Functional foods from Quercus infectoria galls and their bioactivities

Plant has antimicrobial properties as the extract is used in food industry, pharmaceuticals and alternative medicine. The aims of this study were to isolate metabolites from Quercus infectoria galls and to determine the antimicrobial and antioxidant properties of extracts and isolated compounds. The...

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Main Authors:	Sulaiman, Fatimatul Akmal, Mohamed Iqbal, Mohammad Anwar, Darnis, Deny Susanti, Adam, Farook, Bakhtiar, M. Taher
Format:	Conference or Workshop Item
Language:	English English
Published:	2018
Subjects:	QD Chemistry
Online Access:	http://irep.iium.edu.my/65955/ http://irep.iium.edu.my/65955/ http://irep.iium.edu.my/65955/21/65955%20Functional%20Foods%20from%20Quercus%20infectoria%20Galls%20and%20Their%20Bioactivities.pdf http://irep.iium.edu.my/65955/20/65955%20Poster.pdf

id	iium-65955
recordtype	eprints
spelling	iium-659552018-09-26T03:43:25Z http://irep.iium.edu.my/65955/ Functional foods from Quercus infectoria galls and their bioactivities Sulaiman, Fatimatul Akmal Mohamed Iqbal, Mohammad Anwar Darnis, Deny Susanti Adam, Farook Bakhtiar, M. Taher QD Chemistry Plant has antimicrobial properties as the extract is used in food industry, pharmaceuticals and alternative medicine. The aims of this study were to isolate metabolites from Quercus infectoria galls and to determine the antimicrobial and antioxidant properties of extracts and isolated compounds. The galls were extracted using soxhlet apparatus with n-hexane (HEX), dichloromethane (DCM) and methanol (MeOH), successively. The crude extracts were fractionated and separated using chromatographic techniques on silica gel. The isolated compounds were characterized using spectroscopic techniques. The antimicrobial activities were determined using disc diffusion method. The antioxidant activities were determined DPPH free radical scavenging activity and β-carotene bleaching assay. The cytotoxicity of isolated compounds was tested on MCF-7 using MTT assay. Methyl gallate (QIM 1) and gallic acid (QIM 2) were isolated from MeOH extract. The extracts and isolated compounds showed antimicrobial activities against Staphylococcus aureus, Bacillus cereus, Pseudomonas aeruginosa, Escherichia coli Candida albicans, Candida krusei and Aspergillus niger ATCC16404. In β-carotene bleaching assay, QIM 1 and QIM 2 exhibited 67 % and 66 % antioxidant activity. The present study revealed that isolated compounds showed potential as antioxidant agent and had cytotoxic effect on MCF-7. Meanwhile, the compound QIM 2 had antimicrobial properties and synergistic effect with chloramphenicol. 2018 Conference or Workshop Item NonPeerReviewed application/pdf en http://irep.iium.edu.my/65955/21/65955%20Functional%20Foods%20from%20Quercus%20infectoria%20Galls%20and%20Their%20Bioactivities.pdf application/pdf en http://irep.iium.edu.my/65955/20/65955%20Poster.pdf Sulaiman, Fatimatul Akmal and Mohamed Iqbal, Mohammad Anwar and Darnis, Deny Susanti and Adam, Farook and Bakhtiar, M. Taher (2018) Functional foods from Quercus infectoria galls and their bioactivities. In: 34th International Conference on Natural Products (ICNP 2018), 19th-21st March 2018, Pulau Pinang. (Unpublished) http://www.icnp2018.usm.my/images/ICNP/E-Abstract/ICNP-2018-E-Book.pdf
repository_type	Digital Repository
institution_category	Local University
institution	International Islamic University Malaysia
building	IIUM Repository
collection	Online Access
language	English English
topic	QD Chemistry
spellingShingle	QD Chemistry Sulaiman, Fatimatul Akmal Mohamed Iqbal, Mohammad Anwar Darnis, Deny Susanti Adam, Farook Bakhtiar, M. Taher Functional foods from Quercus infectoria galls and their bioactivities
description	Plant has antimicrobial properties as the extract is used in food industry, pharmaceuticals and alternative medicine. The aims of this study were to isolate metabolites from Quercus infectoria galls and to determine the antimicrobial and antioxidant properties of extracts and isolated compounds. The galls were extracted using soxhlet apparatus with n-hexane (HEX), dichloromethane (DCM) and methanol (MeOH), successively. The crude extracts were fractionated and separated using chromatographic techniques on silica gel. The isolated compounds were characterized using spectroscopic techniques. The antimicrobial activities were determined using disc diffusion method. The antioxidant activities were determined DPPH free radical scavenging activity and β-carotene bleaching assay. The cytotoxicity of isolated compounds was tested on MCF-7 using MTT assay. Methyl gallate (QIM 1) and gallic acid (QIM 2) were isolated from MeOH extract. The extracts and isolated compounds showed antimicrobial activities against Staphylococcus aureus, Bacillus cereus, Pseudomonas aeruginosa, Escherichia coli Candida albicans, Candida krusei and Aspergillus niger ATCC16404. In β-carotene bleaching assay, QIM 1 and QIM 2 exhibited 67 % and 66 % antioxidant activity. The present study revealed that isolated compounds showed potential as antioxidant agent and had cytotoxic effect on MCF-7. Meanwhile, the compound QIM 2 had antimicrobial properties and synergistic effect with chloramphenicol.
format	Conference or Workshop Item
author	Sulaiman, Fatimatul Akmal Mohamed Iqbal, Mohammad Anwar Darnis, Deny Susanti Adam, Farook Bakhtiar, M. Taher
author_facet	Sulaiman, Fatimatul Akmal Mohamed Iqbal, Mohammad Anwar Darnis, Deny Susanti Adam, Farook Bakhtiar, M. Taher
author_sort	Sulaiman, Fatimatul Akmal
title	Functional foods from Quercus infectoria galls and their bioactivities
title_short	Functional foods from Quercus infectoria galls and their bioactivities
title_full	Functional foods from Quercus infectoria galls and their bioactivities
title_fullStr	Functional foods from Quercus infectoria galls and their bioactivities
title_full_unstemmed	Functional foods from Quercus infectoria galls and their bioactivities
title_sort	functional foods from quercus infectoria galls and their bioactivities
publishDate	2018
url	http://irep.iium.edu.my/65955/ http://irep.iium.edu.my/65955/ http://irep.iium.edu.my/65955/21/65955%20Functional%20Foods%20from%20Quercus%20infectoria%20Galls%20and%20Their%20Bioactivities.pdf http://irep.iium.edu.my/65955/20/65955%20Poster.pdf
first_indexed	2023-09-18T21:33:35Z
last_indexed	2023-09-18T21:33:35Z
_version_	1777412672473530368

Functional foods from Quercus infectoria galls and their bioactivities

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