001), LDL 3.75 ± 0.95 vs 3.32 ± 0.93 mmol/L (p=0.03), FBG 4.65 ± 0.54 vs 4.33 ± 0.42 mmol/L (p=0.03), BMI 28.81 ± 5.16 vs 24.12 ± 4.91 (p< 0.001). The mean BP was significantly associated with BMI, FBG, triglycerides, HDL and the TC/HDL ratio. Conclusions: Greater BMI, FBG, HDL, triglyceride levels and TC/HDL ratio characterised the young adults with pre/mild hypertension. The data suggests that hypertension in young adults is secondary to metabolic syndrome.
format	Article
author	Abdullah, Aszrin Mohd. Shah, Azarisman Shah Ab Rahman, Jamalludin Abdul Razak, Tariq Mohd Noor, Noriah
author_facet	Abdullah, Aszrin Mohd. Shah, Azarisman Shah Ab Rahman, Jamalludin Abdul Razak, Tariq Mohd Noor, Noriah
author_sort	Abdullah, Aszrin
title	Prehypertensive state, mild hypertension, metabolic syndrome and cardiovascular risk factors among young adults in rural Malaysia
title_short	Prehypertensive state, mild hypertension, metabolic syndrome and cardiovascular risk factors among young adults in rural Malaysia
title_full	Prehypertensive state, mild hypertension, metabolic syndrome and cardiovascular risk factors among young adults in rural Malaysia
title_fullStr	Prehypertensive state, mild hypertension, metabolic syndrome and cardiovascular risk factors among young adults in rural Malaysia
title_full_unstemmed	Prehypertensive state, mild hypertension, metabolic syndrome and cardiovascular risk factors among young adults in rural Malaysia
title_sort	prehypertensive state, mild hypertension, metabolic syndrome and cardiovascular risk factors among young adults in rural malaysia
publisher	International Islamic University Malaysia
publishDate	2018
url	http://irep.iium.edu.my/63475/ http://irep.iium.edu.my/63475/ http://irep.iium.edu.my/63475/1/Vol17-No1-p047054.pdf http://irep.iium.edu.my/63475/7/63475_Prehypertensive%20state%2C%20mild%20hypertension%2C%20metabolic%20syndrome%20_scopus.pdf http://irep.iium.edu.my/63475/13/63475_Prehypertensive%20state%2C%20mild%20hypertension%2C%20metabolic%20syndrome%20and%20cardiovascular%20risk%20factors%20among%20young%20adults%20in%20rural%20Malaysia_WOS.pdf
first_indexed	2023-09-18T21:30:02Z
last_indexed	2023-09-18T21:30:02Z
_version_	1777412448907689984

Prehypertensive state, mild hypertension, metabolic syndrome and cardiovascular risk factors among young adults in rural Malaysia

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