The comparative antimicrobial effect of Activated Virgin Coconut Oil (AVCO) and Virgin Coconut Oil (VCO) against dental caries-related pathogens

The present-day diet is astoundingly cariogenic, owing to the fact that high food intake with plenty of fermentable carbohydrates present in them. Classic regime against dental caries such as fluoride is often not able to cope with the resultant massive cariogenic challenge. Therefore, demands of al...

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Main Authors:	Haron, Ummi Aqilah, Abllah, Zurainie, Mohamad Nasir, Nur Ainatul Mardia
Format:	Conference or Workshop Item
Language:	English
Published:	2018
Subjects:	QR Microbiology
Online Access:	http://irep.iium.edu.my/65513/ http://irep.iium.edu.my/65513/ http://irep.iium.edu.my/65513/ http://irep.iium.edu.my/65513/1/65513_The%20Comparative%20Antimicrobial.pdf

id	iium-65513
recordtype	eprints
spelling	iium-655132018-09-07T03:44:30Z http://irep.iium.edu.my/65513/ The comparative antimicrobial effect of Activated Virgin Coconut Oil (AVCO) and Virgin Coconut Oil (VCO) against dental caries-related pathogens Haron, Ummi Aqilah Abllah, Zurainie Mohamad Nasir, Nur Ainatul Mardia QR Microbiology The present-day diet is astoundingly cariogenic, owing to the fact that high food intake with plenty of fermentable carbohydrates present in them. Classic regime against dental caries such as fluoride is often not able to cope with the resultant massive cariogenic challenge. Therefore, demands of alternatives for the classic regime in arresting issues related to oral health are always on the increase. In contemplation to improve and further develop novel antimicrobial compound, a great deal of research has gone into optimizing a lot of components presently available in natural sources which may help to contribute to the antimicrobial activity. The virgin coconut oil (VCO) is a case in point and has been the focus for decades as it has proven to possess antimicrobial features on Gram positive bacteria. Recently, there is a patterned Activated Virgin Coconut Oil (AVCO) that reported to have a broad antimicrobial spectrum. However, information regarding the inhibitory of AVCO and VCO against dental caries-related pathogens are yet to be established. In this study, we compared the antimicrobial effect of AVCO obtained from KL trading, Selangor, Malaysia, and VCO extracted in our laboratory. Their MIC and MBC against the selected dental caries-related pathogen; Streptococcus mutans, Lactobacillus casei and Candida albicans were determined. Out of the three tested organisms, L. casei was subjected to have a higher sensitivity towards AVCO (MIC: 0.78 mg/ml and MBC: 1.56mg/ml), followed by C. albicans (MIC: 3.12 mg/ml and MBC: 6.24 mg/ml) and S. mutans (MIC: 6.24 mg/ml and MBC: 24.96 mg/ml). In contrast to a positive finding of AVCO, VCO has shown no inhibitory effect on all tested dental caries-related pathogens. Furthermore, the time killing assay revealed that AVCO showed relatively quick-killing activity at the 8 hours of time for all tested organism. These finding correlates with that of AVCO possess bactericidal activity, thereby allowing the possible classification of the AVCO as being a bactericidal agent. 2018-02 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/65513/1/65513_The%20Comparative%20Antimicrobial.pdf Haron, Ummi Aqilah and Abllah, Zurainie and Mohamad Nasir, Nur Ainatul Mardia (2018) The comparative antimicrobial effect of Activated Virgin Coconut Oil (AVCO) and Virgin Coconut Oil (VCO) against dental caries-related pathogens. In: International Dental Conference of Sumatera Utara 2017 (IDCSU 2017), 7th-9th Dec. 2017, Sumatera Utara, Indonesia. https://www.atlantis-press.com/proceedings/idcsu-17/25891975 10.2991/idcsu-17.2018.51
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	QR Microbiology
spellingShingle	QR Microbiology Haron, Ummi Aqilah Abllah, Zurainie Mohamad Nasir, Nur Ainatul Mardia The comparative antimicrobial effect of Activated Virgin Coconut Oil (AVCO) and Virgin Coconut Oil (VCO) against dental caries-related pathogens
description	The present-day diet is astoundingly cariogenic, owing to the fact that high food intake with plenty of fermentable carbohydrates present in them. Classic regime against dental caries such as fluoride is often not able to cope with the resultant massive cariogenic challenge. Therefore, demands of alternatives for the classic regime in arresting issues related to oral health are always on the increase. In contemplation to improve and further develop novel antimicrobial compound, a great deal of research has gone into optimizing a lot of components presently available in natural sources which may help to contribute to the antimicrobial activity. The virgin coconut oil (VCO) is a case in point and has been the focus for decades as it has proven to possess antimicrobial features on Gram positive bacteria. Recently, there is a patterned Activated Virgin Coconut Oil (AVCO) that reported to have a broad antimicrobial spectrum. However, information regarding the inhibitory of AVCO and VCO against dental caries-related pathogens are yet to be established. In this study, we compared the antimicrobial effect of AVCO obtained from KL trading, Selangor, Malaysia, and VCO extracted in our laboratory. Their MIC and MBC against the selected dental caries-related pathogen; Streptococcus mutans, Lactobacillus casei and Candida albicans were determined. Out of the three tested organisms, L. casei was subjected to have a higher sensitivity towards AVCO (MIC: 0.78 mg/ml and MBC: 1.56mg/ml), followed by C. albicans (MIC: 3.12 mg/ml and MBC: 6.24 mg/ml) and S. mutans (MIC: 6.24 mg/ml and MBC: 24.96 mg/ml). In contrast to a positive finding of AVCO, VCO has shown no inhibitory effect on all tested dental caries-related pathogens. Furthermore, the time killing assay revealed that AVCO showed relatively quick-killing activity at the 8 hours of time for all tested organism. These finding correlates with that of AVCO possess bactericidal activity, thereby allowing the possible classification of the AVCO as being a bactericidal agent.
format	Conference or Workshop Item
author	Haron, Ummi Aqilah Abllah, Zurainie Mohamad Nasir, Nur Ainatul Mardia
author_facet	Haron, Ummi Aqilah Abllah, Zurainie Mohamad Nasir, Nur Ainatul Mardia
author_sort	Haron, Ummi Aqilah
title	The comparative antimicrobial effect of Activated Virgin Coconut Oil (AVCO) and Virgin Coconut Oil (VCO) against dental caries-related pathogens
title_short	The comparative antimicrobial effect of Activated Virgin Coconut Oil (AVCO) and Virgin Coconut Oil (VCO) against dental caries-related pathogens
title_full	The comparative antimicrobial effect of Activated Virgin Coconut Oil (AVCO) and Virgin Coconut Oil (VCO) against dental caries-related pathogens
title_fullStr	The comparative antimicrobial effect of Activated Virgin Coconut Oil (AVCO) and Virgin Coconut Oil (VCO) against dental caries-related pathogens
title_full_unstemmed	The comparative antimicrobial effect of Activated Virgin Coconut Oil (AVCO) and Virgin Coconut Oil (VCO) against dental caries-related pathogens
title_sort	comparative antimicrobial effect of activated virgin coconut oil (avco) and virgin coconut oil (vco) against dental caries-related pathogens
publishDate	2018
url	http://irep.iium.edu.my/65513/ http://irep.iium.edu.my/65513/ http://irep.iium.edu.my/65513/ http://irep.iium.edu.my/65513/1/65513_The%20Comparative%20Antimicrobial.pdf
first_indexed	2023-09-18T21:32:57Z
last_indexed	2023-09-18T21:32:57Z
_version_	1777412632647565312

The comparative antimicrobial effect of Activated Virgin Coconut Oil (AVCO) and Virgin Coconut Oil (VCO) against dental caries-related pathogens

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