Metabolic profiling of flavonoids, saponins, alkaloids, and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS

Metabolic profiling of flavonoids, saponins, alkaloids, and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS

The leaves of Vernonia cinerea are widely used for medicinal purposes. Although, different studies have reported on the biological activities of the plant extracts whereas the tentative assignment of secondary metabolites that include flavonoids, saponins, alkaloids, and terpenoids had not been repo...

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Main Authors: Alara, Oluwaseun Ruth, Abdurahman, Nour Hamid, Ukaegbu, Chinonso Ishmael, Azhari, Nour Hamid, Kabbashi, Nassereldeen Ahmed
Format: Article
Language:English
English
Published: Taylors & Francis 2018
Subjects:
TP155 Chemical engineering
Online Access:http://irep.iium.edu.my/66702/
http://irep.iium.edu.my/66702/
http://irep.iium.edu.my/66702/
http://irep.iium.edu.my/66702/7/66702%20Metabolic%20profiling%20of%20flavonoids%2C%20saponins%2C%20alkaloids%2C%20and%20terpenoids.pdf
http://irep.iium.edu.my/66702/8/66702%20Metabolic%20profiling%20of%20flavonoids%2C%20saponins%2C%20alkaloids%2C%20and%20terpenoids%20%20SCOPUS.pdf
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spelling iium-667022018-10-18T03:03:27Z http://irep.iium.edu.my/66702/ Metabolic profiling of flavonoids, saponins, alkaloids, and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS Alara, Oluwaseun Ruth Abdurahman, Nour Hamid Ukaegbu, Chinonso Ishmael Azhari, Nour Hamid Kabbashi, Nassereldeen Ahmed TP155 Chemical engineering The leaves of Vernonia cinerea are widely used for medicinal purposes. Although, different studies have reported on the biological activities of the plant extracts whereas the tentative assignment of secondary metabolites that include flavonoids, saponins, alkaloids, and terpenoids had not been reported. Thus, this study tentatively assigned the flavonoids, saponins, alkaloids, and terpenoids in the extract of V. cinerea leaves that are mainly responsible for the reported activities. Liquid chromatography-mass spectrometry quadrupole time of flight (LC-Q-TOF-MS) analysis was employed in the assignments. The results obtained showed that a total number of 221 compounds were tentatively assigned in the extract of V. cinerea leaves which include 64 flavonoids, 13 saponins, 36 alkaloids, and 108 terpenoids. These phytochemicals can further be isolated, purified, characterized, and quantified due to their importance. Taylors & Francis 2018 Article PeerReviewed application/pdf en http://irep.iium.edu.my/66702/7/66702%20Metabolic%20profiling%20of%20flavonoids%2C%20saponins%2C%20alkaloids%2C%20and%20terpenoids.pdf application/pdf en http://irep.iium.edu.my/66702/8/66702%20Metabolic%20profiling%20of%20flavonoids%2C%20saponins%2C%20alkaloids%2C%20and%20terpenoids%20%20SCOPUS.pdf Alara, Oluwaseun Ruth and Abdurahman, Nour Hamid and Ukaegbu, Chinonso Ishmael and Azhari, Nour Hamid and Kabbashi, Nassereldeen Ahmed (2018) Metabolic profiling of flavonoids, saponins, alkaloids, and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS. Journal of Liquid Chromatography & Related Technologies. pp. 1-10. ISSN 1082-6076 E-ISSN 520-572X (In Press) https://www.tandfonline.com/doi/abs/10.1080/10826076.2018.1511995?journalCode=ljlc20 10.1080/10826076.2018.1511995
repository_type Digital Repository
institution_category Local University
institution International Islamic University Malaysia
building IIUM Repository
collection Online Access
language English
English
topic TP155 Chemical engineering
spellingShingle TP155 Chemical engineering
Alara, Oluwaseun Ruth
Abdurahman, Nour Hamid
Ukaegbu, Chinonso Ishmael
Azhari, Nour Hamid
Kabbashi, Nassereldeen Ahmed
Metabolic profiling of flavonoids, saponins, alkaloids, and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS
description The leaves of Vernonia cinerea are widely used for medicinal purposes. Although, different studies have reported on the biological activities of the plant extracts whereas the tentative assignment of secondary metabolites that include flavonoids, saponins, alkaloids, and terpenoids had not been reported. Thus, this study tentatively assigned the flavonoids, saponins, alkaloids, and terpenoids in the extract of V. cinerea leaves that are mainly responsible for the reported activities. Liquid chromatography-mass spectrometry quadrupole time of flight (LC-Q-TOF-MS) analysis was employed in the assignments. The results obtained showed that a total number of 221 compounds were tentatively assigned in the extract of V. cinerea leaves which include 64 flavonoids, 13 saponins, 36 alkaloids, and 108 terpenoids. These phytochemicals can further be isolated, purified, characterized, and quantified due to their importance.
format Article
author Alara, Oluwaseun Ruth
Abdurahman, Nour Hamid
Ukaegbu, Chinonso Ishmael
Azhari, Nour Hamid
Kabbashi, Nassereldeen Ahmed
author_facet Alara, Oluwaseun Ruth
Abdurahman, Nour Hamid
Ukaegbu, Chinonso Ishmael
Azhari, Nour Hamid
Kabbashi, Nassereldeen Ahmed
author_sort Alara, Oluwaseun Ruth
title Metabolic profiling of flavonoids, saponins, alkaloids, and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS
title_short Metabolic profiling of flavonoids, saponins, alkaloids, and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS
title_full Metabolic profiling of flavonoids, saponins, alkaloids, and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS
title_fullStr Metabolic profiling of flavonoids, saponins, alkaloids, and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS
title_full_unstemmed Metabolic profiling of flavonoids, saponins, alkaloids, and terpenoids in the extract from Vernonia cinerea leaf using LC-Q-TOF-MS
title_sort metabolic profiling of flavonoids, saponins, alkaloids, and terpenoids in the extract from vernonia cinerea leaf using lc-q-tof-ms
publisher Taylors & Francis
publishDate 2018
url http://irep.iium.edu.my/66702/
http://irep.iium.edu.my/66702/
http://irep.iium.edu.my/66702/
http://irep.iium.edu.my/66702/7/66702%20Metabolic%20profiling%20of%20flavonoids%2C%20saponins%2C%20alkaloids%2C%20and%20terpenoids.pdf
http://irep.iium.edu.my/66702/8/66702%20Metabolic%20profiling%20of%20flavonoids%2C%20saponins%2C%20alkaloids%2C%20and%20terpenoids%20%20SCOPUS.pdf
first_indexed 2023-09-18T21:34:43Z
last_indexed 2023-09-18T21:34:43Z
_version_ 1777412744025210880

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