Topical co-delivery of indomethacin and nigella sativa L. essential oil in poly-cappa-caprolactone nanoparticles: in vitro study of anti-inflammatory activity
Indomethacin is a potent, nonselective Non-steroidal Antiinflammatory Drug (NSAID) but its low water-solubility precludes its use as topical dosage form. As with other NSAIDs, the systemic delivery is associated with high risk of serious gastrointestinal adverse events including bleeding, ulcera...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
International Journal of Advanced Research (IJAR)
2018
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| Subjects: | |
| Online Access: | http://irep.iium.edu.my/66791/ http://irep.iium.edu.my/66791/ http://irep.iium.edu.my/66791/ http://irep.iium.edu.my/66791/1/443_IJAR%20indomethacin%20microparticles.pdf |