Linum usitatissimum antibacterial activity on Pseudomona Aerigenosa in-vitro study

Flaxseed comes from the flax plant (Linum usitatissimum), which has been cultivated for domestic use since prehistoric times. Pseudomonas aeruginosa is a Gram-negative bacterium has the ability to survive in adverse environments and develop multiple antibiotic resistance mechanisms. This study aims...

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Main Authors:	Mohamed Yusoff, Nurul Fatihah, Mustafa Al-Ahmad, Basma Ezzat, Subramaniam, Pram Kumar, Mustafa, Nazih Shaban, Kashmola, Muhanad Ali Hamdon, Mokhtar@Makhtar, Khairani Idah, Darnis, Deny Susanti
Format:	Conference or Workshop Item
Language:	English
Published:	2018
Subjects:	RK Dentistry
Online Access:	http://irep.iium.edu.my/65765/ http://irep.iium.edu.my/65765/11/65765_abstract.pdf

id	iium-65765
recordtype	eprints
spelling	iium-657652018-09-05T03:53:50Z http://irep.iium.edu.my/65765/ Linum usitatissimum antibacterial activity on Pseudomona Aerigenosa in-vitro study Mohamed Yusoff, Nurul Fatihah Mustafa Al-Ahmad, Basma Ezzat Subramaniam, Pram Kumar Mustafa, Nazih Shaban Kashmola, Muhanad Ali Hamdon Mokhtar@Makhtar, Khairani Idah Darnis, Deny Susanti RK Dentistry Flaxseed comes from the flax plant (Linum usitatissimum), which has been cultivated for domestic use since prehistoric times. Pseudomonas aeruginosa is a Gram-negative bacterium has the ability to survive in adverse environments and develop multiple antibiotic resistance mechanisms. This study aims to evaluate the susceptibility of Pseudomonas aeruginosa (P. aeruginosa) in vitro to the ethanolic extract obtained from flax seed. This is a laboratory experimental in vitro study using P. aeruginosa cultured in nutrient agar. The pathogen then was inoculated in nutrient based broth and incubated for 24hours. Flaxseed extract efficacy was tested by measurement of the zone of inhibition. The result of the extracts antimicrobial activities were compared with streptomycin as positive control and DMSO as negative control. The statistical analysis was done by using SPSS19.There is positive antibacterial effects of flaxseed extract against Pseudomona Aerigenosa and it was comparable in efficacy to that of Streptomycin. This study concludes that flaxseed extract can help in inhibiting Pseudomona Aerigenosa activity. The implication of this result will be useful in propagating the use of natural based product as therapeutic drug against the chemical synthetic products. The results of the present study scientifically validate the inhibitory capacity of Linum usitatissimum as antibiotic against one of the most resistant pathogens and contribute towards the development of new treatment options based on natural products. 2018-08-14 Conference or Workshop Item PeerReviewed application/pdf en http://irep.iium.edu.my/65765/11/65765_abstract.pdf Mohamed Yusoff, Nurul Fatihah and Mustafa Al-Ahmad, Basma Ezzat and Subramaniam, Pram Kumar and Mustafa, Nazih Shaban and Kashmola, Muhanad Ali Hamdon and Mokhtar@Makhtar, Khairani Idah and Darnis, Deny Susanti (2018) Linum usitatissimum antibacterial activity on Pseudomona Aerigenosa in-vitro study. In: The International Conference on Oral Immunology & Oral Microbiology (ICOIOM) 2018, 15 August 2018, Faculty of Dentistry, University of Malaya. (Unpublished)
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English
topic	RK Dentistry
spellingShingle	RK Dentistry Mohamed Yusoff, Nurul Fatihah Mustafa Al-Ahmad, Basma Ezzat Subramaniam, Pram Kumar Mustafa, Nazih Shaban Kashmola, Muhanad Ali Hamdon Mokhtar@Makhtar, Khairani Idah Darnis, Deny Susanti Linum usitatissimum antibacterial activity on Pseudomona Aerigenosa in-vitro study
description	Flaxseed comes from the flax plant (Linum usitatissimum), which has been cultivated for domestic use since prehistoric times. Pseudomonas aeruginosa is a Gram-negative bacterium has the ability to survive in adverse environments and develop multiple antibiotic resistance mechanisms. This study aims to evaluate the susceptibility of Pseudomonas aeruginosa (P. aeruginosa) in vitro to the ethanolic extract obtained from flax seed. This is a laboratory experimental in vitro study using P. aeruginosa cultured in nutrient agar. The pathogen then was inoculated in nutrient based broth and incubated for 24hours. Flaxseed extract efficacy was tested by measurement of the zone of inhibition. The result of the extracts antimicrobial activities were compared with streptomycin as positive control and DMSO as negative control. The statistical analysis was done by using SPSS19.There is positive antibacterial effects of flaxseed extract against Pseudomona Aerigenosa and it was comparable in efficacy to that of Streptomycin. This study concludes that flaxseed extract can help in inhibiting Pseudomona Aerigenosa activity. The implication of this result will be useful in propagating the use of natural based product as therapeutic drug against the chemical synthetic products. The results of the present study scientifically validate the inhibitory capacity of Linum usitatissimum as antibiotic against one of the most resistant pathogens and contribute towards the development of new treatment options based on natural products.
format	Conference or Workshop Item
author	Mohamed Yusoff, Nurul Fatihah Mustafa Al-Ahmad, Basma Ezzat Subramaniam, Pram Kumar Mustafa, Nazih Shaban Kashmola, Muhanad Ali Hamdon Mokhtar@Makhtar, Khairani Idah Darnis, Deny Susanti
author_facet	Mohamed Yusoff, Nurul Fatihah Mustafa Al-Ahmad, Basma Ezzat Subramaniam, Pram Kumar Mustafa, Nazih Shaban Kashmola, Muhanad Ali Hamdon Mokhtar@Makhtar, Khairani Idah Darnis, Deny Susanti
author_sort	Mohamed Yusoff, Nurul Fatihah
title	Linum usitatissimum antibacterial activity on Pseudomona Aerigenosa in-vitro study
title_short	Linum usitatissimum antibacterial activity on Pseudomona Aerigenosa in-vitro study
title_full	Linum usitatissimum antibacterial activity on Pseudomona Aerigenosa in-vitro study
title_fullStr	Linum usitatissimum antibacterial activity on Pseudomona Aerigenosa in-vitro study
title_full_unstemmed	Linum usitatissimum antibacterial activity on Pseudomona Aerigenosa in-vitro study
title_sort	linum usitatissimum antibacterial activity on pseudomona aerigenosa in-vitro study
publishDate	2018
url	http://irep.iium.edu.my/65765/ http://irep.iium.edu.my/65765/11/65765_abstract.pdf
first_indexed	2023-09-18T21:33:17Z
last_indexed	2023-09-18T21:33:17Z
_version_	1777412654012301312

Linum usitatissimum antibacterial activity on Pseudomona Aerigenosa in-vitro study

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